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["Probe.Set.ID","GENE_TITLE","GENE_SYMBOL",null,"SYSTEMATIC_ID","adj.p.values..0vs.30","Fold-Change..0vs.30","adj.p.values..0vs.60","Fold-Change..0vs.60","adj.p.values..0vs.120","Fold-Change..0vs.120"]
["5915_at","Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock","STL1","YDR536w","YDR536W",0.001358348,11.22,8.6e-05,25.41,6.96e-05,25.12]
["10689_at","Cell wall mannoprotein, linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; involved in cell wall organization; required for propionic acid resistance","CWP1","YKL096w","YKL096W",0.003561777,3.4,8.6e-05,7.12,6.96e-05,7.58]
["9958_at","Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism; undergoes either proteasome-mediated or autophagy-mediated degradation depending on growth conditions; interacts with Vid30p","FBP1","YLR377c","YLR377C",0.020320877,4.12,0.002181279,6.73,0.002875174,6.53]
["4978_at","Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation","FMP48","YGR052w","YGR052W",null,null,0.006657839,5.96,0.008334269,5.82]
["11185_at","Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element","INO1","YJL153c","YJL153C",0.018287791,4.56,0.00226988,6.42,0.00351733,5.78]
["4431_at","---","---","YHR095w","YHR095W",null,null,0.005476835,8.52,0.013213823,5.6]
["7477_at","---","---","snR45","SNR45",null,null,0.016222555,2.47,0.003661916,5.4]
["8664_at","2'-O-methyltransferase responsible for modification of tRNA at position 4; exhibits no obvious similarity to other known methyltransferases","TRM13","YOL125w","YOL125W",null,null,0.003172797,4.88,0.003748752,4.88]
["8408_at","Protein of unknown function; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport","PNS1","YOR161c","YOR161C",null,null,0.00226988,5.36,0.003613475,4.86]
["9481_at","Cytoplasmic aldehyde dehydrogenase, involved in beta-alanine synthesis; uses NAD+ as the preferred coenzyme; very similar to Ald2p; expression is induced by stress and repressed by glucose","ALD3","YMR169c","YMR169C",null,null,0.00226988,5.24,0.003794405,4.45]
["11114_at","Ornithine carbamoyltransferase (carbamoylphosphate:L-ornithine carbamoyltransferase), catalyzes the sixth step in the biosynthesis of the arginine precursor ornithine","ARG3","YJL088w","YJL088W",null,null,0.00226988,4.88,0.003748752,4.32]
["6234_at","Transcriptional corepressor involved in the regulation of ribosomal protein gene transcription via the TOR signaling pathway and protein kinase A, phosphorylated by activated Yak1p which promotes accumulation of Crf1p in the nucleus","CRF1","YDR223w","YDR223W",null,null,0.011786537,3.82,0.014404673,3.68]
["6233_at","---","---","YDR222w","YDR222W",null,null,0.003748165,4.59,0.007691357,3.62]
["8663_at","Cytoplasmic malate dehydrogenase, one of three isozymes that catalyze interconversion of malate and oxaloacetate; involved in the glyoxylate cycle and gluconeogenesis during growth on two-carbon compounds; interacts with Pck1p and Fbp1","MDH2","YOL126c","YOL126C",0.020320877,2.56,0.002086046,3.75,0.002875174,3.55]
["5913_at","Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall","FIT1","YDR534c","YDR534C",null,null,0.002084857,3.53,0.00213881,3.52]
["10934_at","Mitochondrial succinate-fumarate transporter, transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization","SFC1","YJR095w","YJR095W",0.020320877,2.83,0.00226988,3.72,0.003661916,3.45]
["10058_at","Zinc finger transcription factor involved in the complex regulation of gene expression in response to levels of heme and oxygen; the S288C sequence differs from other strain backgrounds due to a Ty1 insertion in the carboxy terminus","HAP1","YLR256w","YLR256W",0.039594892,2.08,0.002086046,3.29,0.002621391,3.28]
["5173_at","Transcription factor of the Zn[II]2Cys6 family involved in sterol uptake; involved in induction of hypoxic gene expression","SUT1","YGL162w","YGL162W",null,null,0.003172797,3.38,0.004303769,3.19]
["8192_at","Proline permease, required for high-affinity transport of proline; also transports the toxic proline analog azetidine-2-carboxylate (AzC); PUT4 transcription is repressed in ammonia-grown cells","PUT4","YOR348c","YOR348C",null,null,0.002181279,3.66,0.00351733,3.18]
["8659_at","Protein of unknown function, expression is regulated by phosphate levels; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole","PHM7","YOL084w","YOL084W",null,null,0.016103525,3.68,0.025299251,3.17]
["4423_at","Protein of unknown function involved in RNA metabolism; has structural similarity to SBDS, the human protein mutated in Shwachman-Diamond Syndrome (the yeast SBDS ortholog = SDO1); null mutation suppresses cdc13-1 temperature sensitivity","RTC3","YHR087w","YHR087W",null,null,0.006294028,3.24,0.008070919,3.14]
["4866_at","Ammonium permease; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation","MEP1","YGR121c","YGR121C",null,null,0.003748165,3,0.004497689,3.1]
["5636_at","Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose","ICL1","YER065c","YER065C",null,null,0.006657839,3.15,0.00856948,3.07]
["8864_at","Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids","ACC1","YNR016c","YNR016C",null,null,0.003748165,3.21,0.005948845,3.04]
["10183_at","Acetyl-coA synthetase isoform which, along with Acs1p, is the nuclear source of acetyl-coA for histone acetylation; mutants affect global transcription; required for growth on glucose; expressed under anaerobic conditions","ACS2","YLR153c","YLR153C",null,null,0.014623965,3.32,0.022096504,3.02]
["7254_at","Transketolase, similar to Tkl1p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids","TKL2","YBR117c","YBR117C",null,null,0.003748165,3.29,0.006178902,2.94]
["4924_at","Cytosolic catalase T, has a role in protection from oxidative damage by hydrogen peroxide","CTT1","YGR088w","YGR088W",null,null,0.00526164,3.15,0.00789221,2.93]
["8147_s_at","Putative protein of unknown function /// Putative protein of unknown function","PAU21 /// PAU22","YOR394w","YOR394W",null,null,0.011433553,4.35,0.028325824,2.92]
["6082_at","Plasma membrane protein, regulation pattern suggests a possible role in export of ammonia from the cell; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family of putative transporters","ATO3","YDR384c","YDR384C",0.018287791,2.52,0.00226988,3.05,0.00351733,2.91]
["4948_at","---","---","YGR067c","YGR067C",null,null,0.006657839,3.3,0.011678218,2.91]
["3145_at","---","---","Unknown","YILCDELTA5",null,null,0.011433553,2.86,0.011694316,2.89]
["5725_at","---","---","YEL020c","YEL020C",null,null,0.014483621,2.82,0.01714258,2.86]
["10703_at","Protein required for transcription of rDNA by RNA polymerase I; transcription factor independent of DNA template; involved in recruitment of RNA polymerase I to rDNA","RRN3","YKL125w","YKL125W",null,null,0.00526164,2.85,0.006393557,2.86]
["6936_g_at","Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources","GLK1","YCL042w","YCL042W",null,null,0.018646829,4.23,0.049340285,2.84]
["8546_at","Basic leucine zipper (bZIP) transcription factor of the yAP-1 family, mediates pleiotropic drug resistance and salt tolerance; nuclearly localized under oxidative stress and sequestered in the cytoplasm by Lot6p under reducing conditions","CIN5","YOR028c","YOR028C",null,null,0.007858818,3.33,0.014404673,2.81]
["9905_at","---","---","YLR414c","YLR414C",null,null,0.038345143,2.45,0.032054007,2.77]
["9724_at","One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae","HMG1","YML075c","YML075C",null,null,0.004507823,2.81,0.006150739,2.76]
["10511_at","General amino acid permease; localization to the plasma membrane is regulated by nitrogen source","GAP1","YKR039w","YKR039W",null,null,0.008757168,2.45,0.007345175,2.74]
["7807_at","Plasma membrane H+-ATPase, isoform of Pma1p, involved in pumping protons out of the cell; regulator of cytoplasmic pH and plasma membrane potential","PMA2","YPL036w","YPL036W",null,null,0.006657839,2.82,0.008874912,2.74]
["4759_at","Peroxin required for targeting of peroxisomal matrix proteins containing PTS2; interacts with Pex7p; partially redundant with Pex18p","PEX21","YGR239c","YGR239C",null,null,0.03844212,2.54,0.037576444,2.71]
["4867_at","---","---","YGR122w","YGR122W",null,null,0.004574514,2.78,0.006256071,2.7]
["6694_at","Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor","PRR2","YDL214c","YDL214C",null,null,0.011981552,2.65,0.013976484,2.65]
["9997_at","Nicotinic acid mononucleotide adenylyltransferase, involved in pathways of NAD biosynthesis, including the de novo, NAD(+) salvage, and nicotinamide riboside salvage pathways","NMA1","YLR328w","YLR328W",null,null,0.003306089,2.72,0.004504497,2.64]
["4507_at","---","---","YHR033w","YHR033W",null,null,0.00526164,2.77,0.007641272,2.64]
["7313_at","Meiosis-specific regulatory subunit of the Glc7p protein phosphatase, regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p","GIP1","YBR045c","YBR045C",null,null,0.026264263,3.07,0.04439755,2.62]
["4804_at","Xylulokinase, converts D-xylulose and ATP to xylulose 5-phosphate and ADP; rate limiting step in fermentation of xylulose; required for xylose fermentation by recombinant S. cerevisiae strains","XKS1","YGR194c","YGR194C",null,null,0.003306089,2.64,0.004303769,2.57]
["11135_at","Peripheral protein of the cytosolic face of the mitochondrial outer membrane, required for mitochondrial fission; interacts with Fis1p and with the dynamin-related GTPase Dnm1p; contains WD repeats","MDV1","YJL112w","YJL112W",null,null,0.005316067,2.55,0.006489494,2.56]
["7070_at","MAL-activator protein, part of complex locus MAL3; nonfunctional in genomic reference strain S288C","MAL33","YBR297w","YBR297W",null,null,0.013651473,3.04,0.025053909,2.56]
["7253_g_at","Transketolase, similar to Tkl1p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids","TKL2","YBR116c","YBR116C",null,null,0.003527846,2.76,0.005948845,2.55]
["9064_at","---","---","YNL195c","YNL195C",null,null,0.015782712,2.78,0.023536323,2.52]
["5648_at","Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm","PTP3","YER075c","YER075C",null,null,0.011065401,2.37,0.009702807,2.51]
["10154_at","Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose","IDP2","YLR174w","YLR174W",null,null,0.005399114,2.64,0.008070919,2.48]
["10182_at","---","---","YLR152c","YLR152C",null,null,0.008043333,2.61,0.011678218,2.45]
["7738_at","Nuclear protein proposed to regulate utilization of nonfermentable carbon sources and endocytosis of plasma membrane proteins; overproduction suppresses chs5 spa2 lethality at high temp; ubiquitinated by Rsp5p, deubiquitinated by Ubp2p","CSR2","YPR030w","YPR030W",null,null,0.007521881,2.56,0.010493306,2.44]
["9801_at","---","---","YML131w","YML131W",null,null,0.023165263,2.29,0.02320247,2.43]
["11139_at","Pheromone-regulated protein, predicted to have 5 transmembrane segments; induced by treatment with 8-methoxypsoralen and UVA irradiation","PRM10","YJL108c","YJL108C",null,null,0.044571914,2.35,0.046787612,2.41]
["9902_at","High-affinity copper transporter of the plasma membrane, acts as a trimer; gene is disrupted by a Ty2 transposon insertion in many laboratory strains of S. cerevisiae","CTR3","YLR411w","YLR411W",null,null,0.017260492,2.49,0.022513641,2.4]
["9065_at","---","---","YNL194c","YNL194C",null,null,0.023557536,2.87,0.04467064,2.4]
["7758_at","2-methylisocitrate lyase of the mitochondrial matrix, functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol","ICL2","YPR006c","YPR006C",null,null,0.011065401,2.29,0.010493306,2.39]
["6907_at","Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p)","AGP1","YCL025c","YCL025C",null,null,0.006332554,2.33,0.007345175,2.39]
["4578_at","Major component of the proteasome; tethers the proteasome core particle to the regulatory particle, and enhances the stability of the proteasome","ECM29","YHL030w","YHL030W",null,null,0.003306089,2.74,0.006256071,2.38]
["7318_at","Regulatory subunit of the Glc7p type-1 protein phosphatase; involved with Reg1p, Glc7p, and Snf1p in regulation of glucose-repressible genes, also involved in glucose-induced proteolysis of maltose permease","REG2","YBR050c","YBR050C",null,null,0.004176672,2.46,0.006150739,2.37]
["5381_at","Proteasome activator subunit; found in association with core particles, with and without the 19S regulatory particle; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200","BLM10","YFL007w","YFL007W",null,null,0.023692999,2.88,0.047560368,2.37]
["11356_at","Acetyl-coA synthetase isoform which, along with Acs2p, is the nuclear source of acetyl-coA for histone acetlyation; expressed during growth on nonfermentable carbon sources and under aerobic conditions","ACS1","YAL054c","YAL054C",null,null,0.007749853,2.51,0.011678218,2.36]
["9482_g_at","Cytoplasmic aldehyde dehydrogenase, involved in ethanol oxidation and beta-alanine biosynthesis; uses NAD+ as the preferred coenzyme; expression is stress induced and glucose repressed; very similar to Ald3p /// Cytoplasmic aldehyde dehydrogenase, involved in beta-alanine synthesis; uses NAD+ as the preferred coenzyme; very similar to Ald2p; expression is induced by stress and repressed by glucose","ALD2 /// ALD3","YMR169c","YMR169C",null,null,0.006438455,2.71,0.011694316,2.36]
["10023_at","Chitin deacetylase, together with Cda1p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall","CDA2","YLR308w","YLR308W",null,null,0.022983344,2.82,0.04284326,2.36]
["7982_at","Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","FMP40","YPL222w","YPL222W",null,null,0.011510533,2.42,0.014108634,2.34]
["8666_at","Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences","HRP1","YOL123w","YOL123W",null,null,0.011538945,2.37,0.013854879,2.32]
["10672_at","DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation, gene silencing, and DNA replication and repair","ABF1","YKL112w","YKL112W",null,null,0.009479234,2.28,0.010493306,2.3]
["4875_at","---","---","YGR130c","YGR130C",null,null,0.015305048,2.52,0.023536323,2.3]
["8465_at","Oleic acid-inducible, peroxisomal matrix localized lipase; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance; peroxisomal import is dependent on the PTS1 receptor, Pex5p and on self-interaction","LPX1","YOR084w","YOR084W",null,null,0.023352792,2.46,0.034516852,2.28]
["9702_at","Cytochrome b2 (L-lactate cytochrome-c oxidoreductase), component of the mitochondrial intermembrane space, required for lactate utilization; expression is repressed by glucose and anaerobic conditions","CYB2","YML054c","YML054C",null,null,0.031803627,2.38,0.041499376,2.27]
["10776_at","---","---","YKL187c","YKL187C",null,null,0.01302024,2.24,0.015286929,2.26]
["4258_at","Component of the holoenzyme form of RNA polymerase transcription factor TFIIH, has DNA-dependent ATPase/helicase activity and is required, with Rad3p, for unwinding promoter DNA; involved in DNA repair; homolog of human ERCC3","SSL2","YIL143c","YIL143C",null,null,0.027211513,2.16,0.028325824,2.25]
["7973_at","Alpha subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains beta-ketoacyl reductase and beta-ketoacyl synthase activities; phosphorylated","FAS2","YPL231w","YPL231W",null,null,0.00526164,2.18,0.006150739,2.25]
["10965_at","Protein with similarity to hect domain E3 ubiquitin-protein ligases, not essential for viability","HUL4","YJR036c","YJR036C",null,null,0.015253308,2.2,0.016521795,2.25]
["7853_at","Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA via its C-terminal ATPase activity, forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity","MOT1","YPL082c","YPL082C",null,null,0.011433553,2.21,0.011678218,2.25]
["4770_at","---","---","YGR250c","YGR250C",null,null,0.009234855,2.25,0.010593429,2.25]
["10445_s_at","Putative positive regulator of mannosylphosphate transferase (Mnn6p), involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases","MNN4","YKL201c","YKL201C",null,null,0.0234828,2.23,0.027594123,2.24]
["9066_at","---","---","YNL193w","YNL193W",null,null,0.011433553,2.3,0.01380821,2.24]
["8959_at","Malate synthase, enzyme of the glyoxylate cycle, involved in utilization of non-fermentable carbon sources; expression is subject to carbon catabolite repression; localizes in peroxisomes during growth in oleic acid medium","MLS1","YNL117w","YNL117W",null,null,0.011981552,2.38,0.01731492,2.24]
["6576_at","Protein of unknown function that associates with ribosomes; heterozygous deletion demonstrated increases in chromosome instability in a rad9 deletion background; protein abundance is decreased upon intracellular iron depletion","TMA17","YDL110c","YDL110C",null,null,0.021419922,2.39,0.03116587,2.24]
["6693_at","NAD(+)-dependent glutamate dehydrogenase, degrades glutamate to ammonia and alpha-ketoglutarate; expression sensitive to nitrogen catabolite repression and intracellular ammonia levels","GDH2","YDL215c","YDL215C",null,null,0.004176672,2.36,0.006256071,2.22]
["7357_at","Component of the small-subunit (SSU) processome, which is involved in the biogenesis of the 18S rRNA","UTP20","YBL004w","YBL004W",null,null,0.037467405,2.1,0.037016734,2.21]
["5183_at","D-serine dehydratase (aka D-serine ammonia-lyase); converts D-serine to pyruvate and ammonia by a reaction dependent on pyridoxal 5'-phosphate and zinc; may play a role in D-serine detoxification; L-serine is not a substrate","DSD1","YGL196w","YGL196W",null,null,0.028986571,2.43,0.044123042,2.21]
["6273_at","Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization","ADR1","YDR216w","YDR216W",null,null,0.005322267,2.52,0.010923131,2.2]
["6950_at","---","---","snR56","SNR56",{"$nulls":4},0.017487498,2.2]
["6937_at","Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources","GLK1","YCL040w","YCL040W",null,null,0.007521881,2.34,0.011678218,2.19]
["6204_at","Diacylglycerol pyrophosphate (DGPP) phosphatase, zinc-regulated vacuolar membrane-associated lipid phosphatase, dephosphorylates DGPP to phosphatidate (PA) and Pi, then PA to diacylglycerol; involved in lipid signaling and cell metabolism","DPP1","YDR284c","YDR284C",null,null,0.009481404,2.06,0.008334269,2.18]
["8475_at","---","---","YOR093c","YOR093C",null,null,0.011981552,2.3,0.01731492,2.18]
["10359_at","Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins, isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources","ISA1","YLL027w","YLL027W",null,null,0.038439143,2.16,0.043805312,2.16]
["7737_at","Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport","APL4","YPR029c","YPR029C",null,null,0.00526164,2.26,0.007691357,2.16]
["7869_at","Arginase, responsible for arginine degradation, expression responds to both induction by arginine and nitrogen catabolite repression; disruption enhances freeze tolerance","CAR1","YPL111w","YPL111W",0.029487757,2.27,0.011433553,1.92,0.00789221,2.15]
["8638_at","Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway involved in maintenance of cell wall integrity; involved in the response to heat shock and other stressors; regulates 1,3-beta-glucan synthesis","WSC3","YOL105c","YOL105C",null,null,0.016641496,2.19,0.021514155,2.15]
["7132_at","Peroxisomal AMP-binding protein, localizes to both the peroxisomal peripheral membrane and matrix, expression is highly inducible by oleic acid, similar to E. coli long chain acyl-CoA synthetase","PCS60","YBR222c","YBR222C",null,null,0.0234828,2.3,0.035288244,2.15]
["10472_at","Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p","PTR2","YKR093w","YKR093W",null,null,0.033391554,1.94,0.026785614,2.14]
["9665_at","Monomeric glyoxalase I, catalyzes the detoxification of methylglyoxal (a by-product of glycolysis) via condensation with glutathione to produce S-D-lactoylglutathione; expression regulated by methylglyoxal levels and osmotic stress","GLO1","YML004c","YML004C",null,null,0.016363202,2.42,0.02815286,2.14]
["4505_at","DNA helicase involved in rDNA replication and Ty1 transposition; relieves replication fork pauses at telomeric regions; structurally and functionally related to Pif1p","RRM3","YHR031c","YHR031C",null,null,0.005683301,2.2,0.008070919,2.12]
