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["Table S3: List of GO-terms enriched for overexpression (a,) and underexpression (b,) with CR"]
[]
["a,"]
["GO term","GO","total","overexp.","underexp.","p_overexp."]
["lipid metabolic process","GO:0006629",8255,352,216,8.006763945893719e-24]
["rhythmic process","GO:0048511",899,73,27,6.5241584933473e-19]
["monooxygenase activity","GO:0004497",2803,147,96,8.685929570169901e-18]
["circadian rhythm","GO:0007623",1025,72,45,2.1495546562843503e-15]
["detoxification of copper ion","GO:0010273",181,26,8,3.76972155053106e-13]
["retinol metabolic process","GO:0042572",298,33,5,5.45870032579381e-13]
["cellular_component","GO:0005575",219270,5771,4906,6.53798660100559e-13]
["molecular_function","GO:0003674",232675,6087,4986,4.45862077786028e-12]
["NADPH-hemoprotein reductase activity","GO:0003958",149,22,0,1.33830610996383e-11]
["microsome","GO:0005792",10612,366,316,1.57410038494143e-11]
["acyl-CoA metabolic process","GO:0006637",749,51,9,6.73249492384972e-11]
["oxidoreductase activity","GO:0016491",20263,630,469,1.2057422684638498e-10]
["nitric oxide mediated signal transduction","GO:0007263",307,30,9,1.34878702814966e-10]
["oxidation reduction","GO:0055114",19926,620,461,1.4906507397532e-10]
["acetaldehyde biosynthetic process","GO:0046186",42,12,0,2.03089271062477e-10]
["retinoic acid metabolic process","GO:0042573",456,37,11,2.2738537724523498e-10]
["extracellular region","GO:0005576",42731,1227,1102,2.50961080628729e-10]
["fatty acid metabolic process","GO:0006631",3408,143,83,3.0313211760731597e-10]
["catalytic activity","GO:0003824",28555,850,617,3.4313652092015496e-10]
["biological_process","GO:0008150",237351,6151,5091,4.41239111072727e-10]
["cellular zinc ion homeostasis","GO:0006882",306,29,10,5.55020775637077e-10]
["metabolic process","GO:0008152",22860,694,523,6.7958375971125e-10]
["tyrosine-ester sulfotransferase activity","GO:0017067",82,15,3,1.07910712854579e-09]
["nitric oxide catabolic process","GO:0046210",61,13,0,1.92300883543253e-09]
["flavin-containing monooxygenase activity","GO:0004499",132,18,1,3.4403927857842097e-09]
["amine N-methyltransferase activity","GO:0030748",33,10,4,3.48812005222381e-09]
["iron ion binding","GO:0005506",4581,175,145,3.74409556835479e-09]
["alkane 1-monooxygenase activity","GO:0018685",54,12,1,4.82303440340115e-09]
["benzaldehyde dehydrogenase (NAD+) activity","GO:0018479",91,15,4,4.8456095909029005e-09]
["retinoid metabolic process","GO:0001523",185,21,2,5.2494673050457095e-09]
["carboxylesterase activity","GO:0004091",1170,63,30,5.59922957471626e-09]
["late recombination nodule","GO:0005715",26,9,0,5.62665475964543e-09]
["2,4-dienoyl-CoA reductase (NADPH) activity","GO:0008670",61,12,0,2.09661510303469e-08]
["intrinsic to endoplasmic reticulum membrane","GO:0031227",480,34,10,3.46513918033795e-08]
["palmitoyl-CoA hydrolase activity","GO:0016290",368,29,3,3.51925578248264e-08]
["ethanol catabolic process","GO:0006068",81,13,0,7.032390139729411e-08]
["DNA photolyase activity","GO:0003913",84,13,1,1.0965034544428399e-07]
["ethanol binding","GO:0035276",118,15,2,1.7404498896161899e-07]
["negative regulation of lipoprotein lipase activity","GO:0051005",37,9,2,1.76468064103947e-07]
["MDM2 binding","GO:0070215",88,13,1,1.92422355157255e-07]
["aryl sulfotransferase activity","GO:0004062",136,16,4,2.03179596005741e-07]
["lyase activity","GO:0016829",4802,173,128,2.0422670183132998e-07]
