{"text_format":"2","workbook":"xls","n_sheets":3,"sheets":["EGFR","FGFR1","IGF1R"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":0,"defined_names":0,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"EGFR","index":0,"n_rows":140,"n_cols":19,"rows_kept":140,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["Table S1. Equilibrium dissociation constants for interactions between SH2/PTB domains and phosphopeptides."]
["All dissociation constants have the units nM. 'Nonphysiological' phosphopeptides are colored green; 'physiological' phosphopeptides are colored red."]
["Peptides derived from EGFR are on the first sheet; peptides derived from FGFR1 are on the second sheet; peptides derived from IGF1R are on the third sheet."]
[]
[null,"EGFR 727","EGFR 764","EGFR 801","EGFR 813","EGFR 827","EGFR 869","EGFR 891","EGFR 915","EGFR 978","EGFR 998","EGFR 1016","EGFR 1069","EGFR 1092","EGFR 1110","EGFR 1125","EGFR 1138","EGFR 1172","EGFR 1197"]
["SH2 domains"]
["PIK3R1-N",{"$nulls":10},899.24885314949,null,1075.15474442679,null,null,null,403.799265185721,500]
["PIK3R1-C",null,null,null,1849,{"$nulls":6},873]
["PIK3R1-NC",null,null,null,1820,{"$nulls":5},239.015054428716,175.2946577053227,null,669.893962901303,null,null,1568.51683927852,546.511578803695,500]
["PIK3R3-N",{"$nulls":10},721.6822918942476,null,506.639404500492,null,null,838.00703664999]
["PIK3R3-C",{"$nulls":10},193]
["PIK3R3-NC",null,null,null,1868,{"$nulls":5},967.50446846252,203.4486993107475,null,1023.82886951715,null,null,1688.22266684751,850.372684539283,805]
["PIK3R2-N",{"$nulls":10},424.26548343745253,null,453.278410264928,null,null,763.337531196943,389.701373150743,500]
["PIK3R2-C"]
["PIK3R2-NC",{"$nulls":10},352,null,1405.54034406735,null,null,857.495201246876,321.987493130263]
["DAPP1"]
["ABL2",null,null,null,201,null,1083.3322560474503,null,177.2665089005983,null,1498.16585668803,282,null,151.652660087262,62,74.13003225767258,119.9041688116765,338.1141142541215,214]
["ABL1",{"$nulls":12},915.646885589665,523]
["FGR",{"$nulls":16},546.273497905472,617.794208165056]
["SRC",578.712904705548,null,null,84.2745291083718,{"$nulls":5},1139.07961141916,null,null,1789.38384030512,null,null,null,465.955013837096,380.524106712732]
["SLA2"]
["ZAP70-N"]
["ZAP70-C"]
["ZAP70-NC",{"$nulls":9},1653,{"$nulls":5},1137.48956720548]
["BMX",{"$nulls":14},1067]
["SYK-N",819.413964387176,null,559.4,{"$nulls":14},294.484099579673]
["SYK-C",{"$nulls":10},934,null,1923.95875852024,null,null,null,869.335000847784]
["SYK-NC",null,null,null,240.250352420949,null,null,null,1549,null,905,610.6347288107605,null,908.027130617417,null,981,null,832.8725122690455,379.666452498866]
["TEC",{"$nulls":17},480.179145756906]
["LYN",{"$nulls":16},1590.08923109125,171.427515776908]
["BLK",{"$nulls":5},1708,null,1177.1201064142228,null,190.833620232159,658.479438876326,null,300.461922692449,null,null,null,750.65892107193,500]
["ITK",null,null,null,310.386796707764,{"$nulls":5},277.173844435226,null,null,219.373711958644,null,null,1758.39066491723,1410.05167416185,500]