["8537_at","---","---","YOR019w","YOR019W",null,null,0.012723897,2.22,0.017793529,2.12]
["7755_at","---","---","YPR003c","YPR003C",null,null,0.01302024,2.2,0.017830977,2.11]
["11152_g_at","Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified gene YJL141C; null mutant displays increased levels of spontaneous Rad52p foci /// Serine-threonine protein kinase that is part of a glucose-sensing system involved in growth control in response to glucose availability; translocates from the cytoplasm to the nucleus and phosphorylates Pop2p in response to a glucose signal","IRC9 /// YAK1","YJL142c","YJL142C",null,null,0.023557536,1.98,0.023023967,2.1]
["8683_at","3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase); stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway","GRE2","YOL151w","YOL151W",null,null,0.011433553,2.25,0.016352536,2.1]
["9574_at","---","---","YMR087w","YMR087W",null,null,0.01224646,2.29,0.021202939,2.09]
["3948_s_at","Putative serine/threonine protein kinase that regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein","PTK1","YKL198c","YKL198C",null,null,0.013939684,2.57,0.031676237,2.09]
["9087_at","DNA-binding protein involved in either activation or repression of transcription, depending on binding site context; also binds telomere sequences and plays a role in telomeric position effect (silencing) and telomere structure","RAP1","YNL216w","YNL216W",null,null,0.011681399,2.02,0.011678218,2.08]
["5528_at","Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein","DMC1","YER179w","YER179W",null,null,0.03349533,2.13,0.04141803,2.08]
["11387_at","Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3; BDH2 is an essential gene","BDH2","YAL061w","YAL061W",null,null,0.038783662,2.15,0.049031932,2.08]
["5690_at","RNA-binding protein, activates mRNA decapping directly by binding to the mRNA substrate and enhancing the activity of the decapping proteins Dcp1p and Dcp2p; has a role in translation during heat stress","EDC2","YER035w","YER035W",null,null,0.037370823,1.9,0.031886894,2.06]
["9648_at","Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance","PPZ1","YML016c","YML016C",null,null,0.019722676,1.99,0.021975106,2.06]
["9758_at","Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway","RSC9","YML127w","YML127W",null,null,0.02241565,1.95,0.022979526,2.04]
["9998_at","Protein involved in early stages of meiotic recombination; required for chromosome synapsis; forms a complex with Rec104p and Spo11p necessary during the initiation of recombination","REC102","YLR329w","YLR329W",null,null,0.005476835,2.16,0.00856948,2.04]
["7907_at","Cell wall and vacuolar protein, required for wild-type resistance to vanadate","SVS1","YPL163c","YPL163C",null,null,0.01154612,2.19,0.01714258,2.04]
["8593_at","Arginosuccinate synthetase, catalyzes the formation of L-argininosuccinate from citrulline and L-aspartate in the arginine biosynthesis pathway; potential Cdc28p substrate","ARG1","YOL058w","YOL058W",null,null,0.031803627,1.7,0.017487498,2.03]
["10478_at","Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol","PCK1","YKR097w","YKR097W",null,null,0.03344852,2.12,0.04312308,2.03]
["4923_at","Minor isoform of pyruvate decarboxylase, decarboxylates pyruvate to acetaldehyde, involved in amino acid catabolism; transcription is glucose- and ethanol-dependent, and is strongly induced during sulfur limitation","PDC6","YGR087c","YGR087C",{"$nulls":4},0.03907704,2.02]
["6319_at","Inositol polyphosphate multikinase (IPMK), sequentially phosphorylates Ins(1,4,5)P3 to form Ins(1,3,4,5,6)P5; also has diphosphoinositol polyphosphate synthase activity; regulates arginine-, phosphate-, and nitrogen-responsive genes","ARG82","YDR173c","YDR173C",null,null,0.014341866,1.99,0.017184155,2]
["4763_at","Putative protein of unknown function; expression regulated by osmotic and alkaline stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","FMP43","YGR243w","YGR243W",null,null,0.016222555,2.02,0.020924348,2]
["7485_at","Protein involved in regulating the endocytosis of plasma membrane proteins; identified as a substrate for ubiquitination by Rsp5p and deubiquitination by Ubp2p; promoter contains several Gcn4p binding elements","ECM21","YBL101c","YBL101C",null,null,0.033468686,2.01,0.03937848,1.99]
["6212_at","Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; homolog of Sks1p","VHS1","YDR247w","YDR247W",null,null,0.003172797,2.48,0.008070919,1.99]
["5356_at","Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to Cmk2p and mammalian Cam Kinase II","CMK1","YFR014c","YFR014C",null,null,0.0182993,1.81,0.014404673,1.98]
["6099_at","Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi","GGA1","YDR358w","YDR358W",null,null,0.026142316,1.86,0.024410136,1.98]
["6898_at","Protein of unknown function; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization","LSB5","YCL034w","YCL034W",null,null,0.0234828,1.89,0.023536323,1.98]
["7828_at","Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress","ALD6","YPL061w","YPL061W",null,null,0.011786537,1.93,0.011694316,1.98]
["6441_at","Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; potentially phosphorylated by Cdc28p","VPS54","YDR027c","YDR027C",null,null,0.020927202,1.98,0.024722164,1.98]
["8437_at","Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation","CRC1","YOR100c","YOR100C",null,null,0.018709198,2.28,0.03636863,1.98]
["5219_at","Clathrin heavy chain, subunit of the major coat protein involved in intracellular protein transport and endocytosis; two heavy chains form the clathrin triskelion structural component; the light chain (CLC1) is thought to regulate function","CHC1","YGL206c","YGL206C",null,null,0.027884513,1.97,0.032862578,1.96]
["7270_i_at","---","---","YBR090c","YBR090C",null,null,0.018646829,2.07,0.027070807,1.96]
["7974_at","Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in growth on non-fermentable carbon sources, response to salt stress and cell wall biosynthesis","USV1","YPL230w","YPL230W",null,null,0.021419922,2.11,0.032862578,1.96]
["4736_at","High affinity nicotinic acid plasma membrane permease, responsible for uptake of low levels of nicotinic acid; expression of the gene increases in the absence of extracellular nicotinic acid or para-aminobenzoate (PABA)","TNA1","YGR260w","YGR260W",null,null,0.02506155,1.85,0.024461657,1.95]
["10781_at","Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities","FAS1","YKL182w","YKL182W",null,null,0.009228777,1.97,0.010989325,1.95]
["8678_at","Subunit of a palmitoyltransferase, composed of Shr5p and Erf2p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; palmitoylation is required for Ras2p membrane localization","SHR5","YOL110w","YOL110W",null,null,0.013395333,2.14,0.023023967,1.95]
["9608_at","---","---","YMR031c","YMR031C",null,null,0.03562021,1.83,0.031676237,1.94]
["8467_at","Lipid-binding protein containing three calcium and lipid binding domains; non-tagged protein localizes to mitochondria and GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact","TCB1","YOR086c","YOR086C",null,null,0.012312659,1.84,0.011694316,1.94]
["7207_at","Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Sur1p","CSH1","YBR161w","YBR161W",null,null,0.011065401,1.96,0.011696725,1.94]
["10935_at","---","---","YJR096w","YJR096W",null,null,0.011681399,2.02,0.015485019,1.94]
["3263_i_at","---","---","Unknown","YGLWDELTA6",null,null,0.02153654,2.18,0.038846977,1.94]
["9739_at","Subunit of the nuclear pore complex (NPC), involved in the structural organization of the complex and of the nuclear envelope, also involved in nuclear envelope permeability, interacts with Pom152p and Nic96p","NUP188","YML103c","YML103C",{"$nulls":4},0.049340285,1.94]
["4768_at","6-phosphogluconolactonase with similarity to Sol3p","SOL4","YGR248w","YGR248W",null,null,0.035583306,2.02,0.047561858,1.93]
["11023_at","Vacuolar transporter, imports large neutral amino acids into the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters","AVT1","YJR001w","YJR001W",null,null,0.025727842,1.86,0.027297346,1.92]
["8375_at","Non-essential, stress induced regulatory protein containing a HIT (histidine triad) motif; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway, similar to Dcs1p.","DCS2","YOR173w","YOR173W",null,null,0.01777198,2.01,0.024318546,1.92]
["10029_at","Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM","CDC3","YLR314c","YLR314C",null,null,0.026403429,1.74,0.021706928,1.91]
["7057_at","---","---","YBR284w","YBR284W",null,null,0.03956282,1.92,0.04625217,1.91]
["6646_at","D-lactate dehydrogenase, oxidizes D-lactate to pyruvate, transcription is heme-dependent, repressed by glucose, and derepressed in ethanol or lactate; located in the mitochondrial inner membrane","DLD1","YDL174c","YDL174C",null,null,0.017260492,2,0.023536323,1.91]
["10617_at","UDP-glucose pyrophosphorylase (UGPase), catalyses the reversible formation of UDP-Glc from glucose 1-phosphate and UTP, involved in a wide variety of metabolic pathways, expression modulated by Pho85p through Pho4p","UGP1","YKL035w","YKL035W",null,null,0.034512978,1.82,0.032862578,1.9]
["5715_at","Long chain fatty acyl-CoA synthetase; accepts a wider range of acyl chain lengths than Faa1p, preferring C9:0-C13:0; involved in the activation of endogenous pools of fatty acids","FAA2","YER015w","YER015W",null,null,0.03562021,1.91,0.04103486,1.9]
["5116_at","Protein required for inositol prototrophy, identified as an ortholog of the FIT family of proteins involved in triglyceride droplet biosynthesis; disputed role in the synthesis of inositol phospholipids from inositol","SCS3","YGL126w","YGL126W",null,null,0.018537056,1.92,0.023023967,1.9]
["9615_at","Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression","MSN2","YMR037c","YMR037C",null,null,0.011522481,1.94,0.013854879,1.9]
["4970_at","Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-a2 regulator; mediates cell type control of sporulation","RME1","YGR044c","YGR044C",null,null,0.0234828,2.05,0.03782841,1.9]
["5718_at","Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering","SPC25","YER018c","YER018C",null,null,0.026529536,1.85,0.028403016,1.89]
["11016_at","Adenylate cyclase, required for cAMP production and cAMP-dependent protein kinase signaling; the cAMP pathway controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation","CYR1","YJL005w","YJL005W",null,null,0.023993563,1.86,0.026957251,1.89]
["6120_at","Swi2/Snf2-related ATPase that is the structural component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A","SWR1","YDR334w","YDR334W",null,null,0.03529426,1.93,0.042446047,1.89]
["6221_at","Catalase A, breaks down hydrogen peroxide in the peroxisomal matrix formed by acyl-CoA oxidase (Pox1p) during fatty acid beta-oxidation","CTA1","YDR256c","YDR256C",null,null,0.024292478,1.98,0.03430663,1.89]
["7324_at","---","---","YBR056w","YBR056W",null,null,0.019323736,2.09,0.033943694,1.89]
["7781_at","Microtubule associated protein; regulates microtubule dynamics; required for accurate meiotic chromosome segregation; null mutant displays large budded cells due to delayed mitotic progression, increased levels of spontaneous Rad52 foci","IRC15","YPL017c","YPL017C",null,null,0.012773143,2.23,0.028317872,1.88]
["8430_at","Protein involved in regulation of Rsp5p, which is an essential HECT ubiquitin ligase; has a WW domain consensus motif of PPPSY (residues 131-135) that mediates binding of Rsp5p to Ubp2p; contains an UBA domain","RUP1","YOR138c","YOR138C",null,null,0.014492173,1.86,0.01731492,1.87]
["10482_at","Protein involved in repression of transcription at the silent mating-type loci HML and HMR; recruitment to silent chromatin requires interactions with Orc1p and with Sir4p, through a common Sir1p domain; binds to centromeric chromatin","SIR1","YKR101w","YKR101W",null,null,0.040212266,1.78,0.038846977,1.86]
["10446_s_at","Putative serine/threonine protein kinase that regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein","PTK1","YKL198C","YKL199C",null,null,0.018709198,1.79,0.019827144,1.86]
["7195_at","NADP+ dependent arabinose dehydrogenase, involved in carbohydrate metabolism; purified as homodimer; naturally occurs with a N-terminus degradation product","ARA1","YBR149w","YBR149W",null,null,0.018114772,1.94,0.025053909,1.85]
["6642_at","D-lactate dehydrogenase, located in the mitochondrial matrix","DLD2","YDL178w","YDL178W",{"$nulls":4},0.046048332,1.84]
["4521_at","Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology and sporulation; homolog of the human protein Dullard","NEM1","YHR004c","YHR004C",null,null,0.03562021,1.72,0.031211212,1.83]
["7135_at","---","---","YBR225w","YBR225W",null,null,0.023058843,1.74,0.021975106,1.83]
["10597_at","Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins","UFD4","YKL010c","YKL010C",null,null,0.029508695,1.69,0.02477741,1.82]
["6865_at","Protein of unknown function that may regulate assembly and disassembly of the septin ring; colocalizes and interacts with septin subunits; potential role in actin cytoskeletal organization","SYP1","YCR030c","YCR030C",null,null,0.046938244,1.74,0.044068515,1.82]
["11153_at","Serine-threonine protein kinase that is part of a glucose-sensing system involved in growth control in response to glucose availability; translocates from the cytoplasm to the nucleus and phosphorylates Pop2p in response to a glucose signal","YAK1","YJL141c","YJL141C",null,null,0.0164224,1.8,0.018599361,1.82]
["9321_at","Triacylglycerol lipase of the lipid particle, responsible for all the TAG lipase activity of the lipid particle; contains the consensus sequence motif GXSXG, which is found in lipolytic enzymes; required with Tgl4p for timely bud formation","TGL3","YMR313c","YMR313C",null,null,0.018733501,1.75,0.02076058,1.81]
["8171_at","Transcriptional activator essential for nuclear division; localized to the nucleus; essential component of the mechanism that activates the expression of a set of late-S-phase-specific genes","NDD1","YOR372c","YOR372C",null,null,0.017689388,1.77,0.018876411,1.81]
["6488_at","Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability","OSH2","YDL019c","YDL019C",null,null,0.029802034,1.82,0.036039323,1.81]
["6485_at","NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p","GPD1","YDL022w","YDL022W",null,null,0.011981552,1.84,0.015457659,1.81]
["4887_at","Vacuolar protein sorting (VPS) protein required for cytoplasm to vacuole targeting of proteins","VPS62","YGR141w","YGR141W",null,null,0.020914815,1.91,0.03144248,1.81]
["7909_at","Protein involved in establishment of cell polarity and bud emergence; interacts with the Rho1p small GTP-binding protein and with the Rho-type GTPase Cdc42p; involved in maintenance of proper telomere length","BEM4","YPL161c","YPL161C",null,null,0.02158994,1.91,0.03226712,1.81]
["10027_at","---","---","YLR312c","YLR312C",null,null,0.016103525,1.96,0.025765894,1.81]
["9668_at","Carnitine acetyl-CoA transferase present in both mitochondria and peroxisomes, transfers activated acetyl groups to carnitine to form acetylcarnitine which can be shuttled across membranes","CAT2","YML042w","YML042W",null,null,0.013395333,2,0.023738401,1.81]
["5534_at","Plasma membrane protein with roles in the uptake of protoprophyrin IX and the efflux of heme; expression is induced under both low-heme and low-oxygen conditions; member of the fungal lipid-translocating exporter (LTE) family of proteins","PUG1","YER185w","YER185W",{"$nulls":4},0.03250793,1.81]
["10075_at","Non-essential hydrolase involved in mRNA decapping, may function in a feedback mechanism to regulate deadenylation, contains pyrophosphatase activity and a HIT (histidine triad) motif; interacts with neutral trehalase Nth1p","DCS1","YLR270w","YLR270W",null,null,0.018114772,1.88,0.02477741,1.8]
["4844_at","Thiazole synthase, catalyzes formation of a thiazole intermediate during thiamine biosynthesis; required for mitochondrial genome stability in response to DNA damaging agents","THI4","YGR144w","YGR144W",null,null,0.025008066,1.92,0.0390088,1.8]
["4843_at","Protein involved in sphingolipid biosynthesis; type II membrane protein with similarity to Kre6p","SKN1","YGR143w","YGR143W",null,null,0.024292478,2,0.043378543,1.8]
["5777_at","Essential N-acetylglucosamine-phosphate mutase; converts GlcNAc-6-P to GlcNAc-1-P, which is a precursor for the biosynthesis of chitin and for the formation of N-glycosylated mannoproteins and glycosylphosphatidylinositol anchors","PCM1","YEL058w","YEL058W",null,null,0.0234828,1.7,0.022513641,1.79]
["4205_at","Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; phosphorylated by the TORC2 complex","SLM1","YIL105c","YIL105C",null,null,0.02153654,1.7,0.021514155,1.79]
["7844_at","Cytosolic and mitochondrial glutathione oxidoreductase, converts oxidized glutathione to reduced glutathione; mitochondrial but not cytosolic form has a role in resistance to hyperoxia","GLR1","YPL091w","YPL091W",null,null,0.0164224,1.81,0.021514155,1.79]
["6179_at","Dinucleoside triphosphate hydrolase; has similarity to the tumor suppressor FHIT and belongs to the histidine triad (HIT) superfamily of nucleotide-binding proteins","HNT2","YDR305c","YDR305C",null,null,0.036427666,1.87,0.048864435,1.79]
["9547_at","Phosphoglucomutase, catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase","PGM2","YMR105c","YMR105C",null,null,0.036086515,1.87,0.04954544,1.79]
["4369_at","Tripartite DNA replication factor with single-stranded DNA-dependent ATPase, ATP-dependent nuclease, and helicase activities; required for Okazaki fragment processing; involved in DNA repair; cell-cycle dependent localization","DNA2","YHR164c","YHR164C",null,null,0.02447415,1.74,0.026673885,1.78]
["10602_at","---","---","YKL050c","YKL050C",null,null,0.04654783,1.75,0.04866978,1.78]
["6565_at","Peroxisomal malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the glyoxylate cycle","MDH3","YDL078c","YDL078C",null,null,0.013395333,1.92,0.022969274,1.78]
["9386_at","Long chain fatty acyl-CoA synthetase, regulates protein modification during growth in the presence of ethanol, functions to incorporate palmitic acid into phospholipids and neutral lipids","FAA4","YMR246w","YMR246W",{"$nulls":4},0.040738534,1.78]
["6193_at","Meiosis-specific component of the spindle pole body, part of the leading edge protein (LEP) coat, forms a ring-like structure at the leading edge of the prospore membrane during meiosis II","DON1","YDR273w","YDR273W",null,null,0.024518149,1.64,0.021975106,1.76]
["9725_at","Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p","FPR3","YML074c","YML074C",null,null,0.03489877,1.67,0.031304922,1.76]
["7227_at","Genome integrity checkpoint protein and PI kinase superfamily member; signal transducer required for cell cycle arrest and transcriptional responses prompted by damaged or unreplicated DNA; monitors and participates in meiotic recombination","MEC1","YBR136w","YBR136W",null,null,0.034512978,1.71,0.03359515,1.76]
["9096_at","Protein involved in mRNA export, component of the transcription export (TREX) complex","TEX1","YNL253w","YNL253W",null,null,0.018114772,1.79,0.023023967,1.76]
["7582_at","Glycogen debranching enzyme containing glucanotranferase and alpha-1,6-amyloglucosidase activities, required for glycogen degradation; phosphorylated in mitochondria","GDB1","YPR184w","YPR184W",null,null,0.01777198,1.8,0.023023967,1.76]
["9612_at","---","---","YMR034c","YMR034C",null,null,0.039004453,1.65,0.033992182,1.75]
["8389_at","Alpha subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate; phosphorylated","LSC1","YOR142w","YOR142W",null,null,0.023557536,1.75,0.027840253,1.75]
["4107_at","Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); localized to the nucleus and the cytoplasm","VID28","YIL017c","YIL017C",null,null,0.020021401,1.62,0.01731492,1.74]
["4230_at","ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic genes; essential helicase-related protein homologous to Snf2p","STH1","YIL126w","YIL126W",null,null,0.03034784,1.7,0.03226712,1.74]
