Phishing warning 01-May-2024
We are aware of phishing emails targeting speakers of events whose names appear on our events pages. If you are unsure if an email regarding event registration or accommodation has come from us please contact us and do not provide any credit card details or personal information

Pharmaceutical Dissolution Testing - a Hands-on course

3 - 5 November 2015, London, United Kingdom

To achieve reliable and reproducible results, it is important that analysts understand the importance of correctly setting up and sampling from the chosen apparatus. In addition to use of dissolution testers, this three-day course will also cover equipment qualification, development and validation of dissolution procedures, and the use of dissolution testing in the assessment of bioavailability and bioequivalence. Delegates will have the opportunity to set up and run dissolution tests using a USP I/II dissolution tester during the course.

Who should attend?
This course is aimed at those new to dissolution testing and analysts with previous experience seeking to improve their skills and knowledge.


Day 1
Why do we perform dissolution testing?
Dissolution theory, sink conditions and intrinsic dissolution rate
Dissolution and drug release testing apparatus
* Rotating basket (USP Apparatus 1)
* Rotating paddle (USP Apparatus 2)
* Reciprocating cylinder (USP Apparatus 3)
* Flow-through cell (USP Apparatus 4)
* Paddle over disc (USP Apparatus 5)
* Rotating cylinder (USP Apparatus 6)
* Reciprocating holder (USP Apparatus 7)
* Franz cell
Practical session: setting up a dissolution tester with basket and paddle apparatus

Day 2
Requirements for different dosage form types (including data interpretation)
* Immediate release
* Extended release
* Delayed release
* Transdermal delivery systems
Dissolution equipment qualification
Practical session: delegates will perform a dissolution test on an immediate release drug product

Day 3
Dissolution method development
* General requirements
* Selection of dissolution medium
* Apparatus and agitation
* Sampling (time points & filtration)
* Assay requirements
Dissolution method validation
* Setting acceptance criteria with reference to drug product specifications
* Specificity
* Linearity/range
* Accuracy/recovery
* Precision
* Robustness
* Solution stability
Dissolution and the assessment of bioavailability/bioequivalence

DoubleTree Hilton Islington

DoubleTree Hilton Islington , 60 Pentonville Road, London, EC1V 2NX, United Kingdom

Organised by
PharmaCourses Ltd
Contact information
Showing all upcoming events
Start Date
End Date
Subject area
Event type


E-mail Enquiry