Issue 14, 2006
From the journal:

Chemical Communications

Spectroscopic detection of Saxitoxin: an alternative to mouse bioassay

Péter Kele,a   Jhony Orbulescu,b   Robert E. Gawleyc  and  Roger M. Leblanc*b  

* Corresponding authors

a Department of Chemistry, Eötvös Loránd University, Pazmany Peter setany 1/A, VI. Emelet 646 szoba, Budapest, Hungary

b Department of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, USA
E-mail: rml@miami.edu
Fax: +1(305) 284-6367
Tel: +1(305)284-2194

c Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, USA

Abstract

Herein, we report the surface modification of quartz with a coumaryl–aza-crown-6 derivative to detect Saxitoxin using fluorescence enhancement through Photoinduced Electron Transfer and the sensitivity with this system approaches the limit of the mouse bioassay which is the current benchmark for Saxitoxin detection.

Graphical abstract: Spectroscopic detection of Saxitoxin: an alternative to mouse bioassay

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Article information

DOI
https://doi.org/10.1039/B600383D
Article type
Communication
Submitted
10 Jan 2006
Accepted
30 Jan 2006
First published
23 Feb 2006

Chem. Commun., 2006, 1494-1496

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Spectroscopic detection of Saxitoxin: an alternative to mouse bioassay

P. Kele, J. Orbulescu, R. E. Gawley and R. M. Leblanc, Chem. Commun., 2006, 1494 DOI: 10.1039/B600383D

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