Hofmann elimination

Definition: The elimination of a methylated amine from an alkylamine to form an olefin. The reaction proceeds via the quaternary ammonium salt.

ID: RXNO:0000166

Synonyms:

More about the RSC Name Reaction Ontology (RXNO)

Articles referencing this term

Chemo-/regioselective synthesis of 6-unsubstituted dihydropyrimidinones, 1,3-thiazines and chromones via novel variants of Biginelli reaction
Jie-Ping Wan and Yuan-Jiang Pan, Chem. Commun., 2009 , 2768
DOI: 10.1039/b901112a

Efficient ruthenium-catalyzed synthesis of [3]dendralenes from 1,3-dienic allylic carbonates
Kassem Beydoun, Hui-Jun Zhang, Basker Sundararaju, Bernard Demerseman, Mathieu Achard, Zhenfeng Xi and Christian Bruneau, Chem. Commun., 2009 , 6580
DOI: 10.1039/b913595b

Solvent-free microwave-assisted multi-component reaction for preparation of 2-amino-1-aryl-2-(cyclohex-1-enyl)ethanones as precursors of pseudoephedrine analogues
Li-Jian Ma and Tsutomu Inokuchi, Chem. Commun., 2010 , 46 , 7037
DOI: 10.1039/c0cc00859a