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Feature Article
Chem. Commun., 2010, 46, 21 - 43, DOI: 10.1039/b913845e
Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins
Richard J. Payne and Chi-Huey Wong
A number of recent advances in the chemical synthesis of glycopeptides and glycoproteins are described, with particular focus on the development of peptide ligation strategies and their implementation in the convergent assembly of complex glycopeptides. Recent applications in the synthesis of full length homogeneous glycoproteins are also highlighted.
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