["6151_at","Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles","SWA2","YDR320c","YDR320C",null,null,0.023661098,1.75,0.02866018,1.74]
["5174_at","Protein that interacts with Rab GTPases, localized to late Golgi vesicles; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport","YIP5","YGL161c","YGL161C",null,null,0.018709198,1.75,0.023536323,1.74]
["6372_at","Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase","DNF2","YDR093w","YDR093W",null,null,0.015900321,1.78,0.021230683,1.74]
["8616_at","Receptor protein specific for the cytoplasm-to-vacuole targeting (Cvt) pathway; delivers cargo proteins aminopeptidase I (Lap4p) and alpha-mannosidase (Ams1p) to the phagophore assembly site for packaging into Cvt vesicles","ATG19","YOL082w","YOL082W",null,null,0.026403429,1.78,0.033992182,1.74]
["4510_at","Essential nuclear envelope integral membrane protein identified as a suppressor of a conditional mutation in the major karyopherin, CRM1; homologous to and interacts with Brr6p, a nuclear envelope protein involved in nuclear export","BRL1","YHR036w","YHR036W",null,null,0.012125096,1.88,0.021230683,1.74]
["5561_at","ATP (CTP):tRNA-specific tRNA nucleotidyltransferase; different forms targeted to the nucleus, cytosol, and mitochondrion are generated via the use of multiple transcriptional and translational start sites","CCA1","YER168c","YER168C",{"$nulls":4},0.042495396,1.74]
["5382_at","Proteasome activator subunit; found in association with core particles, with and without the 19S regulatory particle; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200","BLM10","YFL006w","YFL006W",null,null,0.044252113,1.66,0.04081008,1.73]
["4162_at","---","---","YIL055c","YIL055C",null,null,0.019323736,1.71,0.022278732,1.73]
["8696_at","Protein of unknown function; may interact with ribosomes, based on co-purification experiments; null mutation suppresses cdc13-1 temperature sensitivity","RTC1","YOL138c","YOL138C",null,null,0.02506155,1.79,0.03468507,1.73]
["8003_at","---","---","YPL247c","YPL247C",null,null,0.027613288,1.82,0.04053415,1.73]
["8220_at","Catalytic subunit of the mitochondrial DNA polymerase; conserved C-terminal segment is required for the maintenance of mitochondrial genome; related to human POLG, which has been associated with mitochondrial diseases","MIP1","YOR330c","YOR330C",null,null,0.006332554,2.01,0.016174687,1.73]
["9201_at","AAA-peroxin that heterodimerizes with AAA-peroxin Pex1p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol","PEX6","YNL329c","YNL329C",null,null,0.034040857,1.67,0.033361476,1.72]
["10795_at","Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose","JEN1","YKL217w","YKL217W",null,null,0.041279823,1.71,0.045333907,1.72]
["8033_at","Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial distribution determined by the N-terminal targeting sequence, protein conformation, and status of glyoxylate shunt; phosphorylated in mitochondria","FUM1","YPL262w","YPL262W",null,null,0.028570345,1.72,0.03359515,1.72]
["8506_at","5'-3' exonuclease and flap-endonuclease involved in recombination, double-strand break repair and DNA mismatch repair; member of the Rad2p nuclease family, with conserved N and I nuclease domains","EXO1","YOR033c","YOR033C",null,null,0.013395333,1.76,0.018342346,1.72]
["9638_at","Nuclear protein that plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; negatively regulates pseudohyphal differentiation; homologous to several transcription factors","SOK2","YMR016c","YMR016C",null,null,0.019500295,1.79,0.02866018,1.72]
["6430_at","---","---","YDR061w","YDR061W",null,null,0.019412441,1.61,0.01736623,1.71]
["5184_at","Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate Gcn2p activation by an uncharged tRNA","GCN1","YGL195w","YGL195W",null,null,0.022789545,1.7,0.026058923,1.71]
["5240_at","Protein required for function of the Sit4p protein phosphatase, member of a family of similar proteins that form complexes with Sit4p, including Sap155p, Sap185p, and Sap190p","SAP4","YGL229c","YGL229C",null,null,0.01777198,1.78,0.024643283,1.71]
["7749_at","Primary component of eisosomes, which are large immobile patch structures at the cell cortex associated with endocytosis, along with Pil1p and Sur7p; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways","LSP1","YPL004c","YPL004C",null,null,0.025008066,1.78,0.036039323,1.71]
["8378_at","Ferrochelatase, a mitochondrial inner membrane protein, catalyzes the insertion of ferrous iron into protoporphyrin IX, the eighth and final step in the heme biosynthetic pathway","HEM15","YOR176w","YOR176W",null,null,0.027132705,1.87,0.045873955,1.71]
["4360_at","Mitochondrial protein with a potential role in promoting mitochondrial fragmentation during programmed cell death in response to high levels of alpha-factor mating pheromone or the drug amiodarone","YSP1","YHR155w","YHR155W",{"$nulls":4},0.038846977,1.71]
["7598_at","Protein involved in regulation of mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p) of the Fo-F1 ATP synthase; functions with Nca3p","NCA2","YPR155c","YPR155C",{"$nulls":4},0.032054007,1.71]
["7292_at","Amino acid transport protein for valine, leucine, isoleucine, and tyrosine, low-affinity tryptophan and histidine transporter; overexpression confers FK506 and FTY720 resistance","TAT1","YBR069c","YBR069C",null,null,0.032563023,1.66,0.03287144,1.7]
["9111_at","Probable type-III integral membrane protein of unknown function, has regions of similarity to mitochondrial electron transport proteins","YTP1","YNL237w","YNL237W",null,null,0.040776793,1.67,0.042446047,1.7]
["7317_at","RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription","REB1","YBR049c","YBR049C",null,null,0.019722676,1.7,0.024040537,1.7]
["4135_at","Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, activates transcription of genes involved in utilization of non-optimal carbon sources; involved in telomere maintenance","CST6","YIL036w","YIL036W",null,null,0.023801474,1.71,0.029466106,1.7]
["10448_s_at","---","---","YKL033w-a","YKL033W-A",null,null,0.021240884,1.78,0.031344973,1.7]
["8654_at","Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression","HAL9","YOL089c","YOL089C",null,null,0.022789545,1.84,0.037931275,1.7]
["7782_at","Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; can form the prion [SWI+]","SWI1","YPL016w","YPL016W",null,null,0.026403429,1.86,0.045333907,1.7]
["7217_at","Synthase subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway","TPS1","YBR126c","YBR126C",null,null,0.0234828,1.87,0.041897196,1.7]
["6377_at","Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p","MSH6","YDR097c","YDR097C",{"$nulls":4},0.03368312,1.7]
["5218_at","Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure","SPT16","YGL207w","YGL207W",null,null,0.027501626,1.64,0.028099533,1.69]
["10888_at","Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; involved in position-dependent gene silencing and nucleosome reassembly","HIR3","YJR140c","YJR140C",null,null,0.023557536,1.65,0.025053909,1.69]
["8656_at","---","---","YOL087c","YOL087C",null,null,0.030875266,1.68,0.03430663,1.69]
["5735_at","Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern","GLC3","YEL011w","YEL011W",null,null,0.029339138,1.69,0.033992182,1.69]
["9727_at","Lipid-binding protein, localized to the bud via specific mRNA transport; non-tagged protein detected in a phosphorylated state in mitochondria; GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact","TCB3","YML072c","YML072C",null,null,0.03984505,1.73,0.04990368,1.69]
["9913_at","---","---","YLR422w","YLR422W",null,null,0.023076773,1.78,0.033992182,1.69]
["10123_at","Kynureninase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p","BNA5","YLR231c","YLR231C",null,null,0.019722676,1.81,0.032991562,1.69]
["6798_f_at","Putative protein of unknown function /// Putative protein of unknown function /// Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme","PAU21 /// PAU22 /// PAU3","YCR104w","YCR104W",null,null,0.020914815,1.89,0.04053415,1.69]
["10357_at","Protein involved in negative regulation of transcription of iron regulon; forms an iron independent complex with Fra2p, Grx3p, and Grx4p; cytosolic; mutant fails to repress transcription of iron regulon and is defective in spore formation","FRA1","YLL029w","YLL029W",null,null,0.027884513,1.57,0.02320247,1.68]
["4455_at","Glutamine-dependent NAD(+) synthetase, essential for the formation of NAD(+) from nicotinic acid adenine dinucleotide","QNS1","YHR074w","YHR074W",null,null,0.036086515,1.66,0.038846977,1.68]
["4227_at","Component of the RAM signaling network that is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with protein kinase Cbk1p and also with Kic1p","TAO3","YIL129c","YIL129C",null,null,0.0279215,1.73,0.038771104,1.68]
["7415_at","Alpha-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport","APL3","YBL037w","YBL037W",null,null,0.011786537,1.79,0.019334326,1.68]
["10026_at","---","---","YLR311c","YLR311C",null,null,0.036157615,1.57,0.029887872,1.67]
["5361_at","1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis","FAB1","YFR019w","YFR019W",null,null,0.030033931,1.68,0.03636863,1.67]
["9938_at","Transcription factor that controls expression of ribosome biogenesis genes in response to nutrients and stress, regulates G2/M transitions during mitotic cell cycle and DNA-damage response, modulates cell size; regulated by TORC1 and Mrs6p","SFP1","YLR403w","YLR403W",null,null,0.021085508,1.71,0.02831074,1.67]
["7268_at","High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Ap; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to certain promoters","NHP6B","YBR089C-A","YBR090C-A",null,null,0.026403429,1.8,0.043051194,1.67]
["7731_at","Catalytic subunit of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover","YME1","YPR024w","YPR024W",null,null,0.013256554,1.89,0.027566569,1.67]
["8294_at","Polyamine transport protein, recognizes spermine, putrescine, and spermidine; localizes to the plasma membrane; member of the major facilitator superfamily","TPO4","YOR273c","YOR273C",{"$nulls":4},0.04224675,1.67]
["5025_at","Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span","PNC1","YGL037c","YGL037C",null,null,0.034040857,1.63,0.03574261,1.66]
["7462_at","Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; mutation is functionally complemented by the bacterial GatB ortholog","PET112","YBL080c","YBL080C",null,null,0.021008803,1.76,0.03294668,1.66]
["9290_f_at","Putative protein of unknown function /// Putative protein of unknown function /// Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme","PAU21 /// PAU22 /// PAU3","YMR325w","YMR325W",null,null,0.01224646,1.91,0.027566569,1.66]
["6110_at","NADPH-dependent aldo-keto reductase, reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases","YPR1","YDR368w","YDR368W",{"$nulls":4},0.047575828,1.66]
["6086_at","GTPase activating protein (GAP) for Rho1p, involved in signaling to the actin cytoskeleton, null mutations suppress tor2 mutations and temperature sensitive mutations in actin; potential Cdc28p substrate","SAC7","YDR389w","YDR389W",{"$nulls":4},0.04990368,1.66]
["5622_at","Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; involved in sphingolipid metabolism; contains a RasGEFN domain","TSC11","YER093c","YER093C",null,null,0.03896845,1.53,0.029082483,1.65]
["4129_at","Mitochondrial protein kinase involved in negative regulation of pyruvate dehydrogenase complex activity by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp2p and phosphatases Ptc5p and Ptc6p","PKP1","YIL042c","YIL042C",null,null,0.022789545,1.63,0.025053909,1.65]
["8836_at","Para-aminobenzoate (PABA) synthase, has similarity to Escherichia coli PABA synthase components PabA and PabB","ABZ1","YNR033w","YNR033W",null,null,0.03604758,1.66,0.041911382,1.65]
["3439_f_at","---","---","tQ(UUG)D2","TQ(UUG)D2",null,null,0.019466328,1.79,0.034823235,1.65]
["6338_at","Ethanolamine kinase, primarily responsible for phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway; exhibits some choline kinase activity, thus contributing to phosphatidylcholine synthesis via the CDP-choline pathway","EKI1","YDR147w","YDR147W",{"$nulls":4},0.03579061,1.65]
["9952_at","GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically lethal with mutations in rom1, which also encodes a GEP","ROM2","YLR371w","YLR371W",{"$nulls":4},0.04634639,1.65]
["4757_at","---","---","YGR237c","YGR237C",null,null,0.0234828,1.62,0.026027128,1.64]
["4839_at","Ubiquitin-protein ligase (E3) that interacts with Rad6p/Ubc2p to ubiquitinate substrates of the N-end rule pathway; binds to the Rpn2p, Rpt1p, and Rpt6p proteins of the 19S particle of the 26S proteasome","UBR1","YGR184c","YGR184C",null,null,0.022204166,1.63,0.025206529,1.64]
["5678_at","Delta 1-pyrroline-5-carboxylate reductase, catalyzes the last step in proline biosynthesis","PRO3","YER023w","YER023W",null,null,0.032723133,1.66,0.039919835,1.64]
["6058_at","One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic","TRS120","YDR407c","YDR407C",null,null,0.018709198,1.72,0.027925674,1.64]
["9433_at","---","---","YMR206w","YMR206W",null,null,0.02506155,1.73,0.038846977,1.64]
["9707_at","Protein involved in pre-mRNA splicing; component of the pre-spliceosome; associates with U2 snRNA; involved in ER to Golgi transport","RSE1","YML049c","YML049C",null,null,0.01442804,1.75,0.02327902,1.64]
["8564_at","Putative precursor to the subtilisin-like protease III","YSP3","YOR003w","YOR003W",null,null,0.011786537,1.78,0.021230683,1.64]
["4069_at","ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting","MGA2","YIR033w","YIR033W",null,null,0.013853301,1.81,0.02635819,1.64]
["10158_at","Protein that interacts with and inhibits carboxypeptidase Y and Ira2p; phosphatidylethanolamine-binding protein (PEBP) family member; targets to vacuolar membranes during stationary phase; acetylated by NatB N-terminal acetyltransferase","TFS1","YLR178c","YLR178C",null,null,0.018537056,1.9,0.042446047,1.64]
["6652_at","Bifunctional enzyme containing both alcohol dehydrogenase and glutathione-dependent formaldehyde dehydrogenase activities, functions in formaldehyde detoxification and formation of long chain and complex alcohols, regulated by Hog1p-Sko1p","SFA1","YDL168w","YDL168W",null,null,0.048727226,1.52,0.037931275,1.63]
["9439_at","Specificity factor required for Rsp5p-dependent ubiquitination and sorting of specific cargo proteins at the multivesicular body; mRNA is targeted to the bud via the mRNA transport system involving She2p","EAR1","YMR171c","YMR171C",null,null,0.023661098,1.62,0.026957251,1.63]
["5717_at","Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes","AFG3","YER017c","YER017C",null,null,0.018709198,1.67,0.025053909,1.63]
["9442_s_at","DNA damage-responsive protein, expression is increased in response to heat-shock stress or treatments that produce DNA lesions; contains multiple repeats of the amino acid sequence NNNDSYGS","DDR48","YMR173w","YMR173W",null,null,0.0145058,1.72,0.023499496,1.63]
["11388_at","NAD-dependent (R,R)-butanediol dehydrogenase, catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source","BDH1","YAL060w","YAL060W",null,null,0.02185912,1.73,0.036039323,1.63]
["5759_at","P-type ATPase, ion transporter of the ER membrane involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1","SPF1","YEL031w","YEL031W",{"$nulls":4},0.04081008,1.63]
["8624_at","---","---","YOL073c","YOL073C",{"$nulls":4},0.043805312,1.63]
["9759_at","3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase, catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA; involved in the second step in mevalonate biosynthesis","ERG13","YML126c","YML126C",null,null,0.028986571,1.54,0.025108399,1.62]
["5011_at","Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a","PMC1","YGL006w","YGL006W",null,null,0.031579945,1.59,0.03226712,1.62]
["10694_at","Mitochondrial intermediate peptidase, cleaves N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis","2001-10-01","YKL134c","YKL134C",null,null,0.018709198,1.63,0.023023967,1.62]
["10025_at","Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP; required for progression through G1","CDC25","YLR310c","YLR310C",null,null,0.019323736,1.67,0.027477127,1.62]
["7591_at","---","---","YPR148c","YPR148C",null,null,0.048727226,1.5,0.03718559,1.61]
["7219_at","Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I (with Vps34/15/30p); Atg14p targets complex I to the phagophore assembly site (PAS); required for localizing additional ATG proteins to the PAS; homolog of human Barkor","ATG14","YBR128c","YBR128C",null,null,0.036514025,1.58,0.038048793,1.61]
["8407_at","Nuclear import receptor, mediates the nuclear localization of proteins involved in mRNA-nucleus export; promotes dissociation of mRNAs from the nucleus-cytoplasm mRNA shuttling protein Npl3p","MTR10","YOR160w","YOR160W",null,null,0.026351199,1.6,0.030458031,1.61]
["8264_at","Member of the protein disulfide isomerase (PDI) family; interacts with and inhibits the chaperone activity of Cne1p; MPD1 overexpression in a pdi1 null mutant suppresses defects in Pdi1p functions such as carboxypeptidase Y maturation","MPD1","YOR288c","YOR288C",null,null,0.027862769,1.62,0.033125088,1.61]
["7278_at","Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p","VPS15","YBR097w","YBR097W",null,null,0.03295831,1.69,0.04767422,1.61]
["4441_at","Protein involved in the transport of cell wall components from the Golgi to the cell surface; similar in structure and functionally redundant with Sbe2p; involved in bud growth","SBE22","YHR103w","YHR103W",null,null,0.017965833,1.72,0.028317872,1.61]
["4442_at","Aldose reductase involved in methylglyoxal, d-xylose, arabinose, and galactose metabolism; stress induced (osmotic, ionic, oxidative, heat shock, starvation and heavy metals); regulated by the HOG pathway","GRE3","YHR104w","YHR104W",null,null,0.018709198,1.74,0.03250793,1.61]
["8837_at","Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol2p, Sol3p, and Sol4p","SOL1","YNR034w","YNR034W",null,null,0.026489092,1.76,0.047575828,1.61]
["7269_g_at","High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Ap; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to certain promoters","NHP6B","YBR089C-A","YBR090C-A",null,null,0.018709198,1.86,0.042501356,1.61]
["8536_at","Membrane protein that binds the ubiquitin ligase Rsp5p via its 2 PY motifs; overexpression confers resistance to the GST substrate o-dinitrobenzene,zinc, and calcium; proposed to regulate the endocytosis of plasma membrane proteins","ROD1","YOR018w","YOR018W",{"$nulls":4},0.046251643,1.61]
["10702_at","Serine/threonine protein kinase required for receptor-mediated endocytosis; involved in sphingolipid-mediated and cell integrity signaling pathways; localized to the bud neck, cytosol and plasma membrane; homolog of mammalian kinase SGK","YPK1","YKL126w","YKL126W",null,null,0.042891197,1.53,0.037931275,1.6]
["10468_at","Triacylglycerol lipase involved in triacylglycerol mobilization and degradation; found in lipid particles; phosphorylated and activated by Cdc28p; required with Tgl3p for timely bud formation","TGL4","YKR089c","YKR089C",null,null,0.037118897,1.55,0.03636863,1.6]
["8692_at","Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain both S1 and KH RNA binding domains; has similarity to human hRrp40p (EXOSC3)","RRP40","YOL142w","YOL142W",null,null,0.03931688,1.59,0.042495396,1.6]
["5991_at","AMP-activated serine/threonine protein kinase found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis","SNF1","YDR477w","YDR477W",null,null,0.026400665,1.62,0.032862578,1.6]
["4903_at","Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; Ipl1p target for regulating kinetochore-MT attachments","DAM1","YGR113w","YGR113W",null,null,0.016103525,1.7,0.025053909,1.6]
["7216_at","Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppressor of the synthetic lethality of a cnb1 mpk1 double deletion; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity","PTC4","YBR125c","YBR125C",null,null,0.018511113,1.74,0.032862578,1.6]
