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["Sup.Tab.S4B"]
["Gene ontonolgy analysis for all significant differentially expressed proteins between group 1 and group 2 cells"]
[]
["GOFFA FOR 196 UPREGULATED PROTEINS (p < 0.01, E ≥ 2.0)"]
["GO TERM (Biological process)","GO ID","P-VALUE","#PROTEINS","E-VALUE"]
["biosynthetic process","GO:0009058",3e-06,34,2.34]
["macromolecule biosynthetic process","GO:0009059",1e-06,25,3.05]
["cellular component assembly","GO:0022607",0,24,3.66]
["biological adhesion","GO:0022610",0.000932,21,2.13]
["cell adhesion","GO:0007155",0.000932,21,2.13]
["macromolecular complex assembly","GO:0065003",1e-06,21,3.46]
["translation","GO:0006412",1e-06,20,3.57]
["proteolysis","GO:0006508",0.000714,19,2.29]
["catabolic process","GO:0009056",0.000628,18,2.38]
["cellular catabolic process","GO:0044248",0.000102,17,2.88]
["cellular biosynthetic process","GO:0044249",0.002541,16,2.22]
["regulation of protein metabolic process","GO:0051246",1e-06,16,4.48]
["localization of cell","GO:0051674",3.2e-05,15,3.49]
["nitrogen compound metabolic process","GO:0006807",8.5e-05,15,3.2]
["cell motility","GO:0006928",3.2e-05,15,3.49]
["amine metabolic process","GO:0009308",3.2e-05,15,3.49]
["organic acid metabolic process","GO:0006082",0.001236,14,2.57]
["carboxylic acid metabolic process","GO:0019752",0.00121,14,2.58]
["carbohydrate metabolic process","GO:0005975",0.002439,13,2.49]
["amino acid and derivative metabolic process","GO:0006519",0.000296,12,3.34]
["macromolecule catabolic process","GO:0009057",0.008664,11,2.32]
["cellular carbohydrate metabolic process","GO:0044262",0.000792,11,3.18]
["ribonucleoprotein complex biogenesis and assembly","GO:0022613",2.3e-05,10,5.29]
["alcohol metabolic process","GO:0006066",0.001902,10,3.04]
["amino acid metabolic process","GO:0006520",0.000642,10,3.51]
["protein complex assembly","GO:0006461",0.003535,10,2.78]
["protein-RNA complex assembly","GO:0022618",5e-06,9,7.25]
["regulation of biosynthetic process","GO:0009889",0.001846,8,3.62]
["actin cytoskeleton organization and biogenesis","GO:0030036",0.0086,8,2.79]
["regulation of cellular biosynthetic process","GO:0031326",0.004437,7,3.46]
["monosaccharide metabolic process","GO:0005996",0.001719,7,4.11]
["regulation of translation","GO:0006417",0.002672,7,3.8]
["translational initiation","GO:0006413",1.3e-05,7,9.13]
["regulation of translational initiation","GO:0006446",1e-06,7,13.18]
["alcohol catabolic process","GO:0046164",0.000404,6,6.34]
["carbohydrate catabolic process","GO:0016052",0.001491,6,4.93]
["negative regulation of protein metabolic process","GO:0051248",0.000964,6,5.37]
["cellular carbohydrate catabolic process","GO:0044275",0.001217,6,5.13]
["hexose metabolic process","GO:0019318",0.006481,6,3.65]
["monosaccharide catabolic process","GO:0046365",0.000369,6,6.45]
["regulation of cellular component organization and biogenesis","GO:0051128",0.003919,5,4.85]
["wound healing","GO:0042060",0.008599,5,4.01]
["cell-matrix adhesion","GO:0007160",0.008599,5,4.01]
["negative regulation of cell organization and biogenesis","GO:0051129",0.00048,5,7.83]
["protein depolymerization","GO:0051261",0.000368,5,8.29]
["integrin-mediated signaling pathway","GO:0007229",0.003147,5,5.11]
["peptidyl-amino acid modification","GO:0018193",0.008488,5,4.03]
["glucose metabolic process","GO:0006006",0.006025,5,4.38]
["hexose catabolic process","GO:0019320",0.002269,5,5.52]
["glucose catabolic process","GO:0006007",0.001424,5,6.14]
["regulation of cell adhesion","GO:0030155",0.00436,4,6.11]
["glycolysis","GO:0006096",0.005477,4,5.72]
["cytoplasm organization and biogenesis","GO:0007028",0.0012,3,14.45]
["epithelial cell proliferation","GO:0050673",0.001904,3,12.32]
["learning and/or memory","GO:0007611",0.004558,3,9.05]