["BTK"]
["TXK"]
["FER"]
["HCK"]
["PTK6"]
["LCK"]
["FES",{"$nulls":9},1234]
["YES1",539.599644902124,null,null,21.6382683110674,null,null,null,327.9903658618722,null,723.707336899252,null,295.0661337421614,336.708406127483,null,378.28192268389154,null,97.7122926194313,127.493265092289]
["MATK"]
["PLCG1-N"]
["PLCG1-C"]
["PLCG1-NC",{"$nulls":10},794]
["PLCG2-N",{"$nulls":16},840.78303815252]
["PLCG2-C"]
["PLCG2-NC",{"$nulls":9},1390.613425544875,null,null,1632.70724479346,null,null,null,674.385395331721,500]
["GRB2",{"$nulls":12},198.117736042551,null,null,422.29447532285303,null,415.202227046227]
["GRB7",null,null,null,456.278981938874,{"$nulls":5},755.357341487024,null,null,1984.84119486762,null,null,null,827.736772914381,500]
["GRB10",null,null,null,352.767365399334,{"$nulls":5},1685.73111994097,null,null,1296.35997958869,null,null,null,1292.53461489387]
["GRB14",{"$nulls":16},1248.87719870046]
["GRAP2"]
["CRK",{"$nulls":10},470,null,null,null,1234,null,408.185647098872,1070.11504627443]
["CRKL",{"$nulls":10},998.141411313546,{"$nulls":6},1338.7955107781]
["NCK1",{"$nulls":10},1004]
["NCK2",null,null,null,195,{"$nulls":8},1099.79147828546,null,null,326.10452593101,380.188220652053]
["PTPN11-N",{"$nulls":10},379]
["PTPN11-C"]
["PTPN11-NC"]
["APS"]
["SH3BP2"]
["LNK",{"$nulls":9},1362,{"$nulls":6},1599.57022205336]
["SH2B",{"$nulls":16},1817.249558384]
["SHC1",{"$nulls":17},776.568439195454]
["SHC3",{"$nulls":10},216,{"$nulls":6},1032.70343275893]
["JAK2",{"$nulls":10},1944]
["JAK3",{"$nulls":16},1561.56176441243]
["BRDG1"]
["LCP2"]
["BLNK"]
["RIN1"]
["SH2D3A"]
["CHN2"]
["RASA1-N",{"$nulls":7},1407.333652754902,null,709.2977428179245,487.788428930194,null,179.618845248452,null,1319,388.000903965588,588.7891407731437,707.515628019644]
["RASA1-C",null,null,null,1950]
["RASA1-NC",null,null,null,154.761733331476,{"$nulls":5},1651.799703353845,1417,{"$nulls":5},1166.52859106261,500]
["BCAR3",{"$nulls":16},299.737968472334]
["SH2D2A"]
["SH2D3C",null,null,null,51.7903193686054,{"$nulls":12},1913.13270789884]
["VAV1",null,null,null,373.443842555998,{"$nulls":6},1046]
["VAV2",null,null,null,472,{"$nulls":6},85.4236121653889,null,542.045794297655,null,null,372.911967637152,215.921893616468]
["VAV3",null,null,null,960]
["PTPN6-C"]
["PTPN6-N"]
["PTPN6-NC"]
["E18941"]
["HSH2D",{"$nulls":6},1128.19896966914]
["CTEN",{"$nulls":6},298.502381154648,null,null,null,922,{"$nulls":5},333.980956829447]
["E109111",{"$nulls":16},1031.05409077189]
["E138606",null,null,null,1060]
["E169291",null,null,null,1376]
["E105251"]
["SHB",null,null,null,275.647713403648,null,null,null,1058.8247645460285,null,null,1991.32342490441,862.0775068407271,null,null,991.452040125739,null,1791.39005739861]
["TNS",{"$nulls":14},1283.2391560172343]
["TENC1",null,null,null,1145]
["TENS1",null,null,null,1887,{"$nulls":12},735.665063440736]
["SH2D1A"]
["INPPL1"]
["EAT2",null,null,null,1600]
["CBL"]
