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Interview: The frontiers of medicine
04 June 2009
Wilfred van der Donk tells Rachel Cooper about investigating enzymes and the choice between history and science
Issue 6 of NPR now online
29 May 2009
The latest issue of Natural Product Reports is now available online
IUPAC 2009 Programme Now Available
28 April 2009
Speakers and titles of lectures for the congress taking place 2-7 August 2009 in Glasgow, UK are now online. Early booking deadline - 5 June 2009.
NPR news archive
Contents list for Natural Product Reports, issue 7, 2009
Front cover
Nat. Prod. Rep., 2009, 26, 857
DOI: 10.1039/b911405j
Contents and Chemical Biology
Nat. Prod. Rep., 2009, 26, 859
DOI: 10.1039/b911406h
Highlights
Synthesis and stereochemical determination of the spirastrellolides
Ian Paterson and Stephen M. Dalby,
Nat. Prod. Rep., 2009, 26, 865
DOI: 10.1039/b906991g
This Highlight summarises synthetic efforts towards the marine sponge-derived antimitotic agent spirastrellolide A and its congeners, including the first total synthesis by Paterson and co-workers.
Bioinformatic perspectives on NRPS/PKS megasynthases: Advances and challenges
Holger Jenke-Kodama and Elke Dittmann,
Nat. Prod. Rep., 2009, 26, 874
DOI: 10.1039/b810283j
Computational analysis of NRPSs and PKSs has become an important tool in natural product research. Here, we review bioinformatic studies on evolution, structural prediction, protein–protein interactions and public databases.
Reviews
Blue flower color development by anthocyanins: from chemical structure to cell physiology
Kumi Yoshida, Mihoko Mori and Tadao Kondo,
Nat. Prod. Rep., 2009, 26, 884
DOI: 10.1039/b800165k
Blue flower coloration is mainly caused by an unstable anhydrobase-anion form of anthocyanin in petal-cell vacuoles. This review covers the various sophisticated mechanisms by which this structure is stabilized.
Natural stilbenes: an overview
Tao Shen, Xiao-Ning Wang and Hong-Xiang Lou,
Nat. Prod. Rep., 2009, 26, 916
DOI: 10.1039/b905960a
From January 1995 to the end of 2008, more than 400 naturally occurring stilbenes have been isolated and identified. This review covers their structural diversity, distribution, and bioactivity.
The Daphniphyllum alkaloids
Jun'ichi Kobayashi and Takaaki Kubota,
Nat. Prod. Rep., 2009, 26, 936
DOI: 10.1039/b813006j
This review covers the isolation, structure elucidation, synthesis, biosynthesis and bioactivity of the Daphniphyllum alkaloids reported up to 2008.
Back cover
Nat. Prod. Rep., 2009, 26, 963
DOI: 10.1039/b911411b
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