Twenty Years of the Rule of Five

20 November 2019, Nottingham, United Kingdom


Introduction
Synopsis
It has been over twenty years since Lipinski published his work determining the properties of drug molecules associated with good solubility and permeability. Since then, there have been a number of additions and expansions to these “rules”. There has also been keen interest in the application of these guidelines in the drug discovery process and how these apply to new emerging chemical structures such as macrocycles. 

This symposium will bring together researchers from a number of different areas of drug discovery and will provide a historical overview of the use of Lipinski’s rules, as well as looking to the future and how we use these rules in the changing drug compound landscape. 

Features of the Meeting
  • Historical look at the use of the Rule of Five
  • New parameters used in drug discovery
  • Look forward to the next 20 years
  • Panel discussions in each session
  • Plenary speakers, poster session, and drinks reception
Who should attend
Scientists from industry and academia, including medicinal and computational chemists

Call for Short Talk and Poster Abstracts
Applications for oral and poster presentations are invited. Short talks within the theme of historical use of the Rule of Five or looking forward and beyond the Rule of Five are welcomed. Posters will be displayed throughout the day. The closing dates are 30th June (oral) and 6th October 2019 (posters). 

Registration Fees
£120 RSC member
£165 Non-member
  £50 RSC student* member
  £80 Student* non-member
* Student is undergraduate or post-graduate, not post-doc
Member is a paid-up member of the RSC. A late fee of £30 will apply to payments received from 19th October onwards.

Students and Bursaries
A number of RSC-BMCS and RSC-CICAG student bursaries are available up to a value of £250, to support registration, travel and accommodation costs for PhD and post-doctoral applicants studying at European academic institutions. The closing date for bursary applications is 4th October. 

Travel
East Midlands airport is just 20 minutes away, and regular trains run direct from London (journey time two hours).  Sygnature Discovery is just over half-a-mile from the railway station. 
Speakers
Sponsorship & supporting organisations
Venue
Sygnature Discovery Ltd

Innovation Building, Sygnature Discovery Ltd, BioCity, Pennyfoot Street, Nottingham, NG1 1GR , United Kingdom

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