["drug metabolic process","GO:0017144",249,22,6,2.1303717430096698e-07]
["steroid metabolic process","GO:0008202",2076,89,73,2.3286988832877797e-07]
["dodecenoyl-CoA delta-isomerase activity","GO:0004165",155,17,0,2.3847649321350295e-07]
["cholesterol 7-alpha-monooxygenase activity","GO:0008123",39,9,2,2.87861300259114e-07]
["regulation of bile acid biosynthetic process","GO:0070857",39,9,2,2.87861300259114e-07]
["positive regulation of bile acid biosynthetic process","GO:0070859",39,9,2,2.87861300259114e-07]
["cellular response to cholesterol","GO:0071397",39,9,2,2.87861300259114e-07]
["extracellular space","GO:0005615",18369,548,484,2.9128590608576297e-07]
["electron carrier activity","GO:0009055",3478,132,96,3.7860174817547495e-07]
["L-serine ammonia-lyase activity","GO:0003941",52,10,0,3.9333288248197695e-07]
["L-threonine ammonia-lyase activity","GO:0004794",52,10,0,3.9333288248197695e-07]
["aromatase activity","GO:0070330",711,41,31,4.0519831279407795e-07]
["cellular metal ion homeostasis","GO:0006875",161,17,4,4.1132022977986397e-07]
["transporter activity","GO:0005215",7159,239,192,4.779872792666699e-07]
["regulation of cholesterol metabolic process","GO:0090181",222,20,3,5.44983434618747e-07]
["peroxisome","GO:0005777",4072,149,76,5.71527383563947e-07]
["acyl-CoA thioesterase activity","GO:0016291",265,22,1,6.169508951183499e-07]
["fatty acid (omega-1)-hydroxylase activity","GO:0008393",32,8,0,6.836277385180389e-07]
["icosanoid biosynthetic process","GO:0046456",32,8,0,6.836277385180389e-07]
["behavioral response to ethanol","GO:0048149",186,18,2,6.965297650627769e-07]
["myeloid progenitor cell differentiation","GO:0002318",151,16,0,8.494000748288279e-07]
["pyridoxal phosphate binding","GO:0030170",1959,83,60,9.064436464111799e-07]
["glucose-6-phosphate transport","GO:0015760",134,15,5,9.182640196706599e-07]
["histone phosphorylation","GO:0016572",152,16,3,9.281894850886409e-07]
["oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","GO:0016712",534,33,26,1.17758923350425e-06]
["ethanol oxidation","GO:0006069",120,14,2,1.2720979005786799e-06]
["glucose-6-phosphate transmembrane transporter activity","GO:0015152",35,8,0,1.43466570984646e-06]
["negative regulation of chemokine production","GO:0032682",35,8,0,1.43466570984646e-06]
["cytosolic calcium ion transport","GO:0060401",35,8,0,1.43466570984646e-06]
["positive regulation of cardiac muscle contraction","GO:0060452",35,8,0,1.43466570984646e-06]
["extracellular matrix constituent secretion","GO:0070278",35,8,0,1.43466570984646e-06]
["positive regulation of G0 to G1 transition","GO:0070318",35,8,0,1.43466570984646e-06]
["cholesterol catabolic process","GO:0006707",176,17,2,1.43925017416105e-06]
["steroid hormone receptor activity","GO:0003707",1859,79,40,1.4520477480795798e-06]
["cellular homeostasis","GO:0019725",60,10,0,1.5742053870800699e-06]
["multicellular organismal homeostasis","GO:0048871",60,10,0,1.5742053870800699e-06]
["methionine adenosyltransferase activity","GO:0004478",123,14,0,1.7148984388897e-06]
["S-adenosylmethionine biosynthetic process","GO:0006556",123,14,0,1.7148984388897e-06]
["heme binding","GO:0020037",3600,132,111,2.14639659202236e-06]
["3-chloroallyl aldehyde dehydrogenase activity","GO:0004028",266,21,5,2.44472209524621e-06]
["ligand-dependent nuclear receptor activity","GO:0004879",1889,79,41,2.60216861199287e-06]
["nerve development","GO:0021675",204,18,3,2.63992500889557e-06]
