Issue 26, 2010

Electrosprayed core–shell microspheres for protein delivery

Abstract

This communication describes a single-step electrospraying technique that generates core–shell microspheres (CSMs) with encapsulated protein as the core and an amphiphilic biodegradable polymer as the shell. The protein release profiles of the electrosprayed CSMs showed steady release kinetics over 3 weeks without a significant initial burst.

Graphical abstract: Electrosprayed core–shell microspheres for protein delivery

Article information

Article type
Communication
Submitted
22 Mar 2010
Accepted
05 May 2010
First published
20 May 2010

Chem. Commun., 2010,46, 4743-4745

Electrosprayed core–shell microspheres for protein delivery

Y. Wu, I. Liao, S. J. Kennedy, J. Du, J. Wang, K. W. Leong and R. L. Clark, Chem. Commun., 2010, 46, 4743 DOI: 10.1039/C0CC00535E

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