Additions and corrections

Palladium-Catalyzed Coupling of Functionalized Primary and Secondary Amines with Aryl and Heteroaryl Halides: Two Ligands Suffice in Most Cases

Debabrata Maiti, Brett P. Fors, Jaclyn L. Henderson, Yoshinori Nakamura and Stephen L. Buchwald*

Chem. Sci., 2011, 2, 57-68 DOI: 10.1039/c0sc00330a Amendment published 25th March 2011

In the supplementary information of our manuscript General Procedure H lists the incorrect catalyst system. The correct procedure is as follows:

General procedure H. An oven-dried test tube, which was equipped with a magnetic stir bar and fitted with a teflon septum, was charged with the RuPhos precatalyst 4 (0.25 mol% or as indicated) and RuPhos 2 (0.25 mol% or as indicated). The vessel was evacuated and backfilled with argon (this process was repeated a total of 3 times) and then the aryl halide (1.0 mmol or as indicated), amine (1.2 mmol or as indicated), and a solution of LHMDS in THF (2.2 mmol, 1.0 M in THF) were added via syringe (aryl chlorides and amines that were solids at room temperature were added with the catalyst). The solution was heated in an oil bath at 65 C while stirring for 8 h (or indicated temperature and period of time). The reaction mixture was then cooled to room temperature, diluted with CH2Cl2, washed with water, dried over Na2SO4, concentrated in vacuo, and purified via the Biotage SP4 (silica- packed SNAP cartridge, KP-Sil, 10 g) using mixture of hexane and ethyl acetate.

We thank a reader for bringing this to our attention.

The Royal Society of Chemistry apologises for this error and any consequent inconvenience to authors and readers.

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