["STAT1",null,null,null,1455,{"$nulls":12},1067.18381084819,318.253911204962]
["STAT2",{"$nulls":12},1625.93532429108,null,null,null,1375.09436836813]
["PTB domains"]
["APBB1-N",null,null,null,1797,{"$nulls":12},1069.62268763195]
["APBB1-C",{"$nulls":9},1500,788]
["APBB1-NC",{"$nulls":9},1500,647,{"$nulls":5},844.379956722831]
["APBB2-N",{"$nulls":9},1500]
["APBB2-C",{"$nulls":6},669.294605100302]
["APBB2-NC",null,null,null,458,{"$nulls":5},1568,1597]
["APBB3-N"]
["APBB3-C"]
["APBB3-NC",null,null,null,1277,{"$nulls":5},1620,1633]
["APBA1"]
["APBA3",{"$nulls":10},577]
["APBA2"]
["DAB1"]
["DAB2"]
["NUMBL",null,null,null,1843,{"$nulls":5},1500]
["NUMB",{"$nulls":6},486,null,null,null,748]
["E129946",{"$nulls":9},978,664,{"$nulls":5},1222.8630472547]
["SHC1-PTB",null,null,null,1498,{"$nulls":5},1152,628,null,null,321,null,172.540496412692,78.4608954068685,337.424640060527]
["DOK1",{"$nulls":16},1690.45565759088]
["DOK2"]
["DOK4",null,null,null,1348.04570108372,{"$nulls":6},886]
["DOK5",{"$nulls":10},1000]
["IRS1",{"$nulls":9},1500,{"$nulls":6},1282.47358600453]
["IRS4",{"$nulls":9},1809,808]
["FRS3"]
["RABGAP1",null,null,null,1809.45586579947]
["ANKS1",{"$nulls":9},800,931,{"$nulls":5},770.101796993318,38.5246953764294]
["APPL",{"$nulls":9},1640,1161,{"$nulls":5},1277.8842308473]
["GULP1",{"$nulls":14},813.1527737225649,null,1993.64301450343]
["EPS8L2"]
["SHC3-PTB"]
["TNS-PTB"]
["TENC1-PTB",{"$nulls":16},1403.89339530038]
["CCM2"]
["RABGAP1L"]
["EB-1",{"$nulls":10},519]
["DOK5L",{"$nulls":9},1836,735,{"$nulls":5},1229.88883830482]

{"sheet":"FGFR1","index":1,"n_rows":140,"n_cols":12,"rows_kept":140,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["Supplementary Table 1. Equilibrium dissociation constants for interactions between SH2/PTB domains and phosphopeptides."]
["All dissociation constants have the units nM. 'Nonphysiological' phosphopeptides are colored green; 'physiological' phosphopeptides are colored red."]
["Peptides derived from EGFR are on the first sheet; peptides derived from FGFR1 are on the second sheet; peptides derived from IGF1R are on the third sheet."]
[]
[null,"FGFR1 463","FGFR1 563","FGFR1 572","FGFR1 583","FGFR1 585","FGFR1 605","FGFR1 654","FGFR1 701","FGFR1 730","FGFR1 766","FGFR1 776"]
["SH2 domains"]
["PIK3R1-N",{"$nulls":8},220.55784045960513]
["PIK3R1-C"]
["PIK3R1-NC",{"$nulls":7},324.935346794665,167.69833463055096]
["PIK3R3-N",{"$nulls":8},266.41001640683544,1105]
["PIK3R3-C"]
["PIK3R3-NC",{"$nulls":7},617.868753967486,123.9550842511223]
["PIK3R2-N",{"$nulls":8},94.5735069876814]
["PIK3R2-C"]
["PIK3R2-NC",{"$nulls":8},140.5464349650986]
["DAPP1"]
["ABL2",63.99948194673006,null,null,335.179821016104,274.137197066824,11.8824570506397,1324.55240136128,399.282981316352,null,null,851.160372688983]
["ABL1",null,null,null,1840.9364528693,null,327.024523387698]
["FGR"]
["SRC",328.6838006539193,null,null,null,418.148402352217,null,null,1786.08285888392]
["SLA2",{"$nulls":7},1324.9315097668]
["ZAP70-N"]
["ZAP70-C"]
