{"text_format":"2","workbook":"xls","n_sheets":2,"sheets":["reaction","gene"],"not_rendered":{"charts":0,"images":0,"macros":1,"external_links":1,"defined_names":1,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"reaction","index":0,"n_rows":77,"n_cols":8,"rows_kept":77,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["new reactions in iBsu1147",{"$nulls":5},"removed reactions from iBsu1103"]
["reactions","subsystem","related genes","comment",null,null,"reactions","comment"]
["R00026","Carbohydrates","BSU05840;BSU03410;BSU39260","reaction with chiral compound",null,null,"rxn00222","replaced by reaction with different chirality compounds"]
["R00357","Amino Acids and Derivatives","BSU27870","from KEGG",null,null,"rxn00299","replaced by un-lumped reactions"]
["R00428","Cofactors, Vitamins, Prosthetic Groups, Pigments","BSU22780;BSU03340","un-lump reaction",null,null,"rxn00604","replaced by reaction with different chirality compounds"]
["R00899","Amino Acids and Derivatives","BSU32050","from Uniport",null,null,"rxn00612","replaced by reaction with different cofactor"]
["R01148","Amino Acids and Derivatives","BSU09670","from Uniport",null,null,"rxn00616","replaced by reaction with different cofactor"]
["R01582","Amino Acids and Derivatives","BSU09670","from Uniport",null,null,"rxn00973","replaced by un-lumped reactions"]
["R01600","Carbohydrates","BSU24850","from KEGG",null,null,"rxn01013","replaced by reaction with different cofactor"]
["R01878","Nucleosides and Nucleotides","BSU25300","from KEGG",null,null,"rxn01109","replaced by reaction with different cofactor"]
["R02630","Carbohydrates","BSU12010","from KEGG",null,null,"rxn01281","replaced by reaction with different cofactor"]
["R02736","Carbohydrates","BSU23850","reaction with chiral compound",null,null,"rxn03406","updata of KEGG,replaced by R00253"]
["R02777","Cell Wall and Capsule","BSU37820","from Uniport",null,null,"rxn03407","isolated reaction"]
["R02918","Aminoacyl-tRNA biosynthesis","BSU29670;BSU38460","from Uniport",null,null,"rxn03409","updata of KEGG,replaced by R00253"]
["R03038","Aminoacyl-tRNA biosynthesis","BSU27410","from KEGG",null,null,"rxn08764","updata of KEGG,replaced by R05068"]
["R03646","Aminoacyl-tRNA biosynthesis","BSU37330","from KEGG"]
["R03648","Aminoacyl-tRNA biosynthesis","BSU22360","from KEGG"]
["R03650","Aminoacyl-tRNA biosynthesis","BSU00940","from KEGG"]
["R03651","Aminoacyl-tRNA biosynthesis","BSU00920","from KEGG"]
["R03654","Aminoacyl-tRNA biosynthesis","BSU25260;BSU25270","from KEGG"]
["R03655","Aminoacyl-tRNA biosynthesis","BSU27560","from KEGG"]
["R03656","Aminoacyl-tRNA biosynthesis","BSU15430","from KEGG"]
["R03657","Amino Acids and Derivatives","BSU30320","from KEGG"]
["R03658","Aminoacyl-tRNA biosynthesis","BSU00820","from KEGG"]
["R03659","Aminoacyl-tRNA biosynthesis","BSU00380","from KEGG"]
["R03660","Aminoacyl-tRNA biosynthesis","BSU28630;BSU28640","from KEGG"]
["R03661","Aminoacyl-tRNA biosynthesis","BSU16570","from KEGG"]
["R03662","Aminoacyl-tRNA biosynthesis","BSU00130","from KEGG"]
["R03663","Aminoacyl-tRNA biosynthesis","BSU28950;BSU37560","from KEGG"]
["R03664","Aminoacyl-tRNA biosynthesis","BSU11420","from KEGG"]
["R03665","Aminoacyl-tRNA biosynthesis","BSU28090","from KEGG"]
["R03905","Aminoacyl-tRNA biosynthesis","BSU06670;BSU06680;BSU06690","from KEGG"]
["R04212","Aminoacyl-tRNA biosynthesis","BSU06670;BSU06680;BSU06690","from KEGG"]
