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17th EFMC Short Course on Medicinal Chemistry

23 - 26 April 2023, Oegstgeest, Netherlands


Small Molecule Protein Degraders: A New Opportunity for Drug Design and Development

This intensive course is intended for scientists working in the field, and the presentations will be given by senior scientists from industry and academia. The number of participants is limited to 35, to allow in depth discussion.

Course Outline

In the last ten years there have been significant developments in the field of designing small molecule protein degraders both as chemical tools and clinical candidates. These degraders can offer major advantages over small molecule inhibitors as a therapeutic strategy by achieving more complete target inhibition and by expanding the potentially druggable proteome. This course aims to provide opportunities for in depth discussions on the key aspects of PROTAC design and development for medicinal chemists. It will finish with a series of medicinal chemistry case studies, including the discovery of clinical small molecule protein degraders.
Castle Oud Poelgeest

Castle Oud Poelgeest, Poelgeesterweg 1, Oegstgeest, 2341 NM, Netherlands

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