Issue 30, 2006
From the journal:

Chemical Communications

3-Hydroxypyrrolidines from epoxysulfonamides and dimethylsulfoxonium methylide†

David M. Hodgson,*a   Matthew J. Fleming,a   Zhaoqing Xu,a   Changxue Lina  and  Steven J. Stanway‡a  

* Corresponding authors

a Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, UK
E-mail: david.hodgson@chem.ox.ac.uk

Abstract

N-Tosyl-protected 3-hydroxypyrrolidines are prepared by reaction of dimethylsulfoxonium methylide with readily available epoxysulfonamides.

Graphical abstract: 3-Hydroxypyrrolidines from epoxysulfonamides and dimethylsulfoxonium methylide

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Article information

DOI
https://doi.org/10.1039/B606583J
Article type
Communication
Submitted
10 May 2006
Accepted
26 May 2006
First published
22 Jun 2006

Chem. Commun., 2006, 3226-3228

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3-Hydroxypyrrolidines from epoxysulfonamides and dimethylsulfoxonium methylide

D. M. Hodgson, M. J. Fleming, Z. Xu, C. Lin and S. J. Stanway, Chem. Commun., 2006, 3226 DOI: 10.1039/B606583J

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