["R04286","Cofactors, Vitamins, Prosthetic Groups, Pigments","BSU13730","from Uniport"]
["R04405","Amino Acids and Derivatives","BSU13180","from KEGG"]
["R04639","Cofactors, Vitamins, Prosthetic Groups, Pigments","BSU22780;BSU03340","un-lump reaction"]
["R04773","Amino Acids and Derivatives","BSU00380","from KEGG"]
["R04951","Amino Acids and Derivatives","BSU32050","from Uniport"]
["R05046","Cofactors, Vitamins, Prosthetic Groups, Pigments","BSU22780;BSU03340","un-lump reaction"]
["R05048","Cofactors, Vitamins, Prosthetic Groups, Pigments","BSU22780;BSU03340","un-lump reaction"]
["R05053","Amino Acids and Derivatives","BSU09670","from Uniport"]
["R05577","Aminoacyl-tRNA biosynthesis","BSU27550","from KEGG"]
["R05578","Aminoacyl-tRNA biosynthesis","BSU00920","from KEGG"]
["R06514","Cell Wall and Capsule","BSU37810","from Uniport"]
["R06601","Nucleosides and Nucleotides","BSU32460","from Uniport"]
["R07460","Amino Acids and Derivatives","BSU27510;BSU27880;BSU29590","from Uniport"]
["R08218","Aminoacyl-tRNA biosynthesis","BSU00130","from KEGG"]
["R08871","Amino Acids and Derivatives","BSU36560","from Uniport"]
["R08938","Amino Acids and Derivatives","BSU36560","from Uniport"]
["R01623","Cofactors, Vitamins, Prosthetic Groups, Pigments",null,"from KEGG"]
["T00001","Membrane Transport","transport of L-Phenylalanine","Data from Biolog phenotyping arrays"]
["T00245","Membrane Transport","transport of L-Tartaric acid","Data from Biolog phenotyping arrays"]
["T00246","Membrane Transport","transport of Putrescine","Data from Biolog phenotyping arrays"]
["T00247","Membrane Transport","transport of Stachyose","Data from Biolog phenotyping arrays"]
["T00248","Membrane Transport","transport of Butanoate","Data from Biolog phenotyping arrays"]
["T00249","Membrane Transport","transport of 2-Deoxy-5-keto-D-gluconic acid","Data from Biolog phenotyping arrays"]
["R02949","Carbohydrates",null,"PMID:22361854"]
["T00003","Carbohydrates",null,"PMID:22361854"]
["T00250","Membrane Transport","transport of meso-2,3-butanediol","Data from Biolog phenotyping arrays"]
["T00251","Membrane Transport","transport of Acetoin","Data from Biolog phenotyping arrays"]
["T00252","Membrane Transport","transport of (S)-acetoin","Data from Biolog phenotyping arrays"]
["T00253","Membrane Transport","transport of D-chiro-Inositol","PMID:20133360"]
["T00254","Membrane Transport","transport of Scyllo-inositol","PMID:20133360"]
["T00004","Carbohydrates",null,"PMID:21533914"]
["T00005","Carbohydrates",null,"PMID:21533914"]
["T00006","Carbohydrates",null,"PMID:21533914"]
["E00244","[e] : C00079 <==>","exchange of L-Phenylalanine"]
["E00245","[e] : C00898 <==>","exchange of L-Tartaric acid"]
["E00246","[e] : C00134 <==>","exchange of Putrescine"]
["E00247","[e] : C01613 <==>","exchange of Stachyose"]
["E00248","[e] : C00246 <==>","exchange of Butanoate"]
["E00249","[e] : C06892 <==>","exchange of 2-Deoxy-5-keto-D-gluconic acid"]
["E00250","[e] : cpd16500 <==>","exchange of meso-2,3-butanediol"]
["E00251","[e] : C00810 <==>","exchange of Acetoin"]
["E00252","[e] : C01769 <==>","exchange of (S)-acetoin"]
["E00253","[e] : C19891 <==>","exchange of D-chiro-Inositol"]
["E00254","[e] : C06153 <==>","exchange of Scyllo-inositol"]

{"sheet":"gene","index":1,"n_rows":48,"n_cols":8,"rows_kept":48,"cut":false,"hidden":false,"merged":[],"flags":["formulas_cached_only"]}
["new genes in iBsu1147",{"$nulls":5},"removed genes from iBsu1103"]