["positive regulation of cholesterol esterification","GO:0010873",78,11,3,2.6514200847609e-06]
["thiolester hydrolase activity","GO:0016790",314,23,1,2.97355219339821e-06]
["insulin-like growth factor binding","GO:0005520",886,45,28,3.44533009765169e-06]
["symporter activity","GO:0015293",3572,130,100,3.63281497992094e-06]
["regulation of fatty acid oxidation","GO:0046320",82,11,1,4.3717714495337e-06]
["long-chain fatty acid metabolic process","GO:0001676",443,28,7,4.750331884382879e-06]
["response to glucocorticoid stimulus","GO:0051384",1021,49,16,6.08619702340139e-06]
["neurotrophin receptor binding","GO:0005165",42,8,0,6.19617508206351e-06]
["9-cis-retinoic acid metabolic process","GO:0042905",56,9,2,7.12761236437768e-06]
["alcohol dehydrogenase (NAD) activity","GO:0004022",159,15,2,7.788679486242089e-06]
["linoleic acid metabolic process","GO:0043651",87,11,1,7.835715885826129e-06]
["glycogen (starch) synthase activity","GO:0004373",57,9,1,8.28354725722035e-06]
["optic cup morphogenesis involved in camera-type eye development","GO:0002072",88,11,2,8.761010042741959e-06]
["lauric acid metabolic process","GO:0048252",46,8,2,1.25788819712481e-05]
["9-cis-retinoic acid biosynthetic process","GO:0042904",207,17,4,1.2759428469482e-05]
["carbon-carbon lyase activity","GO:0016830",60,9,1,1.27597538134363e-05]
["amino acid binding","GO:0016597",1110,51,16,1.28749833814435e-05]
["nitrate transmembrane transporter activity","GO:0015112",23,6,2,1.3453735321127499e-05]
["nitrate transport","GO:0015706",23,6,2,1.3453735321127499e-05]
["fatty acid beta-oxidation","GO:0006635",834,41,7,1.91112223154319e-05]
["carnitine O-palmitoyltransferase activity","GO:0004095",172,15,2,1.9966248642580698e-05]
["cholesterol homeostasis","GO:0042632",1160,52,22,2.04707985055137e-05]
["leg morphogenesis","GO:0035110",36,7,0,2.05585734424727e-05]
["retinol dehydrogenase activity","GO:0004745",330,22,0,2.0920964466599598e-05]
["growth factor activity","GO:0008083",4826,162,112,2.1648533285021e-05]
["water transport","GO:0006833",508,29,22,2.19711348531657e-05]
["positive regulation of lipid metabolic process","GO:0045834",65,9,2,2.47766510651816e-05]
["protein homotetramerization","GO:0051289",1146,51,23,2.9349360989110098e-05]
["15-hydroxyprostaglandin dehydrogenase (NADP+) activity","GO:0047021",38,7,0,2.98047006698569e-05]
["prostaglandin-E2 9-reductase activity","GO:0050221",38,7,0,2.98047006698569e-05]
["water channel activity","GO:0015250",363,23,19,3.05852183311517e-05]
["ectoplasm","GO:0043265",27,6,0,3.63333327895029e-05]
["progesterone receptor signaling pathway","GO:0050847",85,10,1,3.79372758186151e-05]
["lactosylceramide alpha-2,3-sialyltransferase activity","GO:0047291",41,7,1,4.9861002314505096e-05]
["regulation of cell growth","GO:0001558",1295,55,38,5.13437827521412e-05]
["brown fat cell differentiation","GO:0050873",1236,53,34,5.43627653048977e-05]
["succinate transmembrane transporter activity","GO:0015141",107,11,4,5.59796292344303e-05]
["succinate transport","GO:0015744",107,11,4,5.59796292344303e-05]
["NADP or NADPH binding","GO:0050661",1152,50,21,6.44424146118106e-05]
["neutrophil homeostasis","GO:0001780",75,9,1,7.85323216799098e-05]
["drug binding","GO:0008144",1877,72,41,0.00010253784371025201]
["arachidonic acid monooxygenase activity","GO:0008391",96,10,2,0.000107772455705779]
["cytoplasmic sequestering of NF-kappaB","GO:0007253",97,10,0,0.00011759012585490101]
["phosphatidate phosphatase activity","GO:0008195",373,22,11,0.00012685259802663]
