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Fully booked: Twenty Years of the Rule of Five

20 November 2019, Nottingham, United Kingdom

It has been over twenty years since Lipinski published his work determining the properties of drug molecules associated with good solubility and permeability. Since then, there have been a number of additions and expansions to these “rules”. There has also been keen interest in the application of these guidelines in the drug discovery process and how these apply to new emerging chemical structures such as macrocycles. 

This symposium will bring together researchers from a number of different areas of drug discovery and will provide a historical overview of the use of Lipinski’s rules, as well as looking to the future and how we use these rules in the changing drug compound landscape. 

Features of the Meeting
  • Historical look at the use of the Rule of Five
  • New parameters used in drug discovery
  • Look forward to the next 20 years
  • Panel discussions in each session
  • Poster session, and drinks reception
Who should attend
Scientists from industry and academia, including medicinal and computational chemists

Call for Poster Abstracts
Applications for poster presentations are invited within the theme of historical use of the Rule of Five or looking forward and beyond the Rule of Five.  Posters will be displayed throughout the day and the closing date is 6th October 2019.

Registration Fees
£120 RSC member
£165 Non-member
  £50 RSC student* member
  £80 Student* non-member
* Student is undergraduate or post-graduate, not post-doc
Member is a paid-up member of the RSC. A late fee of £30 will apply to payments received from 19th October onwards.

Students and Bursaries
A number of RSC-BMCS and RSC-CICAG student bursaries are available up to a value of £250, to support registration, travel and accommodation costs for PhD and post-doctoral applicants studying at European academic institutions. The closing date for bursary applications is 4th October. 

East Midlands airport is just 20 minutes away, and regular trains run direct from London (journey time two hours).  Sygnature Discovery is just over half-a-mile from the railway station. 
  • Elisabetta Chiarparin AstraZeneca, United Kingdom
  • Phil Cox AbbVie, United States
  • Paul Leeson Consultant, United Kingdom
  • Jean-Louis Reymond University of Bern, Switzerland
  • Tim Ritchie Consultant, United Kingdom
  • Michael Shultz Novartis, United States
  • Jóhannes Reynisson Keele University, United Kingdom
  • James Thompson GlaxoSmithKline, United Kingdom
  • John Priestner GlaxoSmithKline, United Kingdom

Sponsorship & supporting organisations
Sygnature Discovery Ltd

Innovation Building, Sygnature Discovery Ltd, BioCity, Pennyfoot Street, Nottingham, NG1 1GR , United Kingdom

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