["genes","name","description",null,null,null,"genes","comment"]
["BSU27510","iscS1 yrvO","cysteine desulfurase activity; metabolic process; pyridoxal phosphate binding",null,null,null,"yodU","replaced by BSU19810"]
["BSU15690","rpoZ yloH","DNA binding; DNA-directed RNA polymerase activity; transcription, DNA-dependent",null,null,null,"mnhE","replaced by BSU31640"]
["BSU02600","cwlJ ycbQ","cell wall; cellular cell wall organization; extracellular region; hydrolase activity; spore germination; sporulation resulting in formation of a cellular spore"]
["BSU03270","ycgT","FAD binding; NADP or NADPH binding; ferredoxin-NADP+ reductase activity; oxidation reduction"]
["BSU09880","yhaR","catalytic activity; integral to membrane; metabolic process; plasma membrane"]
["BSU12160","yjgC","2 iron, 2 sulfur cluster binding; 4 iron, 4 sulfur cluster binding; electron carrier activity; formate dehydrogenase activity; formate dehydrogenase complex; formate metabolic process; molybdenum ion binding; oxidation reduction"]
["BSU12230","yjjA","tetrapyrrole biosynthetic process; uroporphyrinogen-III synthase activity"]
["BSU12460","xlyB yjpB","N-acetylmuramoyl-L-alanine amidase activity; cell wall macromolecule catabolic process; cellular cell wall organization; establishment of competence for transformation; extracellular region; peptidoglycan catabolic process; sporulation resulting in formation of a cellular spore"]
["BSU12810","xlyA","N-acetylmuramoyl-L-alanine amidase activity; cell wall macromolecule catabolic process; cellular cell wall organization; establishment of competence for transformation; extracellular region; peptidoglycan catabolic process; sporulation resulting in formation of a cellular spore"]
["BSU13820","ykvT","cell wall; hydrolase activity; spore germination"]
["BSU16870","ymfI","binding; oxidation reduction; oxidoreductase activity"]
["BSU17160","pksH","antibiotic biosynthetic process; cytoplasm; lyase activity"]
["BSU17410","cwlC","N-acetylmuramoyl-L-alanine amidase activity; cell wall; cellular cell wall organization; establishment of competence for transformation; extracellular region; metal ion binding; peptidoglycan catabolic process; sporulation resulting in formation of a cellular spore"]
["BSU17640","alr2 yncD","alanine metabolic process; alanine racemase activity; cellular cell wall organization; peptidoglycan biosynthetic process; pyridoxal phosphate binding; regulation of cell shape"]
["BSU18570","yoaE","electron carrier activity; iron-sulfur cluster binding; molybdenum ion binding; oxidation reduction; oxidoreductase activity"]
["BSU20040","yosP yojQ/yojS","DNA replication; deoxyribonucleoside diphosphate metabolic process; oxidation reduction; ribonucleoside-diphosphate reductase activity; transition metal ion binding"]
["BSU20060","nrdEB yojP yosN","ATP binding; DNA replication; endonuclease activity; intein-mediated protein splicing; oxidation reduction; protein binding; ribonucleoside-diphosphate reductase activity; ribonucleoside-diphosphate reductase complex"]
["BSU20340","yorL","3'-5' exonuclease activity; DNA binding; DNA replication; DNA-directed DNA polymerase activity; cytoplasm"]
["BSU22230","ypqE","cytoplasm; kinase activity; membrane; phosphoenolpyruvate-dependent sugar phosphotransferase system; sugar:hydrogen symporter activity"]