["male germ-line stem cell division","GO:0048133",63,8,0,0.00013012342442364402]
["endocrine pancreas development","GO:0031018",429,24,9,0.000143973495217843]
["polysaccharide binding","GO:0030247",430,24,21,0.00014905549338188902]
["arachidonic acid metabolic process","GO:0019369",352,21,12,0.000152407664530651]
["protein homooligomerization","GO:0051260",2177,80,50,0.000171703320134769]
["negative regulation of astrocyte differentiation","GO:0048712",208,15,10,0.000173183261668116]
["amine sulfotransferase activity","GO:0047685",23,5,1,0.00018532847310730302]
["positive regulation of adiponectin secretion","GO:0070165",13,4,0,0.00019823592811152202]
["nicotinic acid receptor activity","GO:0070553",13,4,0,0.00019823592811152202]
["3-hydroxyacyl-CoA dehydrogenase activity","GO:0003857",308,19,1,0.00020093711756209002]
["interleukin-6-mediated signaling pathway","GO:0070102",124,11,3,0.00021097400467033002]
["response to steroid hormone stimulus","GO:0048545",496,26,14,0.000218353793704754]
["sulfate assimilation","GO:0000103",168,13,5,0.00023084598469742403]
["4-nitrophenol metabolic process","GO:0018960",37,6,0,0.00023243850863258203]
["3'-phosphoadenosine 5'-phosphosulfate binding","GO:0050656",37,6,0,0.00023243850863258203]
["sulfation","GO:0051923",37,6,0,0.00023243850863258203]
["pancreatic ribonuclease activity","GO:0004522",214,15,1,0.00023569599186176903]
["positive regulation of collagen biosynthetic process","GO:0032967",193,14,5,0.000264291157535765]
["short-chain fatty acid metabolic process","GO:0046459",53,7,2,0.000266083745866027]
["inductive cell-cell signaling","GO:0031129",25,5,0,0.000281180715313258]
["nucleolar fragmentation","GO:0007576",54,7,0,0.00029941168400769204]
["glutathione transferase activity","GO:0004364",890,39,17,0.000314543971331205]
["cellular amino acid metabolic process","GO:0006520",741,34,15,0.00032684650567540904]
["enoyl-CoA hydratase activity","GO:0004300",245,16,1,0.00032980845170097904]
["glucose homeostasis","GO:0042593",1562,60,42,0.000348458405057769]
["negative regulation of epidermal growth factor receptor activity","GO:0007175",56,7,0,0.00037609916666606004]
["response to testosterone stimulus","GO:0033574",178,13,1,0.00040386030289792503]
["lipid catabolic process","GO:0016042",2862,98,78,0.00041190142399832]
["detection of mechanical stimulus involved in equilibrioception","GO:0050973",57,7,1,0.00041992620954118805]
["nerve growth factor binding","GO:0048406",75,8,1,0.000439866453207216]
["regulation of insulin secretion","GO:0050796",607,29,27,0.000454450394759963]
["sodium ion transport","GO:0006814",3788,124,94,0.000459444424722036]
["thiosulfate transmembrane transporter activity","GO:0015117",58,7,2,0.00046773550797057304]
["malate transmembrane transporter activity","GO:0015140",58,7,2,0.00046773550797057304]
["secondary active transmembrane transporter activity","GO:0015291",58,7,2,0.00046773550797057304]
["thiosulfate transport","GO:0015709",58,7,2,0.00046773550797057304]
["malate transport","GO:0015743",58,7,2,0.00046773550797057304]
["urea transport","GO:0015840",181,13,3,0.00047348448447134806]
["cholesterol esterification","GO:0034435",42,6,3,0.000473549880924071]
["proline racemase activity","GO:0018112",28,5,0,0.0004899663026447101]
["endosomal lumen acidification","GO:0048388",59,7,0,0.00051978332787471]
["mitochondrial inner membrane","GO:0005743",12407,355,162,0.000542087611725058]
