Issue 4, 2010
From the journal:

Chemical Society Reviews

Fluorogenic click reaction†

Céline Le Droumaguet,a   Chao Wangab  and  Qian Wang*a  

* Corresponding authors

a Department of Chemistry and Biochemistry and Nanocenter, University of South Carolina, 631 Sumter Street, Columbia, SC, USA
E-mail: wang@mail.chem.sc.edu
Web: http://www.chem.sc.edu/people/facultyStaffDetails.asp?SID=245
Fax: +1 803 777 9521
Tel: +1 803 777 8436

b Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China

Abstract

Fluorogenic Cu(I)-catalyzed alkyne–azide cycloaddition (CuAAC) reactions have emerged as a powerful tool for bioconjugation, materials science, organic synthesis and drug discovery. This review highlights the design of the recent development of fluorogenic CuAAC reactions as well as their applications.

Graphical abstract: Fluorogenic click reaction

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Article information

DOI
https://doi.org/10.1039/B901975H
Article type
Tutorial Review
Submitted
22 Jun 2009
First published
30 Sep 2009

Chem. Soc. Rev., 2010,39, 1233-1239

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Fluorogenic click reaction

C. Le Droumaguet, C. Wang and Q. Wang, Chem. Soc. Rev., 2010, 39, 1233 DOI: 10.1039/B901975H

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