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Chem. Commun., 2003, 1781 - 1785, DOI: 10.1039/b304015c
Nonenzymatic peptide-based catalytic asymmetric phosphorylation of inositol derivatives
Bianca R. Sculimbrene, Adam J. Morgan and Scott J. Miller
The ability to use small peptides as catalysts for asymmetric phosphorylation provides opportunities for rapid syntheses of phosphate-containing compounds and natural products. This short review outlines the genesis of this concept and its reduction to practice in the context of concise syntheses of the enantiomeric D-I-1P and D-I-3P targets. The implications for the development of additional site-selective catalysts are discussed.
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