["FMN binding","GO:0010181",388,21,11,0.000553595815252124]
["ligand-regulated transcription factor activity","GO:0003706",97,9,4,0.000558338709255048]
["negative regulation of thymocyte apoptosis","GO:0070244",78,8,2,0.0005738527131804581]
["aconitate hydratase activity","GO:0003994",118,10,1,0.000579420118345473]
["glycerol transport","GO:0015793",118,10,3,0.000579420118345473]
["ammonia assimilation cycle","GO:0019676",98,9,0,0.0006018406818462921]
["aldehyde dehydrogenase (NAD) activity","GO:0004029",446,23,8,0.0006063278336585871]
["sensory perception of chemical stimulus","GO:0007606",163,12,11,0.000618017692426962]
["response to muscle activity","GO:0014850",119,10,1,0.000619124694449635]
["positive regulation of fatty acid beta-oxidation","GO:0032000",141,11,2,0.0006343514231584711]
["nucleotide-binding oligomerization domain containing 1 signaling pathway","GO:0070427",80,8,0,0.00068019610576155]
["photoreceptor outer segment","GO:0001750",928,39,17,0.0006925165426377999]
["response to stress","GO:0006950",4085,131,113,0.000707302945571501]
["NF-kappaB binding","GO:0051059",214,14,2,0.000741300766184582]
["chaperone-mediated protein folding","GO:0061077",64,7,1,0.000853187626321298]
["negative regulation of B cell apoptosis","GO:0002903",65,7,2,0.0009365399656602931]
["photoreceptor activity","GO:0009881",324,18,6,0.000984982492771707]
[]
["b,"]
["GO term","GO","total","overexp.","underep.","p_underexp"]
["sterol biosynthetic process","GO:0016126",1091,29,59,5.573036571542539e-10]
["plasma membrane","GO:0005886",68511,1690,1722,6.13637446572674e-09]
["beta-alanine transmembrane transporter activity","GO:0001761",60,1,12,6.320714703565359e-09]
["beta-alanine transport","GO:0001762",60,1,12,6.320714703565359e-09]
["taurine transmembrane transporter activity","GO:0005368",60,1,12,6.320714703565359e-09]
["taurine:sodium symporter activity","GO:0005369",60,1,12,6.320714703565359e-09]
["taurine transport","GO:0015734",60,1,12,6.320714703565359e-09]
["taurine binding","GO:0030977",60,1,12,6.320714703565359e-09]
["cholesterol biosynthetic process","GO:0006695",1022,31,53,1.5888021977569e-08]
["innate immune response","GO:0045087",3356,85,125,1.80427333270111e-08]
["response to sterol depletion","GO:0006991",68,3,12,2.7970959270318402e-08]
["steroid biosynthetic process","GO:0006694",2298,65,93,2.9691788558302402e-08]
["extracellular region","GO:0005576",42731,1227,1102,3.8365911701646805e-08]
["microsome","GO:0005792",10612,366,316,7.15154283704449e-08]
["7-dehydrocholesterol reductase activity","GO:0047598",49,0,10,9.43343142331666e-08]
["response to virus","GO:0009615",1706,46,73,1.0562829340119e-07]
["positive regulation of transcription via sterol regulatory element binding","GO:0035104",92,2,13,1.1657988277085498e-07]
["pheromone binding","GO:0005550",164,9,17,1.51747042037534e-07]
["ISG15-protein conjugation","GO:0032020",132,2,15,2.4234961561414196e-07]
["lipid biosynthetic process","GO:0008610",4030,121,139,2.49619932240764e-07]
["collagen fibril organization","GO:0030199",856,24,44,3.10935667896704e-07]
["regulation of heart rate by chemical signal","GO:0003062",60,1,10,6.95135120065985e-07]
["sterol response element binding","GO:0032810",60,1,10,6.95135120065985e-07]
["glucose 6-phosphate metabolic process","GO:0051156",250,12,20,8.758514769850559e-07]
["positive regulation of glycolysis","GO:0045821",148,3,15,1.06575719099385e-06]
