Issue 2, 2008
From the journal:

Chemical Communications

Chain-like assembly of gold nanoparticles on artificial DNA templates via ‘click chemistry’†

Monika Fischler,a   Alla Sologubenko,b   Joachim Mayer,b   Guido Clever,c   Glenn Burley,‡c   Johannes Gierlich,c   Thomas Carellc  and  Ulrich Simon*a  

* Corresponding authors

a Institut für Anorganische Chemie, RWTH Aachen, Landoltweg 1, Germany
E-mail: ulrich.simon@ac.rwth-aachen.de
Fax: +49 (0) 241 8099003
Tel: +49 (0) 241 8094644

b Gemeinschaftslabor für Elektronenmikrosokopie, RWTH Aachen, Ahornstraße 55, Germany

c Fakultät für Chemie und Pharmazie, LMU München, Butenandtstr. 5-13 (Haus F), Germany

Abstract

We present a new type of azide-functionalized gold nanoparticle and their coupling to an alkyne-modified DNA duplex using the copper(I)-catalyzed Huisgen cycloaddition (‘click chemistry’), resulting in a chain-like assembly of nanoparticles on the DNA template.

Graphical abstract: Chain-like assembly of gold nanoparticles on artificial DNA templates via ‘click chemistry’

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Article information

DOI
https://doi.org/10.1039/B715602B
Article type
Communication
Submitted
10 Oct 2007
Accepted
22 Nov 2007
First published
29 Nov 2007

Chem. Commun., 2008, 169-171

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Chain-like assembly of gold nanoparticles on artificial DNA templates via ‘click chemistry’

M. Fischler, A. Sologubenko, J. Mayer, G. Clever, G. Burley, J. Gierlich, T. Carell and U. Simon, Chem. Commun., 2008, 169 DOI: 10.1039/B715602B

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