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["Gene Symbol","Official full name","Function","Cellular component","Pathways","Virulance","Essentiality","Host Homolog","Interacting Host proteins","Host Pathways"]
[]
["groEL","60 kDa chaperonin"," MF: ATP binding, ATPase activity, identical protein binding, unfolded protein binding\n\nBP: cell cycle, cell division, phage assembly, protein refolding, response to heat","Cytosol/membrane","RNA degradation","yes","yes","yes","ZNF326, HSF1, IGHV4-31, NQO2, HAX1, HG2A, ARBK2, PSME2, LAG3"]
["carA","Carbamoyl phosphate synthetase small subunit","EC=6.3.5.5\nMF: ATP binding, carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity, protein binding \nBP: pyrimidine nucleotide biosynthetic process, glutamine catabolic process, carbamoyl phosphate biosynthetic process, arginine biosynthetic process, 'de novo' pyrimidine base biosynthetic process","Cytoplasmic","Pyrimidine metabolism, Alanine, aspartate and glutamate metabolism, Metabolic pathways, Dioxin degradation, Ascorbate and aldarate metabolism -","yes","yes","yes","N42L2, PLS3, S10A9, CPT1A, NCOA3"]
["carB","Carbamoyl phosphate synthase large subunit","EC=6.3.5.5\nMF:  ATP binding, carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity, magnesium ion binding, manganese ion binding.\nBP: arginine biosynthetic process, pyrimidine nucleotide biosynthetic process","Cytoplasmic/Inner membrane","Pyrimidine metabolism, Alanine, aspartate and glutamate metabolism, Metabolic pathways","yes","yes","yes","GDPD5, SMARCC1, CHD8, DAAM1, RHG29, SF3B1, IFIT2, BCAP31, TGFB1, PPGB,PTPRC, NFKB1"]
["leuD","3-isopropylmalate dehydratase small subunit ","EC=4.2.1.33\nMF: 3-isopropylmalate dehydratase activity\nBP: leucine biosynthetic process","Outer membrane","Valine, leucine and isoleucine biosynthesis, C5-Branched dibasic acid metabolism, Metabolic pathways, Biosynthesis of secondary metabolites","yes","yes","yes","HELZ, CPT1A, CTSD, METTL23, YWHAZ, ZNF26, NBPF16, C12orf35,  PSME1, NFKB1"]
["pgk","Phosphoglycerate kinase","EC=2.7.2.3\nMF: ATP binding, phosphoglycerate kinase activity\nBP: glycolysis\n","Cytoplasmic","Glycolysis / Gluconeogenesis, Metabolic pathways, Biosynthesis of secondary metabolites, Microbial metabolism in diverse environments","yes","yes","yes","TAF1, PSMB4, LOC100507419"]
["gluA","Glutamate ABC transport system ATP-binding protein","MF: ATP binding, ATPase activity\nBP: Amino-acid transport Transport","Cytoplasmic/inner membrane","ABC transporters","yes","yes","yes","RABEP1, HTRA2, IGHV4-31"]
["trpB","Tryptophan synthase beta subunit ","MF: tryptophan synthase activity, pyridoxal phosphate binding\nBP: Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis","Cytoplasmic/periplasmic","Glycine, serine and threonine metabolism, Phenylalanine, tyrosine and tryptophan biosynthesis, Metabolic pathways,Biosynthesis of secondary metabolites","yes","yes","yes","EFEMP1, B2M, CIZ1, PCYT1A, VWF"]
["ack","Acetate kinase ","EC=2.7.2.1\nMF: ATP binding, acetate kinase activity, zinc ion binding.\nBP: organic acid metabolic process","Cytosol/membrane","Taurine and hypotaurine metabolism, Pyruvate metabolism, Propanoate metabolism, Methane metabolism, Metabolic pathways, Microbial metabolism in diverse environments","yes","yes","No","PRDX3","Apoptosis, Prostaglandin 2 biosynthesis and metabolism, Mitochondrial Dysfunction, Oxidative Stress, and Antioxidant Defense"]
["ureG","Urease accessory protein UreG","MF: ATP binding, GTP binding, nickel cation binding.\nBP: Nickel insertion","Cytoplasmic ","NO","yes","yes","yes","DNMT1"]
["clpP","ATP-dependent Clp protease proteolytic subunit 2","MF: peptidase activity.\nBP: proteolysis","Cytoplasmic ","NO","yes","yes","yes","RABGAP1L, ELF2"]
["rpoC","DNA-directed RNA polymerase subunit beta","EC=2.7.7.6\nMF: DNA binding, DNA-directed RNA polymerase activity, protein binding.\nBP: Transcription","Extracellular, innermembrane","Purine metabolism, Pyrimidine metabolism,Metabolic pathways, RNA polymerase, Ribosome","yes","yes","yes","NCOR1, CSNK2B"]
["rpoB","DNA-directed RNA polymerase subunit beta","\nEC=2.7.7.6\nMF: Nucleotidyltransferase, Transferase,DNA binding, DNA-directed RNA polymerase activity, protein binding, ribonucleoside binding.\nBP: Transcription","Cytoplasmic,inner membrane, outer membrane","Purine metabolism, Pyrimidine metabolism, Metabolic pathways, RNA polymerase","yes","yes","yes","DPYD, MRFAP1, DHX32, CD74, SLK, SMCHD1, PCF11, USP28, DAG1, TTLL3, UFL1, MAT2A, KLRB1, ZNF24 , PPM1A , SLC2A3, ZZZ3, PIAS3, SFXN3, ZN720, TRIM22, PIK3R1, CLIC1, DDX46 , VAPA, HSP90B1, RNF212, KIAA0240, ZNF277, MRPL1, AMBRA1, USP54, MARK3, IGKC, HAX1, CTGF, C12orf35, TEF, CDKN2A, COL3A1, ZNF506, DENND4B, VPS18, USP9X, HSP90B1, FHL2 , SRSF3, CHRDL1, OGT, IQGAP1, TAPBP, IGHA2, MRC1, CCR1,  LRP4,  JUN,  NCK1,   SLCO1A2, NEB2, CHML, IGHV4-31, HAX1, CTGF, PSMD1, RNF212, SRSF3, AMBRA1, CSDE1, CCDC57, ZNF506, HLF, DENND4B, DDX46, EF1G, C14orf166, CTNB1, PSD3, MATR3, SLU7, DAZAP2, DLGAP4, VPS18 "]
["glgC","Glucose-1-phosphate adenylyltransferase","EC=2.7.7.27\nMF: glucose-1-phosphate adenylyltransferase activity, ATP binding.\nBP: glycogen biosynthetic process","Outer membrane","Starch and sucrose metabolism, Amino sugar and nucleotide sugar metabolism, Metabolic pathways","yes","yes","yes","NINJ1, IGHV4-31"]
["dnaA","Chromosomal replication initiator protein DnaA","MF:  ATP binding, DNA replication origin binding, nucleoside-triphosphatase activity\nBP: DNA-dependent DNA replication initiation, regulation of DNA replication\n","Extracellular, outer membrane, Periplasmic","Two-component system","yes","yes","yes","LAMA5, TINAGL1, IGHV4-31"]