["3-beta-hydroxy-delta5-steroid dehydrogenase activity","GO:0003854",283,7,21,1.5930316333933599e-06]
["fatty acid biosynthetic process","GO:0006633",2216,72,84,1.7363782531645298e-06]
["citrate metabolic process","GO:0006101",309,8,22,1.8047677119693199e-06]
["cell cortex part","GO:0044448",41,1,8,2.6251991567956597e-06]
["detection of glucose","GO:0051594",41,1,8,2.6251991567956597e-06]
["endoplasmic reticulum","GO:0005783",30121,749,778,2.6365130293585798e-06]
["antigen processing and presentation","GO:0019882",1004,10,46,3.7743052566323398e-06]
["complement activation, classical pathway","GO:0006958",853,15,41,3.95713939696462e-06]
["cellular response to mycophenolic acid","GO:0071506",74,0,10,5.01492158034443e-06]
["negative regulation of steroid biosynthetic process","GO:0010894",110,5,12,5.78800003314838e-06]
["creatine metabolic process","GO:0006600",133,0,13,8.119409686982001e-06]
["creatinine metabolic process","GO:0046449",133,0,13,8.119409686982001e-06]
["positive regulation of cholesterol biosynthetic process","GO:0045542",197,5,16,8.60369150968729e-06]
["modification-dependent protein catabolic process","GO:0019941",97,1,11,9.662599962917429e-06]
["sugar binding","GO:0005529",5415,112,167,1.19377309479655e-05]
["iron ion binding","GO:0005506",4581,175,145,1.24312633441482e-05]
["circadian rhythm","GO:0007623",1025,72,45,1.36710016288585e-05]
["cholesterol metabolic process","GO:0008203",2037,69,75,1.5599750550527298e-05]
["20-alpha-hydroxysteroid dehydrogenase activity","GO:0047006",68,1,9,1.75994838817471e-05]
["allantoin metabolic process","GO:0000255",144,1,13,1.91598859914681e-05]
["glucokinase activity","GO:0004340",86,1,10,1.94853405853609e-05]
["activation of signaling protein activity involved in unfolded protein response","GO:0006987",69,0,9,1.98461982792293e-05]
["FasL biosynthetic process","GO:0045210",39,1,7,1.99086111403877e-05]
["monooxygenase activity","GO:0004497",2803,147,96,2.0186726344938002e-05]
["syndecan binding","GO:0045545",105,3,11,2.06311192226472e-05]
["immune response","GO:0006955",4261,110,135,2.29157215802917e-05]
["defense response to virus","GO:0051607",451,11,25,2.94037349922726e-05]
["extracellular space","GO:0005615",18369,548,484,3.1100805859031005e-05]
["positive regulation of fatty acid biosynthetic process","GO:0045723",177,8,14,4.10330221214448e-05]
["positive regulation of triglyceride biosynthetic process","GO:0010867",201,3,15,4.35026032849339e-05]
["choline binding","GO:0033265",156,10,13,4.4503516873703e-05]
["glucose binding","GO:0005536",464,17,25,4.65299102855956e-05]
["cytokine receptor activity","GO:0004896",1148,30,47,4.9420185703761496e-05]
["selenocysteine lyase activity","GO:0009000",31,1,6,5.0343913742406496e-05]
["positive regulation of histone deacetylation","GO:0031065",204,5,15,5.15297401549277e-05]
["steroid delta-isomerase activity","GO:0004769",117,3,11,5.65710415094964e-05]
["regulation of transforming growth factor beta receptor signaling pathway","GO:0017015",232,4,16,6.34707248819841e-05]
["carbohydrate phosphorylation","GO:0046835",283,11,18,6.56106309430851e-05]
["collagen biosynthetic process","GO:0032964",63,4,8,6.9434597846245e-05]
["collagen","GO:0005581",626,16,30,7.52284859229385e-05]
["steroid metabolic process","GO:0008202",2076,89,73,8.26010484790896e-05]
["extracellular matrix","GO:0031012",3665,104,116,8.36823798318017e-05]
["growth hormone receptor activity","GO:0004903",65,0,8,8.70585391392265e-05]