["ZAP70-NC",null,null,null,522.58998137112,1744.06418793169,null,null,420.615170999054,382.68685300599066]
["BMX"]
["SYK-N",1599.3595902776656,null,null,null,1988.67640095763,null,null,793.226740791014,371.95144338774514]
["SYK-C",{"$nulls":4},1535.35094981571]
["SYK-NC",244.9837284674389,null,null,null,1921.77541175652,908.829584639239]
["TEC",{"$nulls":5},354.316958423186,null,384.614891446156]
["LYN",{"$nulls":4},1509.6590528412,null,null,1777.3887665209]
["BLK",144.9824486769756,null,null,null,256.979111695319,null,null,183.251237588841,171.8558459108165]
["ITK",null,null,null,964.501221165821,1391.31300290396,null,null,425.885918788714,96.36608169913069]
["BTK"]
["TXK",{"$nulls":7},750.382367716111]
["FER"]
["HCK"]
["PTK6"]
["LCK"]
["FES"]
["YES1",453.3128039313407,null,null,1547.3040056705,1016.04626527699,null,null,756.260008124066,280.8695986679313,null,1359.71739352135]
["MATK"]
["PLCG1-N",{"$nulls":9},1829]
["PLCG1-C"]
["PLCG1-NC"]
["PLCG2-N",{"$nulls":7},1417.21134998079,230.1610950143319]
["PLCG2-C"]
["PLCG2-NC",390.93234860683776,null,null,1224.26404993775,1398.38503852336,1415.71381771713,null,684.431505424697,332.2166128212239,1465]
["GRB2",334.8777396841363,null,null,1620.30602158229,null,null,null,143.276907299727]
["GRB7",null,null,null,998.203936389363,null,null,null,651.219406285658]
["GRB10",{"$nulls":4},1870.06126192979,null,null,791.020840428257,389.95782277562114]
["GRB14"]
["GRAP2",{"$nulls":6},1082.33347621477]
["CRK",{"$nulls":5},259.549746656535,1109.06428237235,1072.11550538224]
["CRKL",null,null,null,1548.75396326722,1821.66331574697,238.894761409322]
["NCK1"]
["NCK2",284.8448471126652,null,null,1382.05470458884,1298.25967203711,726.566323687824]
["PTPN11-N"]
["PTPN11-C"]
["PTPN11-NC"]
["APS",{"$nulls":7},1802.82081869381]
["SH3BP2",{"$nulls":4},1604.90621646477,null,null,780.499867713318]
["LNK",{"$nulls":7},667.171178578814]
["SH2B",672.1000851413467,{"$nulls":6},522.293577586495]
["SHC1"]
["SHC3"]
["JAK2",{"$nulls":7},681.558034002973]
["JAK3",665.8901273689955,null,null,null,1107.59997009666,null,null,386.754601082969]
["BRDG1"]
["LCP2"]
["BLNK"]
["RIN1",1274.2532742125002]
["SH2D3A"]
["CHN2"]
["RASA1-N",174.8873681704119,null,null,1945.16354018111,{"$nulls":6},1807.64183646858]
["RASA1-C"]
["RASA1-NC",246.11766841881825,null,null,null,1099.65891951308,null,null,79.4168193541471]
["BCAR3",242.4933944810707,null,null,null,1764.84935718235,null,null,578.725073785017]
["SH2D2A"]
["SH2D3C",769.8990900328489,null,null,1488.5658523599,1511.2537474598,null,null,1225.49081357344]
["VAV1"]
["VAV2",16.69320502295661,{"$nulls":4},61.792404894524]
["VAV3"]
["PTPN6-C"]
["PTPN6-N",472.2108756534329,{"$nulls":6},676.375681412415]
["PTPN6-NC"]
["E18941"]
["HSH2D",{"$nulls":4},1678.94800484959]
["CTEN"]
["E109111",{"$nulls":7},703.042027289288]
["E138606",191.1749630716074,null,null,null,780.236706144827]
["E169291"]
["E105251"]
["SHB",{"$nulls":4},959.721845584769,null,null,627.83028513878]
["TNS",{"$nulls":4},1916.72936647746]
