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["Table S4. Summary of the findings of the study"]
["Basis for hypothesis","Hypothesis","Experiments performed to validate to hypothesis","Experimental results for snf1Δ/snf1Δ (wrt wild type)","Ultimate outcome"]
["Snf1p is a focal node of SSN","Snf1p impacts sphingolipid biosynthesis","complex sphingolipid profile ","altered (increased IPC & MIPC, decreased M(IP)2C) (Figures 4&5)","Snf1p has a regulatory role on sphingolipid biosynthesis"]
[null,null,"resistance to myriocin","increased  (Figure 10a)"]
[null,null,"dosage and treatment-time dependent response to myriocin","yes (Figures 10 & 11)"]
["Enrichment results of important genes","Snf1p and sphingolipids crosstalk with Ca2+-mediated signaling","resistance to CaCl2+myriocin","decreased (Figure 12b)"," Snf1p is needed for overactive calcineurin in response to myriocin"]
[null,null,"resistance to FK506+myriocin","unchanged (Figure 12b)"]
[null,null,"resistance to CaCl2+ FK506+myriocin","decreased (Figure 12b)"]
[null,"Snf1p and sphingolipids crosstalk in iron homeostasis","resistance to BPS+myriocin","unchanged (Figure 13b)"," Snf1p is needed for resistance to iron when sphingolipid synthesis is disrupted"]
[null,null,"resistance to FeCl3+myriocin","decreased (Figure 13b)"]
[null,"Snf1p and sphingolipids crosstalk in ER stress","resistance to myriocin","decreased on DTT supplemented medium (Figure 14)"," Snf1p is needed for resistance to ER stress when sphingolipid synthesis is disrupted"]
[null,null,"resistance to myriocin","decreased on TM supplemented medium (Figure 14)"]
[null,"Snf1p and sphingolipids crosstalk in CW stress","resistance to myriocin","decreased on AC supplemented medium (Figure 14)"," Snf1p is needed for resistance to CW stress when sphingolipid synthesis is disrupted"]
[null,null,"resistance to myriocin","decreased on SDS supplemented medium (Figure 14)"]

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