["growth hormone receptor signaling pathway","GO:0060396",65,0,8,8.70585391392265e-05]
["cranial suture morphogenesis","GO:0060363",192,5,14,9.87063995588716e-05]
["isoleucine metabolic process","GO:0006549",195,2,14,0.00011631188845944301]
["naphthalene metabolic process","GO:0018931",37,0,6,0.00014208273683024902]
["trichloroethylene metabolic process","GO:0018979",37,0,6,0.00014208273683024902]
["acetyl-CoA biosynthetic process","GO:0006085",175,9,13,0.00014326549284741002]
["positive regulation of programmed cell death","GO:0043068",152,4,12,0.00014418968383976902]
["C-5 sterol desaturase activity","GO:0000248",38,0,6,0.000165601240187855]
["cholesterol biosynthetic process via lathosterol","GO:0033490",38,0,6,0.000165601240187855]
["lathosterol oxidase activity","GO:0050046",38,0,6,0.000165601240187855]
["oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","GO:0016712",534,33,26,0.000169657545575741]
["NADP biosynthetic process","GO:0006741",54,2,7,0.00017219991791802801]
["integral to membrane","GO:0016021",133096,3156,3104,0.00017818720572242302]
["protein disulfide isomerase activity","GO:0003756",335,3,19,0.000186790398002253]
["positive regulation of homocysteine metabolic process","GO:0050668",55,2,7,0.000193595596701822]
["proteinaceous extracellular matrix","GO:0005578",8619,238,239,0.000193719189809434]
["defense response to Gram-positive bacterium","GO:0050830",1018,24,41,0.00019906454942616902]
["calcium ion transport","GO:0006816",3675,94,114,0.00020259093465097301]
["regulation of angiogenesis","GO:0045765",423,8,22,0.00020961875151236803]
["misfolded protein binding","GO:0051787",183,2,13,0.000222669973380315]
["cellular response to glucose starvation","GO:0042149",137,2,11,0.00023204300554088]
["membrane","GO:0016020",176738,4222,4083,0.00023498337428536103]
["second-messenger-mediated signaling","GO:0019932",75,2,8,0.00023992008596426502]
["endoplasmic reticulum lumen","GO:0005788",1061,25,42,0.00024012487996708502]
["basement membrane","GO:0005604",2976,76,95,0.000256151689074293]
["NADPH oxidase complex","GO:0043020",188,1,13,0.000289383163518323]
["protein secretion","GO:0009306",239,2,15,0.00029494886482385604]
["purinergic nucleotide receptor activity, G-protein coupled","GO:0045028",376,7,20,0.000297247143419504]
["heme binding","GO:0020037",3600,132,111,0.000300480513102956]
["collagen type III","GO:0005586",59,1,7,0.00030164343787442903]
["aromatase activity","GO:0070330",711,41,31,0.000302469403913961]
["oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water","GO:0016717",240,13,15,0.000308315392226099]
["integral to plasma membrane","GO:0005887",10052,278,272,0.00032622091598320704]
["catechol O-methyltransferase activity","GO:0016206",60,2,7,0.00033506247534408404]
["phosphoinositide 3-kinase cascade","GO:0014065",79,3,8,0.000343497086946939]
["negative regulation of epinephrine secretion","GO:0032811",121,3,10,0.00034916806403108904]
["nickel ion binding","GO:0016151",168,1,12,0.00036375977190111904]
["epinephrine secretion","GO:0048242",62,2,7,0.00041078379164030205]
["hexokinase activity","GO:0004396",171,3,12,0.00042683032621530504]
["polyspecific organic cation transmembrane transporter activity","GO:0015354",82,0,8,0.000442956826167675]
["positive regulation of activated T cell proliferation","GO:0042104",303,3,17,0.00044709729864991305]
["mRNA modification","GO:0016556",331,5,18,0.00044749563660342304]
["response to ethanol","GO:0045471",1337,42,49,0.00044950637493075204]