["9662_at","Basic leucine zipper (bZIP) transcription factor required for oxidative stress tolerance; activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus; mediates resistance to cadmium","YAP1","YML007w","YML007W",null,null,0.039788272,1.48,0.029909361,1.59]
["6282_at","Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX; evolutionarily-conserved adherin","SCC2","YDR180w","YDR180W",null,null,0.040969003,1.56,0.042120606,1.59]
["10157_at","---","---","YLR177w","YLR177W",null,null,0.028161952,1.57,0.030458031,1.59]
["9012_at","Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins","NSG2","YNL156c","YNL156C",null,null,0.03562021,1.64,0.04658004,1.59]
["3364_f_at","---","---","tQ(UUG)E2","TQ(UUG)E2",null,null,0.025417518,1.65,0.037576444,1.59]
["4448_at","Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis, required for respiratory growth and for normal mitochondrial morphology","HTD2","YHR067w","YHR067W",null,null,0.019920366,1.66,0.03157696,1.59]
["8933_at","Integral vacuolar membrane protein involved in vacuole inheritance and morphology; activates Fab1p kinase activity under basal conditions and also after hyperosmotic shock","VAC7","YNL054w","YNL054W",{"$nulls":4},0.045564905,1.59]
["6137_at","Protein involved in the transport of cell wall components from the Golgi to the cell surface; required for bud growth","SBE2","YDR351w","YDR351W",null,null,0.04700195,1.49,0.038787942,1.58]
["11068_at","---","---","YJL045w","YJL045W",null,null,0.033174235,1.65,0.04647901,1.58]
["9163_at","Low affinity vacuolar membrane localized monovalent cation/H+ antiporter; member of the calcium exchanger (CAX) family; potential Cdc28p substrate","VNX1","YNL321w","YNL321W",null,null,0.021059485,1.73,0.040557846,1.58]
["4203_at","---","---","YIL108w","YIL108W",{"$nulls":4},0.04081008,1.58]
["4097_at","---","---","YIR016w","YIR016W",{"$nulls":4},0.045333907,1.58]
["7090_at","Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); involved in DNA mismatch repair during slow growth; weak similarity to Msh1p; related to human 19S subunit S5b","HSM3","YBR272c","YBR272C",null,null,0.036086515,1.49,0.030458031,1.57]
["9924_at","Metalloprotease involved, with homolog Axl1p, in N-terminal processing of pro-a-factor to the mature form; member of the insulin-degrading enzyme family","STE23","YLR389c","YLR389C",null,null,0.038251188,1.54,0.040215775,1.57]
["10534_at","---","---","YKR017c","YKR017C",null,null,0.03692036,1.61,0.04702148,1.57]
["7955_at","cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk3p","TPK2","YPL203w","YPL203W",null,null,0.035131406,1.63,0.04792673,1.57]
["9493_at","Protein kinase required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta","RIM11","YMR139w","YMR139W",null,null,0.027793137,1.66,0.042446047,1.57]
["7156_at","Protein containing SH3-domains, involved in establishing cell polarity and morphogenesis; functions as a scaffold protein for complexes that include Cdc24p, Ste5p, Ste20p, and Rsr1p","BEM1","YBR200w","YBR200W",{"$nulls":4},0.032054007,1.57]
["9337_at","U2-snRNP associated splicing factor that forms extensive associations with the branch site-3' splice site-3' exon region upon prespliceosome formation; similarity to the mammalian U2 snRNP-associated splicing factor SAP155","HSH155","YMR288w","YMR288W",{"$nulls":4},0.03071439,1.57]
["9778_at","Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencing; implicated in the mitotic exit network through regulation of Cdc14p localization; paralog of Zds1p","ZDS2","YML109w","YML109W",null,null,0.047120545,1.44,0.032862578,1.56]
["9454_at","Protein of unknown function involved in ER-associated protein degradation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YMR184W is not an essential gene","ADD37","YMR184w","YMR184W",null,null,0.04719973,1.52,0.04702148,1.56]
["8377_at","Broad-specificity lysophospholipid acyltransferase, part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids","ALE1","YOR175c","YOR175C",null,null,0.03420884,1.57,0.04081008,1.56]
["4241_at","3-ketoacyl-CoA thiolase with broad chain length specificity, cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids","POT1","YIL160c","YIL160C",null,null,0.022959862,1.7,0.040919054,1.56]
["4963_at","Acyl-CoA-binding protein, transports newly synthesized acyl-CoA esters from fatty acid synthetase (Fas1p-Fas2p) to acyl-CoA-consuming processes","ACB1","YGR037c","YGR037C",{"$nulls":4},0.048997063,1.56]
["4758_at","Protein that functions in a complex with Kel1p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate","KEL2","YGR238c","YGR238C",null,null,0.04785071,1.45,0.03636863,1.55]
["6669_at","Plasma membrane glucose sensor that regulates glucose transport; has 12 predicted transmembrane segments; long cytoplasmic C-terminal tail is required for low glucose induction of hexose transporter genes HXT2 and HXT4","SNF3","YDL194w","YDL194W",null,null,0.035131406,1.48,0.029737087,1.55]
["4176_at","Integral ER membrane protein with type-III transmembrane domains; mutations cause defects in cortical ER morphology in both the mother and daughter cells","ICE2","YIL090w","YIL090W",null,null,0.030912241,1.55,0.036039323,1.55]
["5266_at","Essential nuclear envelope integral membrane protein required for nuclear transport; depletion alters nucleoporin distribution and nuclear envelope morphology, suggesting a role in the spatial organization of nuclear pores","BRR6","YGL247w","YGL247W",null,null,0.03909053,1.57,0.04865961,1.55]
["10374_at","---","---","YLL056c","YLL056C",null,null,0.030126877,1.57,0.037576444,1.55]
["5327_at","Subunit alpha of assimilatory sulfite reductase, which converts sulfite into sulfide","MET10","YFR030w","YFR030W",null,null,0.04730984,1.42,0.03214615,1.54]
["6373_g_at","Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase","DNF2","YDR093w","YDR093W",null,null,0.041143574,1.47,0.034823235,1.54]
["7463_at","Subunit of the nuclear pore complex (NPC), required for NPC localization of specific nucleoporins; involved in nuclear envelope permeability and chromosome segregation; has similar to Nup157p; essential role, with Nup157p, in NPC assembly","NUP170","YBL079w","YBL079W",null,null,0.032224666,1.57,0.040738534,1.54]
["10699_at","One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization","MYO3","YKL129c","YKL129C",null,null,0.029339138,1.59,0.04141803,1.54]
["4220_at","Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane","OM45","YIL136w","YIL136W",null,null,0.019323736,1.71,0.04025058,1.54]
["5338_at","---","---","YFR039c","YFR039C",{"$nulls":4},0.04081008,1.54]
["11112_at","Subunit of DNA Polymerase II Epsilon complex; has BRCT domain, required on the prereplicative complex at replication origins for loading DNA polymerases, also required for S/M checkpoint control; activates Mec1p kinase activity","DPB11","YJL090c","YJL090C",null,null,0.0487613,1.48,0.044123042,1.53]
["4169_at","Putative aminophospholipid translocase (flippase) involved in endocytosis and vacuolar biogenesis; localizes to endosomes and the Golgi aparatus","NEO1","YIL048w","YIL048W",null,null,0.03900883,1.52,0.042577285,1.53]
["11073_at","Essential structural subunit of the nuclear pore complex (NPC), localizes to the nuclear periphery of nuclear pores, homologous to human p205","NUP192","YJL039c","YJL039C",null,null,0.028685216,1.6,0.042501356,1.53]
["7897_at","Telobox-containing general regulatory factor; binds to TTAGGG repeats within subtelomeric anti-silencing regions (STARs) and possibly throughout the genome and mediates their insulating capacity by blocking silent chromatin propagation","TBF1","YPL128c","YPL128C",null,null,0.02996325,1.64,0.049770772,1.53]
["6788_at","Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor","CDC39","YCR093w","YCR093W",null,null,0.022983344,1.66,0.04081008,1.53]
["6670_at","Putative prenyltransferase, required for cell viability; proposed to be involved in protein trafficking because tet-repressible mutant shows accumulation of hypoglycosylated forms of CPY","NUS1","YDL193w","YDL193W",{"$nulls":4},0.033125088,1.53]
["8549_at","Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger","HRD1","YOL013c","YOL013C",null,null,0.045962144,1.42,0.032862578,1.52]
["5305_at","Delta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER","RET2","YFR051c","YFR051C",null,null,0.044946037,1.48,0.042501356,1.52]
["4314_at","Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the RP; binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein","RPN10","YHR200w","YHR200W",null,null,0.041738868,1.49,0.04224675,1.52]
["6816_at","Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains","ERS1","YCR075c","YCR075C",null,null,0.046373643,1.5,0.04728336,1.52]
["9050_at","---","---","YNL208w","YNL208W",null,null,0.035131406,1.54,0.04312308,1.52]
["11219_at","AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; involved in TGN-endosome transport; physically interacts with AP-1; similar to the mammalian p200; may interact with ribosomes; YJL207C is a non-essential gene","LAA1","YJL207c","YJL207C",null,null,0.03618764,1.57,0.04954544,1.52]
["5394_at","Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules","TUB2","YFL037w","YFL037W",null,null,0.019323736,1.6,0.030699031,1.52]
["9142_at","Peripheral membrane protein with a role in endocytosis and vacuole integrity, interacts with Arl1p and localizes to the endosome; member of the Sec7p family of proteins","MON2","YNL297c","YNL297C",null,null,0.030397262,1.62,0.049442615,1.52]
["6566_at","Vacuolar protein that plays a critical role in the tethering steps of vacuolar membrane fusion by facilitating guanine nucleotide exchange on small guanosine triphosphatase Ypt7p","VAM6","YDL077c","YDL077C",null,null,0.02153654,1.65,0.04081008,1.52]
["4480_at","Divalent metal ion transporter involved in manganese homeostasis; has broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins","SMF2","YHR050w","YHR050W",null,null,0.0480002,1.43,0.038846977,1.51]
["7179_at","Acyl-coenzymeA:ethanol O-acyltransferase that plays a minor role in medium-chain fatty acid ethyl ester biosynthesis; possesses short-chain esterase activity; localizes to lipid particles and the mitochondrial outer membrane","EHT1","YBR177c","YBR177C",null,null,0.041068494,1.49,0.042446047,1.51]
["6016_at","E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators; involved in degradation of excess histones","TOM1","YDR457w","YDR457W",null,null,0.04079269,1.5,0.04277993,1.51]
["10218_at","Lysophosphatidic acid acyltransferase, responsible for enhanced phospholipid synthesis during organic solvent stress; null displays increased sensitivity to Calcofluor white; highly expressed during organic solvent stress","ICT1","YLR099c","YLR099C",null,null,0.040639192,1.53,0.04954544,1.51]
["7059_at","Vacuolar aminopeptidase Y, processed to mature form by Prb1p","APE3","YBR286w","YBR286W",null,null,0.023352792,1.59,0.03639737,1.51]
["6494_at","Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex, stimulated by SUMO-modified substrates; contains a RING domain and two SIMs (SUMO-interacting motifs); forms SUMO-dependent nuclear foci, including DNA repair centers","SLX5","YDL013w","YDL013W",{"$nulls":4},0.04866978,1.51]
["4742_at","---","---","YGR266w","YGR266W",{"$nulls":4},0.0472941,1.51]
["4088_at","---","---","YIR007w","YIR007W",{"$nulls":4},0.04030816,1.51]
["8597_at","Nuclear protein, putative RNA polymerase II elongation factor; isolated as Pob3p/Spt16p-binding protein","PSH1","YOL054w","YOL054W",{"$nulls":4},0.036039323,1.51]
["8025_at","Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter","MDL2","YPL270w","YPL270W",{"$nulls":4},0.039962176,1.51]
["5651_at","---","---","YER078c","YER078C",null,null,0.036086515,1.52,0.0433345,1.5]
["5179_at","Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation; delivered to the vacuole in a novel pathway separate from the secretory pathway","AMS1","YGL156w","YGL156W",null,null,0.03692036,1.52,0.046511646,1.5]
["9772_at","Component of the mannan polymerase I, which contains Van1p and Mnn9p and is involved in the first steps of mannan synthesis; mutants are vanadate-resistant","VAN1","YML115c","YML115C",null,null,0.037908208,1.53,0.047575828,1.5]
["6085_at","Actin-associated protein, interacts with Rvs161p to regulate actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; homolog of mammalian amphiphysin","RVS167","YDR388w","YDR388W",null,null,0.035472132,1.54,0.04832616,1.5]
["7405_at","Key endocytic protein involved in a network of interactions with other endocytic proteins, binds membranes in a ubiquitin-dependent manner, may also bind ubiquitinated membrane-associated proteins","EDE1","YBL047c","YBL047C",null,null,0.021419922,1.57,0.032862578,1.5]
["5135_at","Mitochondrial protein required for respiratory growth; mutant phenotype and genetic interactions suggest a role in delivering mt mRNAs to ribosomes; located on matrix face of the inner membrane and loosely associated with mitoribosomes","RMD9","YGL107c","YGL107C",{"$nulls":4},0.042446047,1.5]
["4747_at","Putative RNA helicase related to Ski2p, involved in translation inhibition of non-poly(A) mRNAs; required for repressing propagation of dsRNA viruses","SLH1","YGR271w","YGR271W",{"$nulls":4},0.034823235,1.5]
["4196_at","Nucleoporin, subunit of the nuclear pore complex that is found exclusively on the cytoplasmic side, forms a subcomplex with Nup82p and Nsp1p, required for mRNA export","NUP159","YIL115c","YIL115C",{"$nulls":4},0.03782841,1.5]
["11083_at","Subunit of the multiprotein cohesin complex required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member","SMC3","YJL074c","YJL074C",{"$nulls":4},0.04702148,1.5]
["8594_at","---","---","YOL057w","YOL057W",{"$nulls":4},0.046224054,1.5]
["5713_at","DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase, associates with lariat intermediates before the second catalytic step of splicing; mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes","PRP22","YER013w","YER013W",null,null,0.03253533,1.52,0.041911382,1.49]
["11046_at","Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches","BBC1","YJL020C","YJL021C",null,null,0.03526985,1.52,0.04284326,1.49]
["8354_at","Putative cysteine protease similar to mammalian caspases; involved in regulation of apoptosis upon hydrogen peroxide treatment; proposed to be involved in cell cycle progression","MCA1","YOR197w","YOR197W",null,null,0.03329286,1.54,0.046251643,1.49]
["7333_at","Galactokinase, phosphorylates alpha-D-galactose to alpha-D-galactose-1-phosphate in the first step of galactose catabolism; expression regulated by Gal4p","GAL1","YBR020w","YBR020W",{"$nulls":4},0.044123042,1.49]
["4973_at","One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA domain of TFIIIC that binds BoxA DNA promoter sites of tRNA and similar genes; has TPR motifs; human homolog is TFIIIC-102","TFC4","YGR047c","YGR047C",{"$nulls":4},0.04702148,1.49]
["10349_at","Essential subunit of the Mms21-Smc5-Smc6 complex; nuclear protein required for DNA repair and growth; has a nonstructural role in the maintenance of chromosomes","NSE1","YLR007w","YLR007W",{"$nulls":4},0.04346399,1.49]
["5367_at","Dihydrolipoamide dehydrogenase, the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes","LPD1","YFL018c","YFL018C",null,null,0.045320865,1.46,0.04702148,1.48]
["11118_at","Protein proposed to regulate the endocytosis of plasma membrane proteins; interacts with the cyclin Pcl7p and ubiquitin ligase Rsp5p; phosphorylated by the cyclin-CDK complex, Pcl7p-Pho85p; mRNA is cell cycle regulated, peaking in M phase","ALY2","YJL084c","YJL084C",null,null,0.034512978,1.48,0.038846977,1.48]
["6341_at","Protein required for nuclear migration, localizes to the mother cell cortex and the bud tip; may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex","NUM1","YDR150w","YDR150W",null,null,0.028161952,1.53,0.040215775,1.48]
["5384_at","Vacuolar membrane protein involved in vacuolar polyphosphate accumulation; functions as a regulator of vacuolar H+-ATPase activity and vacuolar transporter chaperones; involved in protein localization and non-autophagic vacuolar fusion","VTC2","YFL004w","YFL004W",{"$nulls":4},0.045333907,1.48]
["10681_at","Vacuolar aminopeptidase yscI; zinc metalloproteinase that belongs to the peptidase family M18; often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway","LAP4","YKL103c","YKL103C",{"$nulls":4},0.042881217,1.48]
["10693_at","Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting","APL2","YKL135c","YKL135C",{"$nulls":4},0.038771104,1.47]
["9031_at","Protein kinase that stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation","NPR1","YNL183c","YNL183C",{"$nulls":4},0.044815972,1.47]
["4370_at","Component of the U4/U6-U5 snRNP complex, involved in the second catalytic step of splicing; mutations of human Prp8 cause retinitis pigmentosa","PRP8","YHR165c","YHR165C",null,null,0.03909053,1.44,0.040175855,1.46]
["4806_at","Protein of unknown function, required for survival upon exposure to K1 killer toxin","FYV8","YGR196c","YGR196C",{"$nulls":4},0.04702148,1.46]
["10020_at","Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway; required for normal vacuole morphology, cell wall integrity, and actin cytoskeleton organization","STT4","YLR305c","YLR305C",{"$nulls":4},0.042501356,1.46]
["4228_at","DNA repair and TFIIH regulator, required for both nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription; involved in telomere maintenance","MET18","YIL128w","YIL128W",{"$nulls":4},0.041897196,1.45]
["7770_at","Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase), cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis","ERG10","YPL028w","YPL028W",{"$nulls":4},0.042446047,1.45]
["9152_at","Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p forms the COPI coat; involved in ER to Golgi transport of selective cargo","SEC21","YNL287w","YNL287W",null,null,0.04467087,1.4,0.04188936,1.44]
["10124_at","UDP-glucose:sterol glucosyltransferase, conserved enzyme involved in synthesis of sterol glucoside membrane lipids; in contrast to ATG26 from P. pastoris, S. cerevisiae ATG26 is not involved in autophagy","ATG26","YLR189c","YLR189C",null,null,0.036887113,1.45,0.044850536,1.44]
["7815_at","Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family, localized to the cortex of mother cells but not to daughter cells","YTA6","YPL074w","YPL074W",null,null,0.03984505,1.46,0.049028154,1.44]
["5059_at","One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle","RPT6","YGL048c","YGL048C",{"$nulls":4},0.049905967,1.44]
["5771_at","Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance","CAN1","YEL063c","YEL063C",null,null,0.046512563,1.42]
["4746_at","Protein that localizes to chromatin and has a role in regulation of histone gene expression; has a bromodomain-like region that interacts with the N-terminal tail of histone H3, and an ATPase domain; potentially phosphorylated by Cdc28p","YTA7","YGR270w","YGR270W",null,null,0.045774836,1.43]
["9369_at","Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional homolog of Bul2p, disruption causes temperature-sensitive growth, overexpression causes missorting of amino acid permeases","BUL1","YMR275c","YMR275C",null,null,0.048727226,1.43]
["8691_at","Lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, also known as DMRL synthase); catalyzes synthesis of immediate precursor to riboflavin","RIB4","YOL143c","YOL143C",null,null,0.048727226,1.43]
["5086_at","Subunit of SAGA histone acetyltransferase complex; involved in formation of the preinitiation complex assembly at promoters; null mutant displays defects in premeiotic DNA synthesis","SGF73","YGL066w","YGL066W",null,null,0.04116366,1.44]
["4376_at","Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes; mediates the conjugation of Atg12p with Atg5p and Atg8p with phosphatidylethanolamine, required steps in autophagosome formation","ATG7","YHR171w","YHR171W",null,null,0.048190325,1.45]
["7647_at","---","---","YPR115w","YPR115W",null,null,0.045461163,1.45]
