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Natural Product Reports

High impact, critical reviews in natural products research and related areas



Latest News

Richard Kelly

New Editor announcement

26 January 2010

We are pleased to announce Richard Kelly as the new Editor of Organic & Biomolecular Chemistry and Natural Product Reports.


Christopher Walsh

NPR Lecture Award winner 2010 announced

25 January 2010

The 2010 Natural Product Reports Lecture Award has been won by Professor Christopher Walsh, at Harvard Medical School, in the US.


Michael Burkart

OBC Lecture Award winner 2010 announced

25 January 2010

The 2010 OBC Lecture Award has been won by Professor Michael Burkart, at the University of California - San Diego, in the US.


NPR news archive

NPR news archive


  • Advance Articles


Contents list for Natural Product Reports, issue 2, 2010

RSS news feed image for latest articles

Front cover
Nat. Prod. Rep., 2010, 27, 141
DOI: 10.1039/c000850h

front cover image for Natural Product Reports, Issue 2, 2010

Contents
Nat. Prod. Rep., 2010, 27, 143
DOI: 10.1039/c000851f

Hot off the Press Article

Hot off the press
Robert A. Hill and Andrew Sutherland,  Nat. Prod. Rep., 2010, 27, 149
DOI: 10.1039/b926722k

graphical abstract image (ID: b926722k)

A personal selection of 29 recent papers is presented covering various aspects of current developments in bioorganic chemistry and novel natural products such as alasmontamine A from Tabernaemontana elegans.

Highlight

Recent advances in thiopeptide antibiotic biosynthesis
Chaoxuan Li and Wendy L. Kelly,  Nat. Prod. Rep., 2010, 27, 153
DOI: 10.1039/b922434c

graphical abstract image (ID: b922434c)

Thiopeptide antibiotics were recently found to be the products of an extensive collection of post-translational modifications. This Highlight discusses the biosynthetic insights gained during the first portion of 2009.

Reviews

Marine natural products
John W. Blunt, Brent R. Copp, Murray H. G. Munro, Peter T. Northcote and Michèle R. Prinsep,  Nat. Prod. Rep., 2010, 27, 165
DOI: 10.1039/b906091j

graphical abstract image (ID: b906091j)

This review describes the 1076 new marine natural products reported in 2008. One of these was the potent antiproliferative largazole, remarkable for the thioester functionality and the seven total syntheses reported in 2008.

Antimicrobial natural products: an update on future antibiotic drug candidates
Muhammad Saleem, Mamona Nazir, Muhammad Shaiq Ali, Hidayat Hussain, Yong Sup Lee, Naheed Riaz and Abdul Jabbar,  Nat. Prod. Rep., 2010, 27, 238
DOI: 10.1039/b916096e

graphical abstract image (ID: b916096e)

This review deals with the potential antimicrobial natural products reported during 2000–2008 that have activities in the range 0.02–10.0 g mL-1, together with their mode of action where this is known.

PKS and NRPS release mechanisms
Liangcheng Du and Lili Lou,  Nat. Prod. Rep., 2010, 27, 255
DOI: 10.1039/b912037h

graphical abstract image (ID: b912037h)

This review covers the recent literature on the release mechanisms for polyketides and nonribosomal peptides produced by microorganisms. The emphasis is on the novel enzymology and mechanistic insights revealed by the biosynthetic studies of new natural products.

Antimicrobial nucleoside antibiotics targeting cell wall assembly: Recent advances in structure–function studies and nucleoside biosynthesis
Michael Winn, Rebecca J. M. Goss, Ken-ichi Kimura and Timothy D. H. Bugg,  Nat. Prod. Rep., 2010, 27, 279
DOI: 10.1039/b816215h

graphical abstract image (ID: b816215h)

This review describes new structures and structure–function studies on nucleoside antibiotics targeting cell wall biosynthesis, and recent studies on their biosynthesis.

Back matter
Nat. Prod. Rep., 2010, 27, 305
DOI: 10.1039/c000852b

Back cover
Nat. Prod. Rep., 2010, 27, 311
DOI: 10.1039/c000853m