["mitotic cell cycle G2/M transition DNA damage checkpoint","GO:0007095",172,2,12,0.000449801904010062]
["organic cation transmembrane transporter activity","GO:0015101",125,1,10,0.00045251296982939704]
["cellular response to interferon-alpha","GO:0035457",63,2,7,0.000453452440864559]
["fructose 2,6-bisphosphate metabolic process","GO:0006003",223,11,14,0.00046027744882425005]
["JAK-STAT cascade","GO:0007259",795,12,33,0.00046747259583692003]
["cell adhesion","GO:0007155",14943,360,388,0.00047311331399702103]
["taurine metabolic process","GO:0019530",277,12,16,0.000473519495097472]
["negative regulation of cell-matrix adhesion","GO:0001953",149,10,11,0.00047677997314334405]
["leukemia inhibitory factor receptor activity","GO:0004923",46,0,6,0.00048404118426469605]
["establishment or maintenance of transmembrane electrochemical gradient","GO:0010248",46,0,6,0.00048404118426469605]
["epinephrine transport","GO:0048241",46,0,6,0.00048404118426469605]
["water channel activity","GO:0015250",363,23,19,0.00050404342918891]
["regulation of insulin secretion","GO:0050796",607,29,27,0.00052598729998733]
["proton-dependent oligopeptide secondary active transmembrane transporter activity","GO:0005427",47,0,6,0.0005446513259083811]
["cerebellar Purkinje cell layer development","GO:0021680",281,2,16,0.000552782202424106]
["5-aminolevulinate synthase activity","GO:0003870",106,6,9,0.000558440147655697]
["protein import into nucleus, translocation","GO:0000060",310,14,17,0.000577830002193035]
["cholinesterase activity","GO:0004104",107,8,9,0.000597996687104157]
["substrate-bound cell migration","GO:0006929",66,0,7,0.0006030188221838771]
["polysaccharide binding","GO:0030247",430,24,21,0.0006504495465899541]
["positive regulation of natural killer cell proliferation","GO:0032819",33,0,5,0.0007125535988684041]
["response to interleukin-15","GO:0070672",33,0,5,0.0007125535988684041]
["left-handed Z-DNA binding","GO:0003692",68,0,7,0.000722759611837694]
["elevation of cytosolic calcium ion concentration","GO:0007204",2698,73,85,0.000754077886120599]
["osteoblast differentiation","GO:0001649",1264,26,46,0.000755114924965549]
["dopamine transport","GO:0015872",158,2,11,0.0007778296368880081]
["dopamine transmembrane transporter activity","GO:0005329",111,2,9,0.000779811240084193]
["cytolysis","GO:0019835",721,24,30,0.0007883257701269171]
["regulation of neuron differentiation","GO:0045664",529,10,24,0.00079116514564096]
["cyclin binding","GO:0030332",263,6,15,0.000795893182522868]
["chemokine activity","GO:0008009",1024,31,39,0.000799513252597618]
["negative regulation of female receptivity","GO:0007621",184,6,12,0.0008171025488221141]
["female pregnancy","GO:0007565",531,14,24,0.0008328311389911]
["positive regulation of prostaglandin biosynthetic process","GO:0031394",266,5,15,0.000892337707452495]
["membrane attack complex","GO:0005579",137,3,10,0.0009247618048867191]
["phosphatidylcholine biosynthetic process","GO:0006656",353,9,18,0.0009379073368875901]
["regulation of natriuresis","GO:0003078",35,1,5,0.000939991530812544]
["V1B vasopressin receptor binding","GO:0031895",35,1,5,0.000939991530812544]
["multicellular organismal water homeostasis","GO:0050891",35,1,5,0.000939991530812544]
["acyl carrier activity","GO:0000036",114,2,9,0.000943772358364513]
["organic cation transport","GO:0015695",138,1,10,0.000977696760972665]
["blood vessel development","GO:0001568",2009,43,66,0.0009977140780694932]