["regulation of epithelial cell proliferation","GO:0050678",0.001566,3,13.18]
["amino sugar metabolic process","GO:0006040",0.003559,3,9.88]
["nucleotide catabolic process","GO:0009166",0.001412,3,13.66]
["positive regulation of epithelial cell proliferation","GO:0050679",0.000839,3,16.33]
["glucosamine metabolic process","GO:0006041",0.001815,3,12.52]
["actin filament depolymerization","GO:0030042",0.004406,3,9.16]
["N-acetylglucosamine metabolic process","GO:0006044",0.001646,3,12.95]
["regulation of actin filament depolymerization","GO:0030834",0.004406,3,9.16]
["negative regulation of actin filament depolymerization","GO:0030835",0.004406,3,9.16]
["actomyosin structure organization and biogenesis","GO:0031032",0.001646,3,12.95]
["actin filament capping","GO:0051693",0.003692,3,9.76]
["barbed-end actin filament capping","GO:0051016",0.003692,3,9.76]
["localization within membrane","GO:0051668",0.008657,2,14.31]
["cell-substrate junction assembly","GO:0007044",0.00161,2,33.39]
["nucleotide-sugar metabolic process","GO:0009225",0.005215,2,18.55]
["protein insertion into membrane","GO:0051205",0.004481,2,20.03]
["DNA ligation","GO:0006266",0.002327,2,27.82]
["amino sugar biosynthetic process","GO:0046349",0.000157,2,100.16]
["endoderm development","GO:0007492",0.002595,2,26.36]
["biogenic amine catabolic process","GO:0042402",0.00964,2,13.54]
["positive regulation of cell migration","GO:0030335",0.004841,2,19.26]
["protein heterooligomerization","GO:0051291",0.006001,2,17.27]
["glucosamine biosynthetic process","GO:0006042",9.5e-05,2,125.2]
["UDP-N-acetylglucosamine metabolic process","GO:0006047",0.000561,2,55.65]
["N-acetylglucosamine biosynthetic process","GO:0006045",9.5e-05,2,125.2]
["UDP-N-acetylglucosamine biosynthetic process","GO:0006048",9.5e-05,2,125.2]
["nuclear mRNA 3'-splice site recognition","GO:0000389",0.001202,2,38.52]
["carbon dioxide transport","GO:0015670",0.007971,1,125.2]
["oligosaccharide catabolic process","GO:0009313",0.007971,1,125.2]
["extracellular matrix disassembly","GO:0022617",0.007971,1,125.2]
["hemidesmosome assembly","GO:0031581",0.007971,1,125.2]
["regulation of translation in response to stress","GO:0043555",0.007971,1,125.2]
["regulation of translation initiation in response to stress","GO:0043558",0.007971,1,125.2]
[]
[]
["GOFFA FOR 104 DOWNREGULATED PROTEINS (p < 0.01, E ≥ 2.0)"]
["GO TERM (Biological process)","GO ID","P-VALUE","#PROTEINS","E-VALUE"]
["biosynthetic process","GO:0009058",0.002849,15,2.22]
["cell development","GO:0048468",0.009559,13,2.07]
["catabolic process","GO:0009056",0.000205,12,3.4]
["death","GO:0016265",0.001495,12,2.72]
["cell death","GO:0008219",0.001495,12,2.72]
["programmed cell death","GO:0012501",0.000855,12,2.9]
["apoptosis","GO:0006915",0.000816,12,2.92]
["organic acid metabolic process","GO:0006082",4.7e-05,11,4.33]
["cellular catabolic process","GO:0044248",9.7e-05,11,3.99]
["cellular biosynthetic process","GO:0044249",0.000534,11,3.27]
["nitrogen compound metabolic process","GO:0006807",6.9e-05,10,4.57]
["response to chemical stimulus","GO:0042221",9.7e-05,10,4.38]
["lipid metabolic process","GO:0006629",0.003863,10,2.71]
["cellular lipid metabolic process","GO:0044255",0.000758,10,3.38]
["carboxylic acid metabolic process","GO:0019752",0.000225,10,3.95]
["generation of precursor metabolites and energy","GO:0006091",0.004661,8,3.07]
["amine metabolic process","GO:0009308",0.000924,8,3.99]
["carbohydrate metabolic process","GO:0005975",0.003088,8,3.28]
["amino acid and derivative metabolic process","GO:0006519",0.001496,7,4.17]
["electron transport","GO:0006118",0.001684,7,4.09]
["alcohol metabolic process","GO:0006066",0.00452,6,3.9]
["nucleotide metabolic process","GO:0009117",0.000902,6,5.39]
["amino acid metabolic process","GO:0006520",0.002215,6,4.52]