["7326_at","Ubiquitin-specific protease that specifically disassembles unanchored ubiquitin chains; involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; similar to human isopeptidase T","UBP14","YBR058c","YBR058C",null,null,0.041642867,1.46]
["6339_at","Dihydrolipoyl transsuccinylase, component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA in the TCA cycle; phosphorylated","KGD2","YDR148c","YDR148C",null,null,0.04347296,1.46]
["5004_at","Zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes","PDR1","YGL013c","YGL013C",null,null,0.04533356,1.46]
["8515_at","Protein containing a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern","CUE5","YOR042w","YOR042W",null,null,0.048911855,1.46]
["7354_at","Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton; interacts with proteins regulating actin dynamics and proteins required for endocytosis; found in the nucleus and cell cortex; has 3 SH3 domains","SLA1","YBL007c","YBL007C",null,null,0.03896845,1.47]
["10684_at","---","---","YKL100c","YKL100C",null,null,0.035909276,1.47]
["8004_at","Possible rhomboid protease, has similarity to eukaryotic rhomboid proteases including Pcp1p","RBD2","YPL246c","YPL246C",null,null,0.040639192,1.47]
["6893_at","Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains six WD40 repeats; computational analysis suggests that Gid7p and Moh1p have similar functions","GID7","YCL039w","YCL039W",null,null,0.039766785,1.48]
["10416_at","Glutathione S-transferase capable of homodimerization; functional overlap with Gtt2p, Grx1p, and Grx2p","GTT2","YLL060c","YLL060C",null,null,0.048343055,1.48]
["6912_at","Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding","BUD3","YCL014w","YCL014W",null,null,0.037118897,1.49]
["5149_at","---","---","YGL140c","YGL140C",null,null,0.044571914,1.49]
["4959_at","Catalytic subunit of 1,3-beta-glucan synthase, involved in formation of the inner layer of the spore wall; activity positively regulated by Rho1p and negatively by Smk1p; has similarity to an alternate catalytic subunit, Fks1p (Gsc1p)","GSC2","YGR032w","YGR032W",null,null,0.046953686,1.49]
["4456_at","Protein with carboxyl methyl esterase activity that may have a role in demethylation of the phosphoprotein phosphatase catalytic subunit; also identified as a small subunit mitochondrial ribosomal protein","PPE1","YHR075c","YHR075C",null,null,0.044252113,1.49]
["7750_at","Protein that acts together with Uba3p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation","ULA1","YPL003w","YPL003W",null,null,0.04104293,1.49]
["10071_at","Transcription factor; targets include ATP-binding cassette (ABC) transporters, major facilitator superfamily transporters, and other genes involved in the pleiotropic drug resistance (PDR) phenomenon","PDR8","YLR266c","YLR266C",null,null,0.045670368,1.5]
["6887_at","Acetate transporter required for normal sporulation; phosphorylated in mitochondria","ADY2","YCR010c","YCR010C",null,null,0.047402546,1.51]
["10731_at","Protein of unknown function; undergoes sumoylation; transcription induced under cell wall stress; protein levels are reduced under anaerobic conditions; originally thought to be a mitochondrial ribosomal protein based on sequence analysis","MRP8","YKL142w","YKL142W",null,null,0.049629055,1.51]
["7779_at","Vacuolar membrane protein involved in vacuolar polyphosphate accumulation; functions as a regulator of vacuolar H+-ATPase activity and vacuolar transporter chaperones; involved in non-autophagic vacuolar fusion","VTC3","YPL019c","YPL019C",null,null,0.04318158,1.51]
["7592_at","Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs)","NCE102","YPR149w","YPR149W",null,null,0.04665735,1.51]
["3436_f_at","---","---","tQ(UUG)D1","TQ(UUG)D1",null,null,0.045403827,1.52]
["6920_at","Zinc metalloendopeptidase, found in the cytoplasm and intermembrane space of mitochondria; with Cym1p, involved in degradation of mitochondrial proteins and of presequence peptides cleaved from imported proteins","PRD1","YCL057w","YCL057W",null,null,0.03984505,1.52]
["6332_at","Protein of unknown function, essential for viability, involved in establishing cellular polarity and morphogenesis; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies","DOP1","YDR141c","YDR141C",null,null,0.047389682,1.52]
["5343_at","Cys-Gly metallo-di-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)","DUG1","YFR044c","YFR044C",null,null,0.042979635,1.52]
["7264_at","Plasma membrane protein that may be involved in osmotolerance, localizes to the mother cell in small-budded cells and to the bud in medium- and large-budded cells; mRNA is transported to the bud tip by an actomyosin-driven process","IST2","YBR086c","YBR086C",null,null,0.04279086,1.53]
["6820_at","Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in glucose repression","SRB8","YCR081w","YCR081W",null,null,0.04318706,1.53]
["4849_at","---","---","YGR149w","YGR149W",null,null,0.04466735,1.53]
["10483_at","Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation","FLO10","YKR102w","YKR102W",null,null,0.045746475,1.53]
["9555_at","Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes","MOT3","YMR070w","YMR070W",null,null,0.041143574,1.53]
["9564_at","Subunit of a complex with Ctf8p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint","CTF18","YMR078c","YMR078C",null,null,0.046512563,1.53]
["6847_g_at","---","---","YCR061w","YCR061W",null,null,0.047248643,1.54]
["6239_at","mRNA 3' end processing factor, essential component of cleavage and polyadenylation factor IA (CF IA), involved in pre-mRNA 3' end processing and in transcription termination; binds C-terminal domain of largest subunit of RNA pol II (Rpo21p)","PCF11","YDR228c","YDR228C",null,null,0.036086515,1.54]
["5228_at","Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Pmd1p, for growth under alkaline conditions","MDS3","YGL197w","YGL197W",null,null,0.040639192,1.54]
["9757_at","Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria and is phosphorylated","MSC1","YML128c","YML128C",null,null,0.032224666,1.54]
["11297_at","Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated","YAT1","YAR035w","YAR035W",null,null,0.041279823,1.55]
["7327_at","Ser-Thr protein kinase, member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization","AKL1","YBR059c","YBR059C",null,null,0.032324918,1.55]
["7078_at","---","---","YBR085c-a","YBR085c-a",null,null,0.030675923,1.55]
["5990_at","---","---","YDR476c","YDR476C",null,null,0.038197506,1.55]
["4958_at","---","---","YGR031w","YGR031W",null,null,0.04533356,1.55]
["4285_at","---","---","YIL166c","YIL166C",null,null,0.037118897,1.57]
["6004_at","Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for stable association of Srb10p-Srb11p kinase; essential for transcriptional regulation","SSN2","YDR443c","YDR443C",null,null,0.03931688,1.58]
["5026_at","---","---","YGL036w","YGL036W",null,null,0.03344852,1.58]
["10525_at","Dihydrosphingosine 1-phosphate phosphatase, membrane protein involved in sphingolipid metabolism; has similarity to Lcb3p","YSR3","YKR053c","YKR053C",null,null,0.044571914,1.58]
["9908_at","Component of the ESCRT-II complex; contains the GLUE (GRAM Like Ubiquitin binding in EAP45) domain which is involved in interactions with ESCRT-I and ubiquitin-dependent sorting of proteins into the endosome","VPS36","YLR417w","YLR417W",null,null,0.04318706,1.58]
["6357_at","Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin2p","KIN1","YDR122w","YDR122W",null,null,0.036086515,1.59]
["4952_at","---","---","YGR071c","YGR071C",null,null,0.023557536,1.59]
["4138_at","Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA), a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation","BCY1","YIL033c","YIL033C",null,null,0.036831696,1.59]
["6633_at","Cardiolipin synthase; produces cardiolipin, which is a phospholipid of the mitochondrial inner membrane that is required for normal mitochondrial membrane potential and function; also required for normal vacuolar ion homeostasis","CRD1","YDL142c","YDL142C",null,null,0.028986571,1.6]
["7098_at","F-Box protein involved in proteasome-dependent degradation of Aah1p during entry of cells into quiescence; interacts with Skp1","SAF1","YBR280c","YBR280C",null,null,0.0487613,1.61]
["4791_at","Activator of meiotic anaphase promoting complex (APC/C); Cdc20p family member; required for initiation of spore wall assembly; required for Clb1p degradation during meiosis","AMA1","YGR225w","YGR225W",null,null,0.045767087,1.61]
["10723_at","Mitochondrial NADH-cytochrome b5 reductase, involved in ergosterol biosynthesis","MCR1","YKL150w","YKL150W",null,null,0.03984505,1.61]
["8949_at","ADP/ATP transporter; member of the Ca2+-binding subfamily of the mitochondrial carrier family, with two EF-hand motifs; Pet9p and Sal1p have an overlapping function critical for viability; polymorphic in different S. cerevisiae strains","SAL1","YNL083w","YNL083W",null,null,0.048727226,1.61]
["8348_i_at","Transporter of thiamine or related compound; shares sequence similarity with Thi7p","THI72","YOR192c","YOR192C",null,null,0.041143574,1.61]
["4225_at","Forkhead family transcription factor with a minor role in the expression of G2/M phase genes; negatively regulates transcriptional elongation; positive role in chromatin silencing at HML and HMR; regulates donor preference during switching","FKH1","YIL131c","YIL131C",null,null,0.020994212,1.63]
["10851_at","---","---","YJR149w","YJR149W",null,null,0.0480002,1.63]
["9355_at","Regulatory subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway","TPS3","YMR261c","YMR261C",null,null,0.038763218,1.63]
["8267_at","Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor?Rakeb syndrome","YPK9","YOR291w","YOR291W",null,null,0.036086515,1.64]
["5425_at","Low-affinity amino acid permease, may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions; transcription is induced under conditions of sulfur limitation; plays a role in regulating Ty1 transposition","AGP3","YFL055w","YFL055W",null,null,0.045245778,1.65]
["9285_at","---","---","YMR320w","YMR320W",null,null,0.019466328,1.65]
["10572_at","Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; has 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities","FOX2","YKR009c","YKR009C",null,null,0.042742193,1.68]
["9356_at","---","---","YMR262w","YMR262W",null,null,0.025124025,1.68]
["10179_at","---","---","YLR149c","YLR149C",null,null,0.037467405,1.69]
["5046_at","Karyopherin beta, responsible for import of the Toa1p-Toa2p complex into the nucleus; binds to nucleoporins Nup1p and Nup2p; may play a role in regulation of pleiotropic drug resistance","KAP122","YGL016w","YGL016W",null,null,0.044815745,1.71]
["10391_at","Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated with membranes; homologous to human COH1; involved in sporulation, vacuolar protein sorting and protein-Golgi retention","VPS13","YLL040c","YLL040C",null,null,0.043644145,1.71]
["9107_at","Peripheral membrane protein required for vesicle formation during autophagy, pexophagy, and the cytoplasm-to-vaucole targeting (Cvt) pathway; involved in Atg9p cycling between the phagophore assembly site and mitochondria","ATG2","YNL242w","YNL242W",null,null,0.04533356,1.72]
["5398_at","Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; substrate of Pho80p-Pho85p kinase","RIM15","YFL033c","YFL033C",null,null,0.026403429,1.73]
["10099_at","Protein required for ethanol metabolism; induced by heat shock and localized to the inner mitochondrial membrane; homologous to mammalian peroxisomal membrane protein Mpv17","SYM1","YLR251w","YLR251W",null,null,0.037277464,1.73]
["9765_at","NADH:ubiquinone oxidoreductase, transfers electrons from NADH to ubiquinone in the respiratory chain but does not pump protons, in contrast to the higher eukaryotic multisubunit respiratory complex I; phosphorylated; homolog of human AMID","NDI1","YML120c","YML120C",null,null,0.04785114,1.74]
["9004_at","Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; member of the Nudix hydrolase family","DCP2","YNL118c","YNL118C",null,null,0.04332292,1.75]
["7757_at","Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux; expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p","HAL1","YPR005c","YPR005C",null,null,0.032923836,1.75]
["6556_at","Mitochondrial external NADH dehydrogenase, catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p are involved in providing the cytosolic NADH to the mitochondrial respiratory chain","NDE2","YDL085w","YDL085W",null,null,0.031186797,1.76]
["6729_at","Substrate of the Hub1p ubiquitin-like protein that localizes to the shmoo tip (mating projection); mutants are defective for mating projection formation, thereby implicating Hbt1p in polarized cell morphogenesis","HBT1","YDL223c","YDL223C",null,null,0.03931688,1.76]
["6333_at","Peroxisomal signal receptor for the N-terminal nonapeptide signal (PTS2) of peroxisomal matrix proteins; WD repeat protein; defects in human homolog cause lethal rhizomelic chondrodysplasia punctata (RCDP)","PEX7","YDR142c","YDR142C",null,null,0.048937034,1.76]
["10189_at","---","---","YLR164w","YLR164W",null,null,0.040401895,1.77]
["6803_at","---","---","YCR061W","YCR062W",null,null,0.016103525,1.78]
["6704_at","Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily","RTN2","YDL204w","YDL204W",null,null,0.027212571,1.78]
["4972_at","Mitochondrial protein involved in protein import into the mitochondrial matrix; maintains the functional integrity of the TIM23 protein translocator complex; viability of null mutant is strain-dependent; mRNA is targeted to the bud","TAM41","YGR046w","YGR046W",null,null,0.03562021,1.78]
["4209_at","Transcriptional repressor that binds to promoter sequences of the cyclin genes, CYS3, and SMF2; expression is induced by stress or starvation during mitosis, and late in meiosis; member of the Swi4p/Mbp1p family; potential Cdc28p substrate","XBP1","YIL101c","YIL101C",null,null,0.036086515,1.79]
["3947_at","---","---","YKL033w-a","YKL033W-A",null,null,0.047031227,1.81]
["8195_at","Meiosis-specific serine/threonine protein kinase, functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids","MEK1","YOR351c","YOR351C",null,null,0.03562021,1.81]
["6479_at","---","---","YDR018c","YDR018C",null,null,0.0410955,1.82]
["7789_at","Zinc-finger protein of unknown function","LEE1","YPL054w","YPL054W",null,null,0.025124025,1.84]
["6714_at","Protein required for spore wall formation, thought to mediate assembly of a Don1p-containing structure at the leading edge of the prospore membrane via interaction with spindle pole body components; potentially phosphorylated by Cdc28p","ADY3","YDL239c","YDL239C",null,null,0.048937034,1.85]
["5774_at","Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation","PRB1","YEL060c","YEL060C",null,null,0.035706777,1.86]
["10908_at","---","---","YJR115w","YJR115W",null,null,0.021542588,1.89]
["9310_at","Ubiquitin-specific protease that may play a role in ubiquitin precursor processing","UBP15","YMR304w","YMR304W",null,null,0.030397262,1.9]
["5052_at","Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria","OLE1","YGL055w","YGL055W",null,null,0.046373643,1.91]
["10447_s_at","Putative serine/threonine protein kinase that regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein","PTK1","YKL198c","YKL198C",null,null,0.032324918,1.93]
["7549_g_at","MAL-activator protein, part of complex locus MAL3; nonfunctional in genomic reference strain S288C","MAL33","YPR196w","YPR196W",null,null,0.034512978,1.93]
["11048_at","Nuclear envelope protein required for SPB duplication and nuclear fusion; localizes to the SPB half bridge and at telomeres during meiosis; required with Ndj1p and Csm4p for meiotic bouquet formation and telomere-led rapid prophase movement","MPS3","YJL019w","YJL019W",null,null,0.037118897,1.96]
["6846_at","---","---","YCR061w","YCR061W",null,null,0.0487613,1.99]
["7686_at","Protein that acts together with Ula1p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation; GFP-fusion protein localizes to the cytoplasm in a punctate pattern","UBA3","YPR066w","YPR066W",null,null,0.037277464,1.99]
["6380_at","Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p","TVP15","YDR100w","YDR100W",null,null,0.03329286,2.04]
["10930_at","Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated proteins; involved in localizing the Arp2/3 complex to mitochondria; overexpression causes increased sensitivity to benomyl","JSN1","YJR091c","YJR091C",null,null,0.049815755,2.04]
["7488_at","Kynurenine 3-mono oxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p; putative therapeutic target for Huntington disease","BNA4","YBL098w","YBL098W",null,null,0.03427987,2.05]
["5789_at","Threonine aldolase, catalyzes the cleavage of L-allo-threonine and L-threonine to glycine; involved in glycine biosynthesis","GLY1","YEL046c","YEL046C",null,null,0.048937034,2.08]
["10677_at","---","---","YKL107w","YKL107W",null,null,0.036086515,2.09]
["9098_at","RNA-binding protein that interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p), preferentially at phosphorylated Ser5; required for transcription termination and 3' end maturation of nonpolyadenylated RNAs","NRD1","YNL251c","YNL251C",null,null,0.03984505,2.11]
["9289_at","---","---","YMR324c","YMR324C",null,null,0.039004453,2.12]
["4461_r_at","Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Mei5p; proposed to be an assembly factor for Dmc1p","SAE3","YHR079c-a","YHR079C-A",null,null,0.03909053,2.16]
["4876_at","---","---","YGR131w","YGR131W",null,null,0.029596789,2.49]
["6398_at","Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway","TPS2","YDR074w","YDR074W",null,null,0.023661098,3.44]
[]
[]
[]
[]
[]
[null,"also identified as being beneficial to survival of desiccation in the phenomics analysis"]
[]
[null,"protein kinase"]
[null,"transcription factor"]

{"sheet":"Significantly downregulated","index":2,"n_rows":347,"n_cols":11,"rows_kept":347,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["Probe.Set.ID","GENE_TITLE","GENE_SYMBOL",null,"SYSTEMATIC_ID","adj.p.values..0vs.30","Fold-Change..0vs.30","adj.p.values..0vs.60","Fold-Change..0vs.60","adj.p.values..0vs.120","Fold-Change..0vs.120"]
["5764_at","RNA binding protein, part of U3 snoRNP involved in rRNA processing, part of U4/U6-U5 tri-snRNP involved in mRNA splicing, similar to human 15.5K protein","SNU13","YEL026w","YEL026W",null,null,0.008267137,6.38,0.010989325,6]
["4860_at","Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis","NSR1","YGR159c","YGR159C",null,null,0.025417518,6.73,0.041728884,5.33]
["8246_s_at","Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA","NOP58","YOR309c","YOR309C",null,null,0.013970491,5.45,0.027536953,4.05]
["10598_at","Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus","MRT4","YKL009w","YKL009W",null,null,0.004507823,4.64,0.008070919,3.85]
["4748_at","---","---","YGR272c","YGR272C",null,null,0.006657839,3.95,0.010061595,3.61]
["6329_at","Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)","RUB1","YDR139c","YDR139C",{"$nulls":4},0.048369627,3.43]
["8963_at","RNA polymerase subunit, common to RNA polymerases I and III","RPC19","YNL113w","YNL113W",null,null,0.004462174,3.77,0.007345175,3.35]
["8263_at","---","---","YOR287c","YOR287C",null,null,0.012073058,2.91,0.011694316,3.11]
["10947_at","RNA polymerase I subunit A12.2; contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex","RPA12","YJR063w","YJR063W",null,null,0.004176672,3.72,0.00789221,3.1]
["4229_at","Putative protein of unknown function; identified in a screen for mutants with decreased levels of rDNA transcription; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; predicted to be involved in ribosome biogenesis","RRT14","YIL127c","YIL127C",null,null,0.005579652,3.21,0.008070919,3.06]
["7348_at","Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, thus facilitating nuclear export of these proteins; required for viability of npl3 mutants","HMT1","YBR034c","YBR034C",null,null,0.011786537,3.18,0.01714258,2.93]
["11190_at","RNA polymerase I subunit A34.5","RPA34","YJL148w","YJL148W",null,null,0.00542073,3.5,0.010989325,2.92]