["TENC1"]
["TENS1",{"$nulls":7},572.725338819635]
["SH2D1A"]
["INPPL1"]
["EAT2",{"$nulls":4},1655.57159856697]
["CBL"]
["STAT1",1435.8599298843083,{"$nulls":6},512.637533690932,248.74349180254003]
["STAT2",168.61454194708153,null,null,null,401.052439072544,null,null,110.860732327261]
["PTB domains"]
["APBB1-N"]
["APBB1-C"]
["APBB1-NC",{"$nulls":4},1649.00875728885,null,null,987.810470272286]
["APBB2-N",null,null,null,1157.27118788584]
["APBB2-C"]
["APBB2-NC"]
["APBB3-N"]
["APBB3-C",{"$nulls":4},1717.33888775296]
["APBB3-NC"]
["APBA1"]
["APBA3"]
["APBA2"]
["DAB1"]
["DAB2"]
["NUMBL",{"$nulls":7},1219.23782730029]
["NUMB",{"$nulls":9},1688]
["E129946",226.09133200693276,{"$nulls":6},307.358048134923]
["SHC1-PTB",{"$nulls":8},69.58226507645142]
["DOK1",544.4458972244798,{"$nulls":6},523.266008075105]
["DOK2"]
["DOK4",{"$nulls":7},772.893424758907]
["DOK5"]
["IRS1",{"$nulls":7},1349.67250686885]
["IRS4"]
["FRS3"]
["RABGAP1"]
["ANKS1",264.1331875722145,null,null,null,424.609209185838,1826.80245034858,null,206.652832364177]
["APPL"]
["GULP1",136.0800886966747,null,null,null,536.615784130492,null,null,269.909771543169]
["EPS8L2",{"$nulls":4},1944.21008341464]
["SHC3-PTB"]
["TNS-PTB"]
["TENC1-PTB",{"$nulls":7},1849.36903839846]
["CCM2"]
["RABGAP1L"]
["EB-1",{"$nulls":7},365.046335864461]
["DOK5L",{"$nulls":7},1782.17992220302]

{"sheet":"IGF1R","index":2,"n_rows":140,"n_cols":14,"rows_kept":140,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["Supplementary Table 1. Equilibrium dissociation constants for interactions between SH2/PTB domains and phosphopeptides."]
["All dissociation constants have the units nM. 'Nonphysiological' phosphopeptides are colored green; 'physiological' phosphopeptides are colored red."]
["Peptides derived from EGFR are on the first sheet; peptides derived from FGFR1 are on the second sheet; peptides derived from IGF1R are on the third sheet."]
[]
[null,"IGF1R 973","IGF1R 980","IGF1R 987","IGF1R 1041","IGF1R 1090","IGF1R 1125","IGF1R 1161","IGF1R 1166","IGF1R 1192","IGF1R 1213","IGF1R 1280","IGF1R 1281","IGF1R 1346"]
["SH2 domains"]
["PIK3R1-N",{"$nulls":12},1758.35736600852]
["PIK3R1-C"]
["PIK3R1-NC",{"$nulls":11},675.206745857661,662.36348171902]
["PIK3R3-N",{"$nulls":12},1524.96555661999]
["PIK3R3-C"]
["PIK3R3-NC",{"$nulls":11},1078.19043116978,600.969848125813]
["PIK3R2-N",{"$nulls":12},588.07865345687]
["PIK3R2-C"]
["PIK3R2-NC"]
["DAPP1"]
["ABL2",48.1752898418802,null,null,102.541453329199,{"$nulls":6},149.49279125526,1434.43611787833,1363.76099024787]
["ABL1"]
["FGR"]
["SRC",{"$nulls":10},286.003600911935,1015.16274284233]
["SLA2",{"$nulls":11},511.575513981341]
["ZAP70-N"]
["ZAP70-C"]
["ZAP70-NC",null,806.0516312139231,{"$nulls":8},1585.28778205799]
["BMX"]
["SYK-N",{"$nulls":6},1173.92817470046,null,null,null,1666.09064318703,813.849158163061]
["SYK-C",{"$nulls":10},362.173238329312]
["SYK-NC",null,null,973.62749612864]
["TEC",{"$nulls":10},671.4149350737805,1882.22223705604]
