Mass Spectral Interpretation for LC-MS

4 - 6 March 2019, Milton Keynes, United Kingdom

If you wish to learn the fundamentals of LC-MS mass spectral interpretation for the identification of unknowns or to enhance your understanding of fragmentation patterns, to assist in accurate identification when using library search programs, then this course is for you.

This three-day course is an introduction to mass spectral interpretation presenting the fundamental tools and rules when interpreting full-scan LC-MS data. The delegates will benefit from a greater understanding of how to interpret the mass spectra produced by Electrospray Ionisation (ESI) and Atmospheric Pressure Chemical Ionisation (APCI).

From learning to quickly recognise from the spectrum if the analyte is aliphatic or aromatic in nature; to learning to interpret the number of carbon atoms, heteroatoms and degree of unsaturation; and understand isotopes, isomers, logical losses, cleavages and rearrangements to produce a mass spectral fingerprint of the compound.

The course uses a combination of classroom-based presentations to introduce the theory with a high proportion of exercises on LC-MS spectral data.

This course is recommended for those who have a good background in organic chemistry and at least six months experience as a LC-MS operator, and is interested in structural elucidation of compounds amenable to analysis by LC-MS.
The Open University

The Open University, Walton Hall, Kents Hill, Milton Keynes, MK7 6AA, United Kingdom

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Anthias Consulting Ltd are experts in the separation science fields of Gas Chromatography (GC, GCxGC) and Liquid Chromatography (HPLC, UHPLC, LCxLC), Mass Spectrometry (GC-MS, LC-MS, ICP-MS), Spectroscopy (ICP-OES, IR, UV/Vis, AA) and all related techniques.
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