["11302_at","---","---","YAR053w","YAR053W",null,null,0.019476412,2.65,0.021514155,2.81]
["8565_at","Essential nucleolar protein that is a component of the SSU (small subunit) processome involved in 40S ribosomal subunit biogenesis; has homology to PINc domain protein Fcf1p, although the PINc domain of Utp23p is not required for function","UTP23","YOR004w","YOR004W",null,null,0.019466328,2.63,0.021706928,2.76]
["7697_i_at","---","---","YPR077c","YPR077C",null,null,0.005322267,2.85,0.007641272,2.75]
["10155_at","Pseudouridine synthase catalytic subunit of box H/ACA small nucleolar ribonucleoprotein particles (snoRNPs), acts on both large and small rRNAs and on snRNA U2; mutations in human ortholog dyskerin cause the disorder dyskeratosis congenita","CBF5","YLR175w","YLR175W",null,null,0.028037488,2.81,0.03639737,2.7]
["10133_at","---","---","YLR198c","YLR198C",null,null,0.007072283,2.77,0.009467186,2.69]
["5571_at","Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein","RPS26B","YER131w","YER131W",null,null,0.011786537,3.75,0.028677335,2.68]
["10936_at","Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein","JJJ3","YJR097w","YJR097W",null,null,0.008267137,2.88,0.011694316,2.67]
["8321_at","RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III","RPB10","YOR210w","YOR210W",null,null,0.003306089,2.82,0.004918494,2.66]
["8524_at","---","---","YOR051c","YOR051C",null,null,0.003748165,3.21,0.00789221,2.66]
["5033_at","Protein involved in nucleolar integrity and processing of the pre-rRNA for the 60S ribosome subunit; transcript is induced in response to cytotoxic stress but not genotoxic stress","CGR1","YGL029w","YGL029W",null,null,0.014202219,3.11,0.027168555,2.57]
["11218_at","Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy","NUC1","YJL208c","YJL208C",null,null,0.003172797,2.96,0.005948845,2.55]
["10277_at","Essential protein required for maturation of 18S rRNA; required for survival upon exposure to K1 killer toxin","FYV7","YLR068w","YLR068W",null,null,0.0234828,2.81,0.03639737,2.54]
["9363_at","Nucleolar protein of unknown function implicated in ribosome biogenesis; TMA23 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes","TMA23","YMR269w","YMR269W",null,null,0.011433553,2.47,0.011694316,2.52]
["5396_at","Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Ap and to rat L22 ribosomal protein","RPL22B","YFL034c-a","YFL034C-A",null,null,0.00526164,2.94,0.010593429,2.5]
["7947_at","Nucleolar protein required for 60S ribosome subunit biogenesis, constituent of 66S pre-ribosomal particles; physically interacts with Nop8p and the exosome subunit Rrp43p","NIP7","YPL211w","YPL211W",null,null,0.019476412,2.67,0.028888363,2.48]
["6185_at","Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p","SRB7","YDR308c","YDR308C",null,null,0.012773143,2.73,0.021230683,2.47]
["7260_at","Ubiquitin-conjugating enzyme (E2), mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response","UBC4","YBR082c","YBR082C",null,null,0.012312659,2.47,0.015085032,2.46]
["8618_at","Putative RNA exonuclease possibly involved in pre-rRNA processing and ribosome assembly","REX4","YOL080c","YOL080C",null,null,0.020927202,2.6,0.030458031,2.42]
["10260_at","Essential nucleolar protein involved in the early steps of 35S rRNA processing; interacts with Faf1p; member of a transcriptionally co-regulated set of genes called the RRB regulon","FCF2","YLR051c","YLR051C",null,null,0.004462174,2.45,0.006150739,2.39]
["11236_at","Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Bp and has similarity to E. coli S8 and rat S15a ribosomal proteins","RPS22A","YJL190c","YJL190C",null,null,0.013651473,3.05,0.03157696,2.38]
["7376_at","---","---","YBL029w","YBL029W",null,null,0.0164224,2.34,0.021063095,2.32]
["6700_at","Nuclear protein related to mammalian high mobility group (HMG) proteins, essential for function of H/ACA-type snoRNPs, which are involved in 18S rRNA processing","NHP2","YDL208w","YDL208W",null,null,0.01777198,2.61,0.02815286,2.32]
["10175_at","Subunit of RNase MRP, which processes pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; unlike most subunits, not shared between RNase MRP and nuclear RNase P","RMP1","YLR145w","YLR145W",null,null,0.011433553,2.33,0.012367917,2.31]
["9038_at","Nucleolar protein found in preribosomal complexes; contains an RNA recognition motif (RRM)","NOP13","YNL175c","YNL175C",null,null,0.018225834,3.01,0.042446047,2.3]
["5612_at","---","---","YER084w","YER084W",null,null,0.023352792,2.07,0.021230683,2.28]
["9023_at","Mating pheromone a-factor, made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA1","MFA2","YNL145w","YNL145W",null,null,0.03295831,2.38,0.042446047,2.28]
["10271_at","Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene RPL22A; diploid mutant displays a weak budding pattern phenotype in a systematic assay","BUD28","YLR062c","YLR062C",null,null,0.030559367,2.44,0.04484607,2.25]
["8319_at","Protein of unknown function that associates with ribosomes","TMA16","YOR252w","YOR252W",null,null,0.011764461,2.64,0.022340296,2.24]
["4818_at","Phosphoserine phosphatase of the phosphoglycerate pathway, involved in serine and glycine biosynthesis, expression is regulated by the available nitrogen source","SER2","YGR208w","YGR208W",null,null,0.019888718,2.55,0.036039323,2.23]
["8665_at","Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain","TRM11","YOL124c","YOL124C",null,null,0.016103525,2.08,0.014536896,2.22]
["9184_at","Protein component of the large (60S) ribosomal subunit, identical to Rpl18Ap and has similarity to rat L18 ribosomal protein","RPL18B","YNL301c","YNL301C",null,null,0.012633189,2.09,0.011694316,2.21]
["10500_at","---","---","YKR075c","YKR075C",null,null,0.021059485,2.08,0.021706928,2.2]
["8813_at","Essential nucleolar protein involved in pre-18S rRNA processing; binds to RNA and stimulates ATPase activity of Dbp8; involved in assembly of the small subunit (SSU) processome","ESF2","YNR054c","YNR054C",null,null,0.011433553,2.69,0.023536323,2.19]
["6695_at","Putative RNA-binding protein implicated in ribosome biogenesis; contains an RNA recognition motif (RRM) and has similarity to hydrophilins; NOP6 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes","NOP6","YDL213c","YDL213C",null,null,0.026841687,2.35,0.040463086,2.18]
["4393_at","RNA polymerase subunit, found in RNA polymerase complexes I, II, and III","RPC10","YHR143w-a","YHR143W-A",null,null,0.01729962,2.24,0.022979526,2.16]
["9027_at","Adenine deaminase (adenine aminohydrolase), converts adenine to hypoxanthine; involved in purine salvage; transcriptionally regulated by nutrient levels and growth phase; Aah1p degraded upon entry into quiescence via SCF and the proteasome","AAH1","YNL141w","YNL141W",null,null,0.018114772,2.49,0.03287144,2.14]
["5082_at","RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site; involved in telomere maintenance","RPB9","YGL070c","YGL070C",null,null,0.024470093,1.99,0.023536323,2.12]
["6286_at","Nuclear protein, possibly involved in regulation of cation stress responses and/or in the establishment of bipolar budding pattern","ATC1","YDR184c","YDR184C",null,null,0.032723133,1.98,0.030458031,2.11]
["11010_at","RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex","RPC17","YJL011c","YJL011C",null,null,0.008267137,2.21,0.011694316,2.1]
["9469_at","Mitochondrial ribosomal protein of the small subunit","MRPS8","YMR158w","YMR158W",null,null,0.01777198,1.98,0.017240513,2.09]
["7772_at","Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway","SKS1","YPL026c","YPL026C",null,null,0.018511113,2,0.019158732,2.09]
["7377_at","---","---","YBL028c","YBL028C",null,null,0.036086515,2,0.036039323,2.09]
["8240_at","---","---","YOR305w","YOR305W",null,null,0.021417374,2.12,0.026785614,2.09]
["9372_at","Non-essential sumoylated protein of unknown function with similarity to components of human SWI/SNF complex including SMRD3; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, nucleus and nucleolus","TRI1","YMR233w","YMR233W",null,null,0.0234828,1.76,0.013976484,2.07]
["10113_at","Protein with a likely role in ribosomal maturation, required for accumulation of wild-type levels of large (60S) ribosomal subunits; binds to the helicase Dbp6p in pre-60S ribosomal particles in the nucleolus","RSA3","YLR221c","YLR221C",null,null,0.011764461,2.01,0.011694316,2.07]
["4914_at","Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes efficient protein folding","PAC10","YGR078c","YGR078C",null,null,0.034647685,2.15,0.044123042,2.07]
["8336_at","RNA polymerase subunit ABC14.5, common to RNA polymerases I, II, and III","RPB8","YOR224c","YOR224C",null,null,0.018511113,1.91,0.016521795,2.06]
["10053_at","Ran GTPase, GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; regulated by Srm1p, Rna1p, Yrb1p, Yrb2p, Yrp4p, Yrb30p, Cse1p and Kap95p; yeast Gsp2p homolog","GSP1","YLR293c","YLR293C",null,null,0.013853301,2.01,0.015286929,2.06]
["10270_at","Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Bp and to rat L22 ribosomal protein","RPL22A","YLR061w","YLR061W",null,null,0.012312659,2.53,0.027868846,2.06]
["8998_at","RNA-binding protein required for the assembly of box H/ACA snoRNPs and thus for pre-rRNA processing, forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; similar to Gar1p","NAF1","YNL124w","YNL124W",null,null,0.02185912,2.02,0.02477741,2.05]
["8920_i_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Ap and has similarity to E. coli L6 and rat L9 ribosomal proteins","RPL9B","YNL067w","YNL067W",null,null,0.018537056,2.29,0.031676237,2.05]
["8062_at","---","---","snR8","SNR8",null,null,0.008267137,2.06,0.010493306,2.03]
["5983_at","Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; has similarity to C. elegans Dpy-30","SDC1","YDR469w","YDR469W",null,null,0.009481404,2.27,0.016521795,2.03]
["8251_at","Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate","SFG1","YOR315w","YOR315W",null,null,0.038251188,1.78,0.026521455,2.02]
["6753_at","---","---","snR33","SNR33",null,null,0.021485439,1.86,0.018876411,2.02]
["11205_i_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Ap and has similarity to E. coli L22 and rat L17 ribosomal proteins","RPL17B","YJL177w","YJL177W",null,null,0.01777198,2.39,0.03636863,2.01]
["5739_at","---","---","YEL007w","YEL007W",null,null,0.01729962,2,0.021706928,1.98]
["7201_at","TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70) and stimulates the ATPase activity of SSA1, ts mutants reduce Hsp82p function while over expression suppresses the phenotypes of an HSP82 ts allele and a cpr7 deletion","CNS1","YBR155w","YBR155W",null,null,0.026529536,2.01,0.032862578,1.98]
["6895_at","Cytoplasmic RNA-binding protein that associates with translating ribosomes; involved in heme regulation of Hap1p as a component of the HMC complex, also involved in the organization of actin filaments; contains a La motif","SRO9","YCL037c","YCL037C",null,null,0.027516939,2.19,0.04484639,1.98]
["6413_at","Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)","HEM13","YDR044w","YDR044W",null,null,0.032224666,2,0.038846977,1.97]
["10091_at","---","---","YLR243w","YLR243W",null,null,0.011433553,2.08,0.015706936,1.97]
["7200_at","RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III; contacts DNA and affects transactivation","RPB5","YBR154c","YBR154C",null,null,0.011433553,2.14,0.01731492,1.97]
["11127_at","Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit; interacts directly with Arx1p; responsible for Tif6p recycling defects in absence of Rei1p","ALB1","YJL122w","YJL122W",null,null,0.024292478,2.33,0.049905967,1.97]
["10160_at","S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)","SAM1","YLR180w","YLR180W",null,null,0.04087182,1.64,0.021975106,1.96]
["4240_at","---","---","YIL161w","YIL161W",null,null,0.005866868,2.13,0.010493306,1.96]
["8967_at","Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis; localizes to both nucleolus and cytoplasm","NOP15","YNL110c","YNL110C",null,null,0.02185912,2.35,0.04702148,1.96]
["6643_at","---","---","YDL177c","YDL177C",null,null,0.013401028,2.02,0.019158732,1.95]
["7810_at","Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p","SRL4","YPL033c","YPL033C",null,null,0.013401028,2.04,0.019801047,1.95]
["8531_at","Dubious opening reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YOR012C; null mutant displays increased levels of spontaneous Rad52 foci","IRC11","YOR013w","YOR013W",null,null,0.011522481,2.11,0.01731492,1.95]
["9896_f_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Ap and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p; loss of both Rpl31p and Rpl39p confers lethality","RPL31B","YLR406c","YLR406C",null,null,0.019476412,2.08,0.030145485,1.94]
["4931_at","Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp46p (EXOSC5)","RRP46","YGR095c","YGR095C",null,null,0.01302024,1.93,0.015998434,1.93]
["9897_f_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Ap and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p; loss of both Rpl31p and Rpl39p confers lethality","RPL31B","YLR406c","YLR406C",null,null,0.007858818,2.13,0.014045474,1.93]
["11381_at","---","---","YAL065c","YAL065C",null,null,0.018709198,2.3,0.04081008,1.93]
["10634_at","Transcriptional activator related to Msn2p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression","MSN4","YKL062w","YKL062W",null,null,0.018511113,1.79,0.016174687,1.92]
["4478_at","Putative serine hydrolase that localizes to both the nucleus and cytoplasm; sequence is similar to S. cerevisiae Fsh2p and Fsh3p and the human candidate tumor suppressor OVCA2","FSH1","YHR049w","YHR049W",null,null,0.023993563,2.12,0.04081008,1.92]
["10312_at","Subunit of the RES complex, which is required for nuclear retention of unspliced pre-mRNAs; acts in the same pathway as Pml39p and Mlp1p","PML1","YLR016c","YLR016C",null,null,0.013401028,1.84,0.013854879,1.91]
["4915_at","---","---","YGR079w","YGR079W",null,null,0.019654872,2.08,0.032862578,1.91]
["8827_at","Nuclear exosome-associated RNA binding protein; involved in surveillance of pre-rRNAs and pre-mRNAs, and the degradation of cryptic non-coding RNAs (ncRNA); copurifies with ribosomes","MPP6","YNR024w","YNR024W",null,null,0.011065401,2.1,0.01731492,1.91]
["7104_at","---","---","YBR239c","YBR239C",null,null,0.019323736,1.84,0.021706928,1.89]
["6721_at","Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes protein asparagine-linked glycosylation; type I membrane protein required for incorporation of Ost3p or Ost6p into the OST complex","OST4","YDL232w","YDL232W",null,null,0.018709198,1.92,0.02401656,1.89]
["4475_at","Inositol monophosphatase, involved in biosynthesis of inositol and in phosphoinositide second messenger signaling; INM1 expression increases in the presence of inositol and decreases upon exposure to antibipolar drugs lithium and valproate","INM1","YHR046c","YHR046C",null,null,0.018114772,2.06,0.029934792,1.88]
["11255_at","Cytoplasmic protein involved in the regulation of enolase (ENO1); mRNA expression is induced by calcium shortage, copper deficiency (via Mac1p) and the presence of galactose (via Gal4p); mRNA expression is also regulated by the cell cycle","REE1","YJL217w","YJL217W",null,null,0.013853301,2.32,0.035063412,1.88]
["11006_at","Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity","CPR7","YJR032w","YJR032W",null,null,0.022549547,1.75,0.021230683,1.87]
["6853_at","Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus; member of the Sm protein family","MAK31","YCR020c-a","YCR020C-A",null,null,0.012773143,1.76,0.011678218,1.87]
["6499_at","Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition","APC11","YDL008w","YDL008W",null,null,0.013256554,2.04,0.022742556,1.87]
["4921_i_at","---","---","YGR085c","YGR085C",null,null,0.011717513,2.2,0.024643283,1.87]
["9895_i_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Ap and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p; loss of both Rpl31p and Rpl39p confers lethality","RPL31B","YLR406c","YLR406C",null,null,0.030776737,1.95,0.041911382,1.86]
["10273_at","---","---","YLR064w","YLR064W",null,null,0.016103525,1.96,0.023536323,1.86]
["7992_at","tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; nuclear protein that appears to be involved in tRNA export; also acts on U2 snRNA","PUS1","YPL212c","YPL212C",null,null,0.012435469,1.84,0.014404673,1.85]
["7240_at","Mitochondrial protein, putative inner membrane transporter with a role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; has similarity with Ymc1p","YMC2","YBR104w","YBR104W",null,null,0.013256554,1.94,0.019880466,1.85]
["10167_at","Member of the alpha/beta knot fold methyltransferase superfamily; required for maturation of 18S rRNA and for 40S ribosome production; interacts with RNA and with S-adenosylmethionine; associates with spindle/microtubules; forms homodimers","EMG1","YLR186w","YLR186W",null,null,0.022789545,2.11,0.04285832,1.85]
["7249_at","---","---","YBR113w","YBR113W",null,null,0.027013406,1.82,0.030458031,1.84]
["11306_at","---","---","YAR064w","YAR064W",null,null,0.028986571,1.91,0.03937848,1.84]
["4534_at","Putative RNA-binding protein, interacts with Mex67p, which is a component of the nuclear pore involved in nuclear mRNA export","MIP6","YHR015w","YHR015W",null,null,0.016103525,1.76,0.015706936,1.83]
["9852_at","Protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Ap and to rat L6 ribosomal protein; binds to 5.8S rRNA","RPL6B","YLR448w","YLR448W",null,null,0.018709198,1.92,0.027070807,1.83]
["10953_at","Conserved protein with deoxyribonucleoside triphosphate pyrophosphohydrolase activity, mediates exclusion of noncanonical purines from deoxyribonucleoside triphosphate pools; mutant is sensitive to the base analog 6-N-hydroxylaminopurine","HAM1","YJR069c","YJR069C",null,null,0.016222555,1.8,0.018342346,1.82]
["8646_at","Cytoplasmic tryptophanyl-tRNA synthetase, aminoacylates tryptophanyl-tRNA","WRS1","YOL097c","YOL097C",null,null,0.01777198,1.86,0.023262257,1.82]
["4467_at","Essential component of the Rix1 complex (with Rix1p and Ipi3p) that is required for processing of ITS2 sequences from 35S pre-rRNA; Rix1 complex associates with Mdn1p in pre-60S ribosomal particles","IPI1","YHR085w","YHR085W",null,null,0.011786537,2.26,0.030145485,1.82]
["7602_at","Protein of unknown function involved in destabilization of [URE3] prions; similar in sequence to Btn2p","CUR1","YPR158w","YPR158W",{"$nulls":4},0.03182385,1.81]
["10238_at","Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern","BUD20","YLR074c","YLR074C",null,null,0.015948728,2.01,0.02890364,1.8]
["10549_at","---","---","YKR032w","YKR032W",null,null,0.04145193,1.65,0.03250793,1.79]
["11035_at","---","---","YJL032w","YJL032W",null,null,0.019323736,1.93,0.031676237,1.79]
["11088_at","Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data","UTP18","YJL069c","YJL069C",null,null,0.018709198,2.17,0.04534572,1.79]
["9559_at","---","---","YMR074c","YMR074C",null,null,0.0234828,1.58,0.015361917,1.78]
["8017_at","---","---","snR5","SNR5",null,null,0.02447415,1.66,0.022130711,1.78]
["8178_at","---","---","YOR379c","YOR379C",null,null,0.016103525,1.83,0.021765023,1.78]
["6473_i_at","---","---","YDR012w","YDR012W",null,null,0.022591455,1.85,0.031676237,1.78]
["9774_at","DNA binding protein that recognizes oligo(dA).oligo(dT) tracts; Arg side chain in its N-terminal pentad Gly-Arg-Lys-Pro-Gly repeat is required for DNA-binding; not essential for viability","DAT1","YML113w","YML113W",null,null,0.025008066,1.86,0.036039323,1.78]
["9176_at","Essential nucleolar protein required for 40S ribosome biogenesis; physically and functionally interacts with Krr1p","KRI1","YNL308c","YNL308C",null,null,0.022255871,1.99,0.040854793,1.78]
["7997_at","Ferredoxin of the mitochondrial matrix required for formation of cellular iron-sulfur proteins; involved in heme A biosynthesis; homologous to human adrenodoxin","YAH1","YPL252c","YPL252C",null,null,0.02996325,1.67,0.026314104,1.77]
