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Chem. Commun., 2006, 3226 - 3228, DOI: 10.1039/b606583j

3-Hydroxypyrrolidines from epoxysulfonamides and dimethylsulfoxonium methylide

David M. Hodgson, Matthew J. Fleming, Zhaoqing Xu, Changxue Lin and Steven J. Stanway

N-Tosyl-protected 3-hydroxypyrrolidines are prepared by reaction of dimethylsulfoxonium methylide with readily available epoxysulfonamides.

Graphical abstract image for this article (ID: b606583j)