["BSU22930","sleB ypeA","cell wall; cellular cell wall organization; hydrolase activity; intracellular immature spore; metabolic process; spore germination; sporulation resulting in formation of a cellular spore"]
["BSU25730","yqeC","NADP or NADPH binding; oxidation reduction; pentose-phosphate shunt; phosphogluconate dehydrogenase (decarboxylating) activity"]
["BSU25900","cwlA","N-acetylmuramoyl-L-alanine amidase activity; cellular cell wall organization; establishment of competence for transformation; extracellular region; peptidoglycan catabolic process; sporulation resulting in formation of a cellular spore"]
["BSU26810","yrpC","cellular cell wall organization; glutamate racemase activity; peptidoglycan biosynthetic process; regulation of cell shape"]
["BSU26970","adhB","oxidation reduction; oxidoreductase activity; zinc ion binding"]
["BSU27220","yrhE","2 iron, 2 sulfur cluster binding; 4 iron, 4 sulfur cluster binding; electron carrier activity; formate dehydrogenase activity; formate dehydrogenase complex; formate metabolic process; molybdenum ion binding; oxidation reduction"]
["BSU27770","yrbE","binding; oxidation reduction; oxidoreductase activity"]
["BSU27880","nifS iscS","cysteine desulfurase activity; metabolic process; pyridoxal phosphate binding"]
["BSU29420","ytkK","binding; oxidation reduction; oxidoreductase activity"]
["BSU29540","ppnK2 ytdI","ATP binding; NAD+ kinase activity; cytoplasm; metabolic process; metal ion binding"]
["BSU29590","iscS2 nifS2","cysteine desulfurase activity; metabolic process; pyridoxal phosphate binding"]
["BSU29980","ytjP","dipeptidase activity; metallopeptidase activity; protein binding; proteolysis; zinc ion binding"]
["BSU37100","murAB murA murZ","UDP-N-acetylgalactosamine biosynthetic process; UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity; cell cycle; cell division; cellular cell wall organization; cytoplasm; peptidoglycan biosynthetic process; regulation of cell shape"]
["BSU38460","tyrS2 tyrR tyrS1 tyrT tyrZ","tyrosyl-tRNA aminoacylation; cytoplasm; ATP binding; RNA binding; tyrosine-tRNA ligase activity"]
["BSU32500","pucB yurE","purine base metabolic process"]
["BSU32510","pucA yurF","oxidation reduction; purine base metabolic process; xanthine dehydrogenase activity"]
["BSU32460","pucM yunM","hydroxyisourate hydrolase activity; purine base metabolic process; transport"]
["BSU09670","dat yheM","D-alanine:2-oxoglutarate aminotransferase activity; D-amino acid biosynthetic process; D-amino acid catabolic process; pyridoxal phosphate binding"]
["BSU13730","queD ykvK","6-pyruvoyltetrahydropterin synthase activity; metal ion binding; queuosine biosynthetic process; tetrahydrobiopterin biosynthetic process"]
["BSU19810","yhaZ","binding"]
["BSU36560","ywnH","N-acetyltransferase activity; metabolic process; response to antibiotic; response to herbicide"]
["BSU37810","spsL","lipopolysaccharide biosynthetic process; dTDP-4-dehydrorhamnose 3,5-epimerase activity; oxidoreductase activity"]
["BSU37820","spsK","extracellular polysaccharide biosynthetic process; binding; dTDP-4-dehydrorhamnose reductase activity"]
["BSU32050","pepA yuiE","aminopeptidase activity; cytoplasm; manganese ion binding; metalloexopeptidase activity; proteolysis"]
["BSU31640","mrpE","proton transport; sodium ion transport; integral to membrane; plasma membrane; antiporter activity; cation transmembrane transporter activity"]
["BSU33530","yvaA","oxidoreductase"]
["BSU39680","iolI","sugar-phosphate epimerase/isomerase"]