["7805_at","Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met32p","MET31","YPL038w","YPL038W",null,null,0.012723897,1.78,0.015582433,1.77]
["5684_at","Core Sm protein Sm B; part of heteroheptameric complex (with Smd1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm B and Sm B'","SMB1","YER029c","YER029C",null,null,0.017965833,1.84,0.024722164,1.77]
["7100_at","Mitochondrial ribosomal protein of the large subunit","MRPL27","YBR282w","YBR282W",null,null,0.011981552,1.89,0.019428419,1.77]
["11062_at","Bud tip localized protein of unknown function; mRNA is targeted to the bud by a She2p dependent transport system; mRNA is cell cycle regulated via Fkh2p, peaking in G2/M phase; null mutant displays increased levels of spontaneous Rad52p foc","IRC8","YJL051w","YJL051W",null,null,0.01777198,1.9,0.027701464,1.77]
["4223_at","N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Bp, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p","RPL16A","YIL133c","YIL133C",null,null,0.015305048,1.89,0.023893952,1.76]
["9760_at","Putative cytochrome b5 reductase, localized to the plasma membrane; may be involved in regulation of lifespan; required for maturation of Gas1p and Pho8p, proposed to be involved in protein trafficking","PGA3","YML125c","YML125C",null,null,0.027884513,1.94,0.04986039,1.75]
["5101_at","Homeodomain-containing protein and putative transcription factor found associated with chromatin; target of SBF transcription factor; induced during meiosis and under cell-damaging conditions; similar to Cup9p transcription factor","TOS8","YGL096w","YGL096W",null,null,0.033174235,1.51,0.01731492,1.74]
["7359_at","Histone H2B, core histone protein required for chromatin assembly and chromosome function; nearly identical to HTB1; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation","HTB2","YBL002w","YBL002W",null,null,0.025650209,1.67,0.024643283,1.74]
["9522_at","V-ATPase assembly factor, functions with other V-ATPase assembly factors in the ER to efficiently assemble the V-ATPase membrane sector (V0)","PKR1","YMR123w","YMR123W",null,null,0.01777198,1.72,0.019782625,1.74]
["10192_at","Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; suppressor of rna1-1 mutation; may be involved in RNA export from nucleus","SRN2","YLR119w","YLR119W",null,null,0.01777198,1.75,0.021765023,1.74]
["10531_at","Subunit of U3-containing 90S preribosome complex involved in production of 18S rRNA and assembly of small ribosomal subunit","UTP30","YKR060w","YKR060W",null,null,0.03984505,1.75,0.04658004,1.74]
["5109_at","---","---","YGL088w","YGL088W",null,null,0.042742193,1.69,0.044068515,1.73]
["10194_at","Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor","YPS3","YLR121c","YLR121C",null,null,0.019466328,1.75,0.024722164,1.73]
["10707_at","Subunit of the signal recognition particle (SRP), which functions in protein targeting to the endoplasmic reticulum membrane; not found in mammalian SRP; forms a pre-SRP structure in the nucleolus that is translocated to the cytoplasm","SRP21","YKL122c","YKL122C",null,null,0.018709198,1.79,0.026042946,1.73]
["10473_i_at","Fusion protein, identical to Rpl40Bp, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes /// Fusion protein, identical to Rpl40Ap, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes","RPL40A /// RPL40B","YKR094c","YKR094C",null,null,0.01442804,1.89,0.02530794,1.73]
["6569_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p; loss of both Rpl31p and Rpl39p confers lethality","RPL31A","YDL075w","YDL075W",null,null,0.013395333,1.93,0.025970072,1.73]
["11349_at","---","---","YAL018c","YAL018C",null,null,0.046325494,1.63,0.04081008,1.72]
["8825_at","Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation","MRPL50","YNR022c","YNR022C",null,null,0.02153654,1.67,0.02320247,1.71]
["8830_at","Putative pyridoxal kinase, a key enzyme in vitamin B6 metabolism; involved in bud-site selection; diploid mutants display a random rather than a bipolar budding pattern; similarity to yeast BUD16 and human pyridoxal kinase (PDXK)","BUD17","YNR027w","YNR027W",null,null,0.015925534,1.77,0.022278732,1.71]
["10719_at","Signal recognition particle (SRP) receptor beta subunit; involved in SRP-dependent protein targeting; anchors Srp101p to the ER membrane","SRP102","YKL154w","YKL154W",null,null,0.019722676,1.77,0.028099533,1.71]
["8270_f_at","Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Bp and has similarity to rat ribosomal protein S10","RPS10A","YOR293w","YOR293W",null,null,0.022091942,1.82,0.03598452,1.7]
["10742_at","---","---","YKL177w","YKL177W",null,null,0.019323736,1.69,0.023536323,1.69]
["4805_at","Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp41p (EXOSC4)","SKI6","YGR195w","YGR195W",null,null,0.019323736,1.79,0.03071439,1.69]
["10268_at","3'-5' RNA exonuclease; involved in 3'-end processing of U4 and U5 snRNAs, 5S and 5.8S rRNAs, and RNase P and RNase MRP RNA; localized to mitochondria and null suppresses escape of mtDNA to nucleus in yme1 yme2 mutants; RNase D exonuclease","REX2","YLR059c","YLR059C",null,null,0.048190325,1.57,0.03907704,1.68]
["9884_at","Protein that regulates the nuclear localization of ribonucleotide reductase Rnr2p and Rnr4p subunits; phosphorylated by Dun1p in response to DNA damage and degraded; N-terminal half has similarity to S. pombe Spd1 protein","DIF1","YLR437c","YLR437C",null,null,0.03654931,1.62,0.036039323,1.67]
["7539_at","RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III; part of central core; similar to bacterial omega subunit","RPO26","YPR187w","YPR187W",null,null,0.020502368,1.76,0.031676237,1.67]
["8957_at","Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs","IMP4","YNL075w","YNL075W",null,null,0.0234828,1.92,0.04994374,1.67]
["9722_at","Component of the TRAPP (transport protein particle) complex, which plays an essential role in the vesicular transport from endoplasmic reticulum to Golgi","BET5","YML077w","YML077W",null,null,0.035131406,1.65,0.038846977,1.66]
["5644_at","---","---","YER071c","YER071C",null,null,0.018300293,1.66,0.022233456,1.66]
["9646_at","---","---","YML018c","YML018C",null,null,0.023557536,1.74,0.036039323,1.66]
["10022_at","Chitin deacetylase, together with Cda2p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall","CDA1","YLR307w","YLR307W",null,null,0.017965833,1.75,0.027168555,1.66]
["8460_at","Golgi membrane protein involved in manganese homeostasis; overproduction suppresses the sod1 (copper, zinc superoxide dismutase) null mutation","ATX2","YOR079c","YOR079C",null,null,0.0234828,1.74,0.03725297,1.64]
["4119_at","Ubiquitin-like protein with weak sequence similarity to ubiquitin; depends on the E1-like activating enzyme Uba4p; molecular function of the Urm1p pathway is unknown, but it is required for normal growth, particularly at high temperature","URM1","YIL008w","YIL008W",null,null,0.019476412,1.84,0.040215775,1.64]
["11201_at","Subunit of heterohexameric prefoldin, which binds cytosolic chaperonin and transfers target proteins to it; involved in the biogenesis of actin and of alpha- and gamma-tubulin","PFD1","YJL179w","YJL179W",null,null,0.032816846,1.62,0.037576444,1.63]
["10166_at","Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Bp and to rat L37 ribosomal protein","RPL37A","YLR185w","YLR185W",null,null,0.011786537,1.92,0.029082483,1.63]
["9090_at","---","---","YNL213c","YNL213C",null,null,0.024470093,1.65,0.032862578,1.62]
["9039_at","---","---","YNL174w","YNL174W",null,null,0.03562021,1.67,0.04702148,1.62]
["6105_at","Component of the lid subcomplex of the regulatory subunit of the 26S proteasome; involved in mRNA export mediated by the TREX-2 complex (Sac3p-Thp1p); ortholog of human DSS1","SEM1","YDR363w-a","YDR363W-A",null,null,0.018114772,1.72,0.028556397,1.62]
["7922_at","Phosphopantetheine:protein transferase (PPTase), activates mitochondrial acyl carrier protein (Acp1p) by phosphopantetheinylation","PPT2","YPL148c","YPL148C",null,null,0.03692036,1.54,0.032991562,1.61]
["10717_at","Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Bp and has similarity to rat S27 ribosomal protein","RPS27A","YKL156w","YKL156W",null,null,0.021419922,1.65,0.02890364,1.61]
["4394_at","Deoxycytidine monophosphate (dCMP) deaminase required for dCTP and dTTP synthesis; expression is NOT cell cycle regulated","DCD1","YHR144c","YHR144C",null,null,0.018709198,1.71,0.03071439,1.61]
["5125_at","---","---","YGL117w","YGL117W",null,null,0.0182993,1.82,0.038048793,1.61]
["7824_at","Component of the ESCRT-I complex (Stp22p, Srn2p, Vps28p, and Mvb12p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; conserved C-terminal domain interacts with ESCRT-III subunit Vps20p","VPS28","YPL065w","YPL065W",{"$nulls":4},0.04767422,1.61]
["5568_at","---","---","YER128w","YER128W",null,null,0.03984505,1.53,0.036039323,1.6]
["4194_at","Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling","PRM5","YIL117c","YIL117C",null,null,0.02153654,1.66,0.03157696,1.6]
["4932_at","Mitochondrial membrane transporter that mediates uptake of the essential cofactor thiamine pyrophosphate (ThPP) into mitochondria; expression appears to be regulated by carbon source; member of the mitochondrial carrier family","TPC1","YGR096w","YGR096W",null,null,0.03984505,1.53,0.036039323,1.59]
["9864_at","---","---","YLR460c","YLR460C",null,null,0.026725851,1.72,0.045333907,1.59]
["10910_at","Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans","STE24","YJR117w","YJR117W",null,null,0.034512978,1.57,0.03782841,1.58]
["7761_at","Putative transcription factor; multicopy suppressor of mutations that cause low activity of the cAMP/protein kinase A pathway; highly similar to Sut1p","SUT2","YPR009w","YPR009W",null,null,0.031803627,1.61,0.041157156,1.58]
["9022_at","---","---","YNL146w","YNL146W",{"$nulls":4},0.037576444,1.58]
["8724_at","Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines","HPF1","YOL155c","YOL155C",null,null,0.04731469,1.47,0.03650932,1.57]
["10633_at","---","---","YKL063c","YKL063C",null,null,0.028378658,1.6,0.036039323,1.57]
["8946_at","---","---","YNL086w","YNL086W",null,null,0.03344852,1.6,0.041897196,1.57]
["10787_at","---","---","snR3","SNR3",null,null,0.021059485,1.62,0.029842753,1.57]
["10674_at","Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p","KTI12","YKL110c","YKL110C",null,null,0.02506155,1.65,0.03907704,1.57]
["4494_at","Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Ap and has similarity to rat S27 ribosomal protein","RPS27B","YHR021c","YHR021C",null,null,0.025606077,1.67,0.042446047,1.57]
["5044_at","Specialized J-protein that functions with Hsp70 in Fe-S cluster biogenesis in mitochondria, involved in iron metabolism; contains a J domain typical to J-type chaperones; localizes to the mitochondrial matrix","JAC1","YGL018c","YGL018C",null,null,0.018709198,1.73,0.03574261,1.57]
["10954_at","Deoxyhypusine hydroxylase, a HEAT-repeat containing metalloenzyme that catalyzes hypusine formation; binds to and is required for the modification of Hyp2p (eIF5A); complements S. pombe mmd1 mutants defective in mitochondrial positioning","LIA1","YJR070c","YJR070C",null,null,0.02184698,1.79,0.048486076,1.57]
["11196_at","Protein proposed to be involved in the modification of N-linked oligosaccharides, osmotic stress response, telomere uncapping and elongation, transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Bud32p","GON7","YJL184w","YJL184W",{"$nulls":4},0.04728336,1.57]
["8725_g_at","Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines","HPF1","YOL155c","YOL155C",{"$nulls":4},0.04865961,1.57]
["7082_at","Protein of unknown function; the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss","AIM5","YBR262c","YBR262C",null,null,0.026529536,1.57,0.032054007,1.56]
["7774_at","Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex; stimulates superhelical relaxing and ssDNA binding activities of Top3p; involved in response to DNA damage; null mutants display increased rates of recombination and delayed S phase","RMI1","YPL024w","YPL024W",null,null,0.03034784,1.58,0.038799606,1.56]
["10016_at","---","---","YLR301w","YLR301W",null,null,0.020497566,1.63,0.031132372,1.56]
["4222_at","Protein required for transport of flavin adenine dinucleotide (FAD), a synthesis product of riboflavin, across the mitochondrial membrane","FLX1","YIL134w","YIL134W",{"$nulls":4},0.04303229,1.56]
["4372_at","Subunit of the THO complex, which connects transcription elongation and mitotic recombination, and of the TREX complex, which is recruited to activated genes and couples transcription to mRNA export; involved in telomere maintenance","THP2","YHR167w","YHR167W",{"$nulls":4},0.045333907,1.56]
["7081_at","Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; has a role in protein synthesis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YBR261C is not an essential gene","TAE1","YBR261c","YBR261C",null,null,0.026400665,1.57,0.032862578,1.55]
["10650_at","Kinetochore protein with homology to human CENP-C, required for structural integrity of the spindle during anaphase spindle elongation, interacts with histones H2A, H2B, and H4, phosphorylated by Ipl1p","MIF2","YKL089w","YKL089W",null,null,0.027303405,1.65,0.04538689,1.55]
["7658_at","17-kDa component of the U4/U6aU5 tri-snRNP, plays an essential role in pre-mRNA splicing, orthologue of hDIM1, the human U5-specific 15-kDa protein","DIB1","YPR082c","YPR082C",null,null,0.03142774,1.56,0.04055224,1.53]
["7366_at","Deletion suppressor of mpt5 mutation","DSF2","YBR007c","YBR007C",null,null,0.031229533,1.59,0.042501356,1.53]
["11134_at","Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition","ASF1","YJL115w","YJL115W",null,null,0.014612608,1.73,0.033943694,1.53]
["8530_g_at","Dubious opening reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YOR012C; null mutant displays increased levels of spontaneous Rad52 foci","IRC11","YOR012w","YOR012W",null,null,0.046512563,1.44,0.03636863,1.52]
["11008_at","Protein required for assembly of cytochrome c oxidase; exists as an oligomer that is integral to the mitochondrial inner membrane and faces the intermembrane space; contains a twin Cx9C motif","PET191","YJR034w","YJR034W",null,null,0.036427666,1.53,0.042501356,1.52]
["10729_at","RNA polymerase III subunit C25, required for transcription initiation; forms a heterodimer with Rpc17p; paralog of Rpb7p","RPC25","YKL144c","YKL144C",null,null,0.025124025,1.66,0.047723863,1.52]
["6066_at","---","---","YDR415c","YDR415C",{"$nulls":4},0.04865961,1.52]
["9529_at","---","---","YMR130w","YMR130W",null,null,0.04824951,1.46,0.044123042,1.51]
["4185_at","Zinc knuckle protein, involved in nuclear RNA quality control as a component of the TRAMP complex; stimulates the poly(A) polymerase activity of Pap2p in vitro; functionally redundant with Air2p","AIR1","YIL079c","YIL079C",null,null,0.03142774,1.58,0.04702148,1.51]
["10709_at","Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, thiosulfate, and isopropylmalate; member of the mitochondrial carrier family","OAC1","YKL120w","YKL120W",null,null,0.025931628,1.62,0.044468347,1.51]
["10301_at","Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Ap; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal","RPS0B","YLR048w","YLR048W",null,null,0.026725851,1.62,0.04728336,1.51]
["7564_at","Mitochondrial ribosomal protein of the small subunit","MRP2","YPR166c","YPR166C",{"$nulls":4},0.036084,1.51]
["5762_at","---","---","YEL028w","YEL028W",{"$nulls":4},0.04081008,1.51]
["9926_at","Covalently linked cell wall glycoprotein, present in the inner layer of the cell wall","CCW14","YLR390W-A","YLR391W-A",null,null,0.037625324,1.47,0.037576444,1.5]
["10508_at","Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis","DAD2","YKR083c","YKR083C",null,null,0.018709198,1.61,0.03368312,1.5]
["8444_at","Negative regulator of glucose-induced cAMP signaling; directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p","RGS2","YOR107w","YOR107W",null,null,0.03984505,1.47,0.04119947,1.49]
["9327_at","Phosphoglucomutase, catalyzes interconversion of glucose-1-phosphate and glucose-6-phospate; transcription induced in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; non-essential","PGM3","YMR278w","YMR278W",null,null,0.023288528,1.59,0.041897196,1.48]
["8969_at","---","---","YNL108c","YNL108C",null,null,0.033883892,1.48,0.04081008,1.47]
["10563_at","Adenylylsulfate kinase, required for sulfate assimilation and involved in methionine metabolism","MET14","YKL001c","YKL001C",null,null,0.030541996,1.5,0.040854793,1.47]
["8338_at","Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable","ISU2","YOR226c","YOR226C",{"$nulls":4},0.04794775,1.47]
["5707_at","Protein of unknown function that associates with ribosomes and has a putative RNA binding domain; interacts with Tma22p; null mutant exhibits translation defects; has homology to human oncogene MCT-1","TMA20","YER007c-a","YER007C-A",null,null,0.03054628,1.52,0.044468347,1.46]
["10052_at","Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER","SEC72","YLR292c","YLR292C",{"$nulls":4},0.04658004,1.46]
["9602_at","Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling","CSI1","YMR025w","YMR025W",{"$nulls":4},0.0472941,1.45]
["9968_s_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Bp and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA /// Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA","RPL26A /// RPL26B","YLR344w","YLR344W",null,null,0.01777198,1.64,0.04704113,1.43]
["5816_at","D-Amino acid N-acetyltransferase, catalyzes N-acetylation of D-amino acids through ordered bi-bi mechanism in which acetyl-CoA is first substrate bound and CoA is last product liberated; similar to Hpa2p, acetylates histones weakly in vitro","HPA3","YEL066w","YEL066W",null,null,0.045320865,1.41]
["10172_at","Proline oxidase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; PUT1 transcription is induced by Put3p in the presence of proline and the absence of a preferred nitrogen source","PUT1","YLR142w","YLR142W",null,null,0.04533356,1.43]
["7792_at","GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to ADP-ribosylation factor","ARL3","YPL051w","YPL051W",null,null,0.04466735,1.46]
["6901_at","Essential protein involved in rRNA processing and ribosome biogenesis","RRP7","YCL031c","YCL031C",null,null,0.03909053,1.47]
["9904_at","---","---","YLR413w","YLR413W",null,null,0.046572816,1.47]
["5683_at","Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes","MIG3","YER028c","YER028C",null,null,0.036086515,1.48]
["11074_at","Protein of unknown function with proposed role in maintenance of genome integrity; deletion mutant displays elevated rates of LOH; induced during sporulation; repressed during vegetative growth by Sum1p and Hst1p; sequence similar to IRC1","LOH1","YJL038c","YJL038C",null,null,0.03909053,1.48]
["8186_at","---","---","YOR342c","YOR342C",null,null,0.040407985,1.49]
["7814_at","Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein","GPI2","YPL076w","YPL076W",null,null,0.037625324,1.49]
["7606_at","Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing","ORC4","YPR162c","YPR162C",null,null,0.041642867,1.49]
["9684_s_at","Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Bp and has similarity to E. coli S13 and rat S18 ribosomal proteins /// Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Ap and has similarity to E. coli S13 and rat S18 ribosomal proteins","RPS18A /// RPS18B","YML026c","YML026C",null,null,0.04029388,1.5]
["8668_at","Protein component of the large (60S) ribosomal subunit, identical to Rpl18Bp and has similarity to rat L18 ribosomal protein; intron of RPL18A pre-mRNA forms stem-loop structures that are a target for Rnt1p cleavage leading to degradation","RPL18A","YOL120c","YOL120C",null,null,0.03562021,1.5]
["7708_f_at","Protein component of the large (60S) ribosomal subunit, identical to Rpl43Bp and has similarity to rat L37a ribosomal protein; null mutation confers a dominant lethal phenotype","RPL43A","YPR043w","YPR043W",null,null,0.04560451,1.5]