["nucleotide biosynthetic process","GO:0009165",0.000859,5,6.84]
["negative regulation of programmed cell death","GO:0043069",0.006209,5,4.32]
["negative regulation of apoptosis","GO:0043066",0.006005,5,4.36]
["anti-apoptosis","GO:0006916",0.002367,5,5.43]
["nitrogen compound biosynthetic process","GO:0044271",0.001283,4,8.55]
["protein-RNA complex assembly","GO:0022618",0.002793,4,6.9]
["response to toxin","GO:0009636",0.000108,3,32.85]
["response to protein stimulus","GO:0051789",0.002676,3,10.95]
["vitamin metabolic process","GO:0006766",0.003958,3,9.53]
["heterocycle metabolic process","GO:0046483",0.006576,3,7.93]
["response to unfolded protein","GO:0006986",0.002676,3,10.95]
["nitrogen compound catabolic process","GO:0044270",0.006576,3,7.93]
["water-soluble vitamin metabolic process","GO:0006767",0.001297,3,14.12]
["mitochondrion organization and biogenesis","GO:0007005",0.001502,3,13.41]
["regulation of neurotransmitter levels","GO:0001505",0.008192,3,7.32]
["glutamine family amino acid metabolic process","GO:0009064",0.00114,3,14.77]
["protein oligomerization","GO:0051259",0.004024,3,9.47]
["glycolipid metabolic process","GO:0006664",0.000633,3,18.09]
["sphingolipid metabolic process","GO:0006665",0.003578,3,9.88]
["cholesterol metabolic process","GO:0008203",0.00892,3,7.09]
["fatty acid oxidation","GO:0019395",0.000252,3,24.77]
["glycosphingolipid metabolic process","GO:0006687",0.00024,3,25.15]
["fatty acid beta-oxidation","GO:0006635",6.8e-05,3,38.33]
["aging","GO:0007568",0.007852,2,15.11]
["cell aging","GO:0007569",0.002818,2,25.55]
["nitric oxide metabolic process","GO:0046209",0.00662,2,16.51]
["nucleobase metabolic process","GO:0009112",0.002312,2,28.24]
["microtubule organizing center organization and biogenesis","GO:0031023",0.00397,2,21.46]
["vitamin biosynthetic process","GO:0009110",0.005306,2,18.5]
["centrosome cycle","GO:0007098",0.001964,2,30.66]
["mitochondrial membrane organization and biogenesis","GO:0007006",0.007224,2,15.78]
["nitric oxide biosynthetic process","GO:0006809",0.00662,2,16.51]
["water-soluble vitamin biosynthetic process","GO:0042364",0.003816,2,21.9]
["centrosome organization and biogenesis","GO:0051297",0.00397,2,21.46]
["ribosome assembly","GO:0042255",0.000575,2,56.48]
["glutamine metabolic process","GO:0006541",0.001542,2,34.62]
["protein tetramerization","GO:0051262",0.002818,2,25.55]
["glutamine family amino acid catabolic process","GO:0009065",0.003088,2,24.39]
["cholesterol biosynthetic process","GO:0006695",0.009179,2,13.94]
["apoptotic mitochondrial changes","GO:0008637",0.005668,2,17.89]
["mitochondrial fragmentation during apoptosis","GO:0043653",0.000264,2,82.55]
["activation of NF-kappaB transcription factor","GO:0051092",0.009642,2,13.58]
["cyanate metabolic process","GO:0009439",0.005581,1,178.86]
["one-carbon compound catabolic process","GO:0019754",0.005581,1,178.86]
["cyanate catabolic process","GO:0009440",0.005581,1,178.86]
["negative regulation of oxidoreductase activity","GO:0051354",0.003724,1,268.29]
["mitochondrial genome maintenance","GO:0000002",0.009284,1,107.32]
["fructosamine metabolic process","GO:0030389",0.001864,1,536.58]
["negative regulation of nitric oxide biosynthetic process","GO:0045019",0.009284,1,107.32]
["hypoxanthine metabolic process","GO:0046100",0.003724,1,268.29]
["negative regulation of nitric-oxide synthase activity","GO:0051001",0.003724,1,268.29]
["positive regulation of catecholamine metabolic process","GO:0045915",0.003724,1,268.29]
["heme oxidation","GO:0006788",0.007434,1,134.15]
["fructoselysine metabolic process","GO:0030393",0.001864,1,536.58]
["NADP biosynthetic process","GO:0006741",0.001864,1,536.58]
["glutamine catabolic process","GO:0006543",0.005581,1,178.86]
["positive regulation of dopamine metabolic process","GO:0045964",0.003724,1,268.29]