Integrin Targeted Drug Discovery

28 March 2019 09:00-17:00, London, United Kingdom

Integrins are heterodimeric, transmembrane receptors that function in cell adhesion and signalling. They are central to many disease states, including cancer, thrombosis, multiple sclerosis and Crohn’s disease. Integrin targeted therapeutics have been under investigation for some time, but few compounds have made it to/ remained on the market due to side effects or lack of efficacy. Given the more recent structural insights, better understanding of downstream pathways, and potential application to a range of therapeutic areas, there has been a resurgence of interest in integrin inhibitors. This symposium will bring together researchers in this area to provide both a historical overview of the area and recent progress in designing the next generation of integrin inhibitors.

Who should attend
Scientists from industry and academia, including medicinal and computational chemists.

Features of the Meeting
Therapeutic targets for integrins
Targeting different RGD recognising integrins
Drug discovery, medicinal chemistry and structure-based design
Plenary speakers, poster session and trade exhibition

Call for Abstracts
Applications for oral and poster presentations are welcomed. Posters will be displayed throughout the day, and applicants will be asked if they would like to provide a two-minute flash oral presentation when submitting their abstract. Closing dates are 30th June 2018 for oral and 31st December 2018 for poster submissions.

Registration will open in Spring 2018, and discounted rates will be available for students and RSC members. In addition, a number of student bursaries will be available for post-graduate students.

A relevant trade exhibition will add value to the symposium.   The exhibition will be held in the same room as the catering (refreshments and lunch) and posters, and the exhibition package will include:
- chair and table
- electrical access and wi-fi access
- one full delegate attendance.

Those companies wishing to have a trade stand should register an interest with the secretariat.  There will be an opportunity to book delegate pack inserts.

Venue and Travel
The symposium will be held in the Science and Fish Rooms, Royal Society of Chemistry at Burlington House, Piccadilly, London, W1J 0BA, UK.  Situated in central London, the RSC is easily accessible by public transport, and close to Green Park tube station.

Sponsors are encouraged to support this event, which will help us to offer inexpensive registration fees to young chemists.
The Royal Society of Chemistry

Science and Fish Rooms, The Royal Society of Chemistry, Burlington House, Piccadilly, London, W1J 0BA, United Kingdom

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