{"text_format":"2","workbook":"xls","n_sheets":3,"sheets":["Sheet1","Sheet2","Sheet3"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":0,"defined_names":0,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Sheet1","index":0,"n_rows":30,"n_cols":5,"rows_kept":30,"cut":false,"hidden":false,"merged":[[2,1,3,1],[2,4,3,4],[0,1,0,4]],"flags":["formulas_cached_only"]}
[null,"Table S2. Summary of the initial concentration values in the model."]
[]
[null,"Protein name","Value (nM) ","Value (nM) ","Reference"]
[null,null,"--- Normal","--- MDS"]
[null,"TNFa ",1.5,1.5,"Experimental Data "]
[null,"TNFR1",1,1,"Assumed"]
[null,"TNFa:TNFR1",0,0,"Assumed"]
[null,"TRAF2",1,1,"Assumed"]
[null,"TNFa:TNFR1:TRAF2",0,0,"Assumed"]
[null,"ASK1",1,1,"Assumed"]
[null,"ASK1_p",0,0,"Assumed"]
[null,"MKK3/6",1,1,"Assumed"]
[null,"MKK3/6_p",0,0,"Assumed"]
[null,"P38",4.73141,5.00251,"Experimental Data "]
[null,"P38_p",0.59108,1.18555,"Experimental Data "]
[null,"AKT",0.10247,0.03343,"Experimental Data "]
[null,"AKT_p",0.0974,0.07651,"Experimental Data "]
[null,"P53",0.08786,0.10542,"Experimental Data "]
[null,"P53_p",0,0,"Assumed"]
[null,"MEKK1",1,1,"Assumed"]
[null,"MEKK1_p",0,0,"Assumed"]
[null,"MKK4/7",1,1,"Assumed"]
[null,"MKK4/7_p",0,0,"Assumed"]
[null,"JNK",0.15233,0.1151,"Experimental Data "]
[null,"JNK_p ",0,0,"Assumed"]
[null,"C_Jun ",1,1,"Assumed"]
[null,"C_Jun_p",0.11556,0.67273,"Experimental Data "]
[null,"BCL_XL",0.155,0.15901,"Experimental Data "]
[null,"BCL_XL_p ",0,0,"Assumed"]
[null,"BCL_XL_d  (degradation)",0,0,"Assumed"]

{"sheet":"Sheet2","index":1,"n_rows":0,"n_cols":0,"rows_kept":0,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}

{"sheet":"Sheet3","index":2,"n_rows":0,"n_cols":0,"rows_kept":0,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}