File Name : figure s1.tif Caption : figure s1. string ppi networks for proteins extracted by 60% tsm (left) and 5% pca (right). node size represents node degree (number of interaction partners), and the mean node degree is reported for each network (tsm: 12.42; pca: 4.83). File Name : figure s2.tif Caption : figure s2. proteome coverage and quantitative reproducibility of the neat plasma and orthogonal extraction workflows in three individual healthy donors. (a) total numbers of proteins identified by the neat plasma workflow using neat plasma and the orthogonal extraction workflow across the three donor samples; (b) distribution of protein-level coefficients of variation (cvs) for proteins quantified in the neat plasma workflow across three donors; (c) distribution of protein-level cvs for proteins quantified in the orthogonal extraction workflow across three donors.