["5244_at","Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; mtc3 is synthetically sick with cdc13-1","MTC3","YGL226w","YGL226W",null,null,0.036086515,1.51]
["10925_at","G protein gamma subunit, forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling","STE18","YJR086w","YJR086W",null,null,0.032923836,1.51]
["10108_at","Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity","CPR6","YLR216c","YLR216C",null,null,0.040639192,1.51]
["8359_at","Imidazoleglycerol-phosphate dehydratase, catalyzes the sixth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control via Gcn4p","HIS3","YOR202w","YOR202W",null,null,0.040776793,1.51]
["4110_at","---","---","YIL014C-A","YIL015C-A",null,null,0.041143574,1.52]
["8787_at","Ubiquitin-like protein modifier, may function in modification of Sph1p and Hbt1p, functionally complemented by the human or S. pombe ortholog; mechanism of Hub1p adduct formation not yet clear","HUB1","YNR032c-a","YNR032C-A",null,null,0.03692036,1.52]
["4061_at","Subunit of the anaphase-promoting complex (APC); necessary for maintaining sister chromatid cohesion in prophase I of meiosis by inhibiting premature ubiquitination and subsequent degradation of substrates by the APC(Ama1) ubiquitin ligase","MND2","YIR025w","YIR025W",null,null,0.038212948,1.53]
["10859_at","---","---","YJR157w","YJR157W",null,null,0.047402546,1.53]
["10003_f_at","Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Ap and has similarity to rat S25 ribosomal protein","RPS25B","YLR333c","YLR333C",null,null,0.045403827,1.53]
["9692_at","Subunit of the THO complex, which is a nuclear complex comprised of Hpr1p, Mft1p, Rlr1p, and Thp2p, that is involved in transcription elongation and mitotic recombination; involved in telomere maintenance","MFT1","YML062c","YML062C",null,null,0.048937034,1.53]
["4993_at","Subunit F of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane","VMA7","YGR020c","YGR020C",null,null,0.03909053,1.54]
["4499_at","Homoserine kinase, conserved protein required for threonine biosynthesis; expression is regulated by the GCN4-mediated general amino acid control pathway","THR1","YHR025w","YHR025W",null,null,0.044708457,1.54]
["11067_at","Putative lipoate-protein ligase, required along with Lip2 and Lip5 for lipoylation of Lat1p and Kgd2p; similar to E. coli LplA; null mutant displays reduced frequency of mitochondrial genome loss","AIM22","YJL046w","YJL046W",null,null,0.03984505,1.55]
["6516_at","Mitochondrial tRNA:pseudouridine synthase, catalyzes the formation of pseudouridine at position 32 in mitochondrial tRNAs; contains an N-terminal mitochondrial targeting sequence","PUS9","YDL036c","YDL036C",null,null,0.042154554,1.56]
["10334_at","Copper metallochaperone that transfers copper to Sco1p and Cox11p for eventual delivery to cytochrome c oxidase","COX17","YLL009c","YLL009C",null,null,0.03543586,1.56]
["10351_at","Protein of unknown function, required for cell growth and possibly involved in rRNA processing; mRNA is cell cycle regulated","GRC3","YLL035w","YLL035W",null,null,0.03654931,1.56]
["10092_at","Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p","MAP1","YLR244c","YLR244C",null,null,0.043581985,1.56]
["8699_at","Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation","MED7","YOL135c","YOL135C",null,null,0.048727226,1.56]
["11159_s_at","Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Bp and has similarity to rat S21 ribosomal protein /// Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Ap and has similarity to rat S21 ribosomal protein","RPS21A /// RPS21B","YJL136c","YJL136C",null,null,0.029508695,1.59]
["11318_at","---","---","YAL004w","YAL004W",null,null,0.03984505,1.6]
["6513_at","Pheromone-regulated protein, predicted to have one transmembrane segment; promoter contains Gcn4p binding elements","PRM7","YDL039c","YDL039C",null,null,0.048190325,1.6]
["6599_at","Ribosomal protein P1 beta, component of the ribosomal stalk, which is involved in interaction of translational elongation factors with ribosome; accumulation is regulated by phosphorylation and interaction with the P2 stalk component","RPP1B","YDL130w","YDL130W",null,null,0.026725851,1.6]
["6707_at","Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA","TRM8","YDL201w","YDL201W",null,null,0.04087182,1.6]
["5060_at","Catalytic component of UDP-GlcNAc transferase, required for the second step of dolichyl-linked oligosaccharide synthesis; anchored to the ER membrane via interaction with Alg14p; similar to bacterial and human glycosyltransferases","ALG13","YGL047w","YGL047W",null,null,0.03147437,1.6]
["4815_at","---","---","YGR205w","YGR205W",null,null,0.033883892,1.6]
["4780_at","Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Bp; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal","RPS0A","YGR214w","YGR214W",null,null,0.048730426,1.6]
["9318_at","---","---","YMR310c","YMR310C",null,null,0.035909276,1.6]
["7785_at","Mitochondrial ribosomal protein of the small subunit","MRPS16","YPL013c","YPL013C",null,null,0.042154554,1.6]
["6672_s_at","Protein component of the large (60S) ribosomal subunit, identical to Rpl35Bp and has similarity to rat L35 ribosomal protein /// Protein component of the large (60S) ribosomal subunit, identical to Rpl35Ap and has similarity to rat L35 ribosomal protein","RPL35A /// RPL35B","YDL191w","YDL191W",null,null,0.035131406,1.61]
["5670_i_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Bp and has similarity to rat L34 ribosomal protein /// Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Ap and has similarity to rat L34 ribosomal protein","RPL34A /// RPL34B","YER056c-a","YER056C-A",null,null,0.049670164,1.61]
["8823_at","Putative metalloprotease of the mitochondrial inner membrane, required for processing of Atp6p; has an additional role in assembly of the F0 sector of the F1F0 ATP synthase complex","ATP23","YNR020c","YNR020C",null,null,0.032224666,1.61]
["8253_at","---","---","YOR277c","YOR277C",null,null,0.034512978,1.61]
["4173_at","Mitochondrial ribosomal protein of the small subunit","RSM25","YIL093c","YIL093C",null,null,0.048937034,1.62]
["10714_at","Protein involved in calcineurin regulation during calcium signaling; has similarity to H. sapiens DSCR1 which is found in the Down Syndrome candidate region","RCN1","YKL159c","YKL159C",null,null,0.04533356,1.62]
["8519_at","Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family involved in mRNA export from the nucleus; involved in translation termination","DBP5","YOR046c","YOR046C",null,null,0.023993563,1.62]
["6171_at","Sphinganine C4-hydroxylase, catalyses the conversion of sphinganine to phytosphingosine in sphingolipid biosyntheis","SUR2","YDR297w","YDR297W",null,null,0.048727226,1.63]
["4201_at","Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; deletion mutant exhibits a weak vacuolar protein sorting defect, enhanced resistance to caspofungin, and is synthetically lethal with MEN mutants","MNI1","YIL110w","YIL110W",null,null,0.029339138,1.63]
["11206_f_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Ap and has similarity to E. coli L22 and rat L17 ribosomal proteins","RPL17B","YJL177w","YJL177W",null,null,0.046572816,1.63]
["8595_at","Homolog of Gpm1p phosphoglycerate mutase, which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; may be non-functional derivative of a gene duplication event","GPM3","YOL056w","YOL056W",null,null,0.03654931,1.63]
["7633_s_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Bp; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11 /// Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Ap; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11","RPL11A /// RPL11B","YPR102c","YPR102C",null,null,0.037625324,1.63]
["11376_at","Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; critical to kinetochore assembly","MTW1","YAL034w-a","YAL034W-A",null,null,0.032224666,1.64]
["10394_at","---","---","YLL037w","YLL037W",null,null,0.044330772,1.64]
["9923_f_at","Protein component of the small (40S) ribosomal subunit; nearly identical to Rps29Bp and has similarity to rat S29 and E. coli S14 ribosomal proteins","RPS29A","YLR388w","YLR388W",null,null,0.032224666,1.64]
["9414_f_at","Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Ap and has similarity to rat ribosomal protein S10","RPS10B","YMR230w","YMR230W",null,null,0.040401895,1.64]
["7383_at","S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; similar to Nop2p and human proliferation associated nucleolar protein p120","NCL1","YBL024w","YBL024W",null,null,0.032542717,1.65]
["4713_at","---","---","YGR283c","YGR283C",null,null,0.023557536,1.65]
["10739_f_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Bp and has similarity to E. coli L22 and rat L17 ribosomal proteins; copurifies with the Dam1 complex (aka DASH complex)","RPL17A","YKL180w","YKL180W",null,null,0.04523257,1.65]
["7818_at","---","---","YPL071c","YPL071C",null,null,0.032021258,1.65]
["4479_at","---","---","YHR049c-a","YHR049C-A",null,null,0.049737513,1.66]
["10784_at","---","---","snR37","SNR37",null,null,0.036565006,1.67]
["6009_at","Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA","UTP6","YDR449c","YDR449C",null,null,0.046500355,1.67]
["9981_at","---","---","YLR358c","YLR358C",null,null,0.04589018,1.67]
["6543_at","GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure","PSA1","YDL055c","YDL055C",null,null,0.045963686,1.68]
["6435_at","Protein of unknown function with high similarity to Rtr1p; exhibits genetic interactions with Rtr1p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YDR066C is not an essential gene","RTR2","YDR066c","YDR066C",null,null,0.03287093,1.68]
["8406_at","Core Sm protein Sm E; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm E","SME1","YOR159c","YOR159C",null,null,0.037277464,1.68]
["6654_at","Essential NTPase required for small ribosome subunit synthesis, mediates processing of the 20S pre-rRNA at site D in the cytoplasm but associates only transiently with 43S preribosomes via Rps14p, may be the endonuclease for site D","FAP7","YDL166c","YDL166C",null,null,0.036855374,1.69]
["10332_at","Essential protein required for biogenesis of 40S (small) ribosomal subunit; has similarity to the beta subunit of trimeric G-proteins and the splicing factor Prp4p","SOF1","YLL011w","YLL011W",null,null,0.048727226,1.69]
["9886_at","Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA","LSM3","YLR438c-a","YLR438C-A",null,null,0.02141681,1.69]
["7338_at","P-loop ATPase with similarity to human OLA1 and bacterial YchF; identified as specifically interacting with the proteasome; protein levels are induced by hydrogen peroxide","OLA1","YBR025c","YBR025C",null,null,0.035131406,1.7]
["9465_at","Calpain-like cysteine protease involved in proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans palB","RIM13","YMR154c","YMR154C",null,null,0.047018852,1.71]
["10272_at","---","---","YLR063w","YLR063W",null,null,0.025124025,1.72]
["5804_at","---","---","snR63","SNR63",null,null,0.0234828,1.73]
["10883_at","Protein involved in minichromosome maintenance; component of the kinetochore; binds to centromeric DNA in a Ctf19p-dependent manner","MCM22","YJR135c","YJR135C",null,null,0.037625324,1.73]
["8847_at","Nucleolar protein with similarity to large ribosomal subunit L7 proteins; constituent of 66S pre-ribosomal particles; plays an essential role in processing of precursors to the large ribosomal subunit RNAs","RLP7","YNL002c","YNL002C",null,null,0.03329286,1.74]
["9994_at","Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein","RPL38","YLR325c","YLR325C",null,null,0.023661098,1.75]
["9420_i_at","N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Bp and has similarity to rat L36 ribosomal protein; binds to 5.8 S rRNA","RPL36A","YMR194w","YMR194W",null,null,0.028533133,1.75]
["8259_at","---","---","YOR283w","YOR283W",null,null,0.0234828,1.75]
["6414_at","RNA polymerase III subunit C11; mediates pol III RNA cleavage activity and is important for termination of transcription; homologous to TFIIS","RPC11","YDR045c","YDR045C",null,null,0.0234828,1.76]
["10955_at","---","---","YJR071w","YJR071W",null,null,0.04560451,1.76]
["8923_at","Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine; involved in the excretion of excess amino acids","AQR1","YNL065w","YNL065W",null,null,0.041143574,1.76]
["4343_at","6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone and adaptation to oxidative stress","GND1","YHR183w","YHR183W",null,null,0.048727226,1.77]
["10325_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Bp and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA","RPL15A","YLR029c","YLR029C",null,null,0.046512563,1.78]
["4339_at","Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye3p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism","OYE2","YHR179w","YHR179W",null,null,0.035472132,1.8]
["6671_at","ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p","ARF1","YDL192w","YDL192W",null,null,0.032021258,1.81]
["6050_at","Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome","HPT1","YDR399w","YDR399W",null,null,0.03984505,1.81]
["4797_at","Nonessential protein of unknown function; predicted to be involved in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; similar to mammalian BRP16 (Brain protein 16)","HGH1","YGR187c","YGR187C",null,null,0.030397262,1.81]
["6070_s_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Bp; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins /// Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Ap; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins","RPL12A /// RPL12B","YDR418w","YDR418W",null,null,0.034620747,1.82]
["7715_at","---","---","YPR050c","YPR050C",null,null,0.045774836,1.82]
["10409_at","---","---","snR69","SNR69",null,null,0.04533356,1.84]
["7401_at","Protein involved in G2/M phase progression and response to DNA damage, interacts with Rad53p; contains an RNA recognition motif, a nuclear localization signal, and several SQ/TQ cluster domains; hyperphosphorylated in response to DNA damage","PIN4","YBL051c","YBL051C",null,null,0.046953686,1.85]
["10951_at","Protein of unknown function, essential for growth under standard (aerobic) conditions but not under anaerobic conditions","YAE1","YJR067c","YJR067C",null,null,0.034512978,1.86]
["7191_f_at","Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Ap and has similarity to E. coli S4 and rat S9 ribosomal proteins","RPS9B","YBR189w","YBR189W",null,null,0.037277464,1.87]
["11389_at","Protein of unknown function, localized in the nucleoplasm and the nucleolus, genetically interacts with MTR2 in 60S ribosomal protein subunit export","ECM1","YAL059w","YAL059W",null,null,0.03766025,1.89]
["9378_at","RNAase III; involved in rDNA transcription and rRNA processing; also cleaves a stem-loop structure at the 3' end of U2 snRNA to ensure formation of the correct U2 3' end","RNT1","YMR239c","YMR239C",null,null,0.037118897,1.9]
["6560_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Bp; not essential for viability; has similarity to rat L13 ribosomal protein","RPL13A","YDL082w","YDL082W",null,null,0.04116366,1.91]
["6186_at","Redundant rho-like GTPase Cdc42p effector; homolog of Gic1p; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region","GIC2","YDR309c","YDR309C",null,null,0.042154554,1.91]
["8728_at","Putative ferric reductase with similarity to Fre2p; expression induced by low copper levels","FRE7","YOL152w","YOL152W",null,null,0.041756816,1.91]
["5664_at","Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis","HOM3","YER052c","YER052C",null,null,0.04359523,1.92]
["5667_at","ATP phosphoribosyltransferase, a hexameric enzyme, catalyzes the first step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control","HIS1","YER055c","YER055C",null,null,0.027211513,1.95]
["4482_at","Essential protein that interacts with proteasome components and has a potential role in proteasome substrate specificity; also copurifies with 66S pre-ribosomal particles","CIC1","YHR052w","YHR052W",null,null,0.042154554,1.96]
["10386_s_at","Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Bp and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits /// Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits","RPL8A /// RPL8B","YLL045c","YLL045C",null,null,0.048190325,1.97]
["4062_at","Protein phosphatase involved in vegetative growth at low temperatures, sporulation, and glycogen accumulation; transcription induced by low temperature and nitrogen starvation; member of the dual-specificity family of protein phosphatases","YVH1","YIR026c","YIR026C",null,null,0.04347296,2]
["11203_i_at","Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Ap and has similarity to E. coli L22 and rat L17 ribosomal proteins","RPL17B","YJL177w","YJL177W",null,null,0.037467405,2.03]
["5677_at","Mitochondrial beta-keto-acyl synthase with possible role in fatty acid synthesis; required for mitochondrial respiration","CEM1","YER061c","YER061C",null,null,0.030675923,2.05]
["4851_i_at","---","---","YGR151c","YGR151C",null,null,0.04521591,2.05]
["7112_at","Protein associated with U3 and U14 snoRNAs, required for pre-rRNA processing and 40S ribosomal subunit synthesis; localized in the nucleus and concentrated in the nucleolus","ENP1","YBR247c","YBR247C",null,null,0.023557536,2.07]
["8029_at","Essential 18S rRNA dimethylase (dimethyladenosine transferase), responsible for conserved m6(2)Am6(2)A dimethylation in 3'-terminal loop of 18S rRNA, part of 90S and 40S pre-particles in nucleolus, involved in pre-ribosomal RNA processing","DIM1","YPL266w","YPL266W",null,null,0.035131406,2.07]
["10747_at","Essential protein required for the maturation of 25S rRNA and 60S ribosomal subunit assembly, localizes to the nucleolus; constituent of 66S pre-ribosomal particles","EBP2","YKL172w","YKL172W",null,null,0.034040857,2.18]
["9101_at","RNA polymerase I subunit A49","RPA49","YNL248c","YNL248C",null,null,0.029019846,2.19]
["6173_at","Essential protein that is a component of 90S preribosomes; may be involved in rRNA processing; multicopy suppressor of sensitivity to Brefeldin A; expression is induced during lag phase and also by cold shock","BFR2","YDR299w","YDR299W",null,null,0.046572816,2.21]
["7232_at","---","---","YBR141c","YBR141C",null,null,0.03692036,2.27]
["9869_at","---","---","YLR264c-a","YLR264c-a",null,null,0.011786537,2.3]
["10305_at","Essential protein with similarity to Rpl24Ap and Rpl24Bp, associated with pre-60S ribosomal subunits and required for ribosomal large subunit biogenesis","RLP24","YLR009w","YLR009W",null,null,0.03562021,2.35]
["6558_i_at","Protein component of the small (40S) ribosomal subunit; identical to Rps16Bp and has similarity to E. coli S9 and rat S16 ribosomal proteins /// Protein component of the small (40S) ribosomal subunit; identical to Rps16Ap and has similarity to E. coli S9 and rat S16 ribosomal proteins","RPS16A /// RPS16B","YDL083c","YDL083C",null,null,0.04116366,2.59]
["8621_at","Nucleolar protein, constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif","BRX1","YOL077c","YOL077C",null,null,0.027720643,2.62]
["6424_at","Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1","PST1","YDR055w","YDR055W",null,null,0.046141878,2.73]
["4447_at","Constituent of 66S pre-ribosomal particles, required for ribosomal large subunit maturation; functionally redundant with Ssf2p; member of the Brix family","SSF1","YHR066w","YHR066W",null,null,0.035131406,3.07]
["10976_at","Translation elongation factor eIF-5A, previously thought to function in translation initiation; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions","ANB1","YJR047c","YJR047C",null,null,0.019323736,3.73]
["8244_i_at","Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA","NOP58","YOR309c","YOR309C",null,null,0.044330772,3.74]
["8247_at","Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA","NOP58","YOR310c","YOR310C",null,null,0.029027011,4.05]
[]
[]
[]
[]
[]
[]
[null,"also identified as being beneficial to survival of desiccation in the phenomics analysis"]
[]
[null,"protein kinase"]
[null,"transcription factor"]