["LYN",{"$nulls":10},767.68981085967,1203.39645086689]
["BLK",{"$nulls":6},1795.34230278059,null,1147.7,null,256.99605970095,576.619996205328]
["ITK",{"$nulls":6},1516.29167293055,null,null,null,175.5361788534435,509.058012171314]
["BTK"]
["TXK"]
["FER"]
["HCK"]
["PTK6"]
["LCK"]
["FES"]
["YES1",{"$nulls":6},775.022213282878,null,487.538438704822,null,461.465186513608,488.90522474994]
["MATK",null,null,1219]
["PLCG1-N"]
["PLCG1-C"]
["PLCG1-NC",{"$nulls":11},1786.3508883637]
["PLCG2-N",{"$nulls":7},1597.058376]
["PLCG2-C"]
["PLCG2-NC",{"$nulls":10},447.707218582459,275.863668210805]
["GRB2"]
["GRB7",null,null,857.666440262766,{"$nulls":7},483.1864691305645,1130.35904546156]
["GRB10",{"$nulls":10},302.179274513963]
["GRB14",{"$nulls":10},565.428945961639]
["GRAP2"]
["CRK"]
["CRKL",1863.02579141212,{"$nulls":6},1830.091014]
["NCK1"]
["NCK2",349.093969885648]
["PTPN11-N"]
["PTPN11-C"]
["PTPN11-NC"]
["APS"]
["SH3BP2",{"$nulls":10},749.482924013908,558.780687901687]
["LNK",{"$nulls":11},785.675482429429]
["SH2B",{"$nulls":11},1215.90161619386]
["SHC1"]
["SHC3"]
["JAK2",{"$nulls":11},1806.13385912115]
["JAK3",{"$nulls":10},524.469542985934,382.555677042211]
["BRDG1"]
["LCP2"]
["BLNK"]
["RIN1"]
["SH2D3A"]
["CHN2",{"$nulls":11},1746.46664707025]
["RASA1-N",{"$nulls":6},1225.3194551381366,null,null,null,343.484742639186,1282.91295275105]
["RASA1-C"]
["RASA1-NC",{"$nulls":8},1151.00452298051,null,335.421681340477]
["BCAR3",null,null,1945.4678053641,{"$nulls":7},1054.41829300399]
["SH2D2A"]
["SH2D3C",{"$nulls":10},336.36657354126]
["VAV1"]
["VAV2",{"$nulls":6},1144.24224660991]
["VAV3"]
["PTPN6-C"]
["PTPN6-N",{"$nulls":10},1308.016469561032]
["PTPN6-NC"]
["E18941"]
["HSH2D"]
["CTEN",null,null,284.101596505679]
["E109111"]
["E138606",{"$nulls":10},321.271887514023,868.290930570663]
["E169291"]
["E105251"]
["SHB",{"$nulls":10},313.391191903124]
["TNS"]
["TENC1"]
["TENS1",{"$nulls":11},1236.75767532561]
["SH2D1A"]
["INPPL1"]
["EAT2"]
["CBL",{"$nulls":10},981.2533795902815,392.353907582994]
["STAT1",null,null,1679.50363578014,null,null,null,1381.85103903444,null,null,null,598.190840241222,363.78972145771]
["STAT2",{"$nulls":10},519.7522350192125,182.837836003047]
["PTB domains"]
["APBB1-N"]
["APBB1-C"]
["APBB1-NC",{"$nulls":11},1411.73043138048]
["APBB2-N"]
["APBB2-C"]
["APBB2-NC"]
["APBB3-N"]
["APBB3-C"]
["APBB3-NC"]
["APBA1"]
["APBA3"]
["APBA2"]
["DAB1"]
["DAB2"]
["NUMBL"]
["NUMB",null,null,162.395435818654]
["E129946",{"$nulls":11},526.404132621081]
["SHC1-PTB",null,80]
["DOK1",{"$nulls":10},1057.116712027101]
["DOK2",{"$nulls":11},1348.3308239371]
["DOK4"]
["DOK5"]
["IRS1"]
["IRS4"]
["FRS3"]
["RABGAP1"]
["ANKS1",{"$nulls":10},370.47976288979,199.350068266398]
["APPL",{"$nulls":11},289.481397673511]
["GULP1",{"$nulls":10},296.410358332039,285.077246777587]
["EPS8L2"]
["SHC3-PTB"]
["TNS-PTB"]
["TENC1-PTB",{"$nulls":10},650.28904402942,692.472866598232]
["CCM2"]
["RABGAP1L"]
["EB-1",{"$nulls":11},554.692024228144]
["DOK5L",{"$nulls":11},693.890545594532]