Introduction

Small Molecule Protein Degraders: A New Opportunity for Drug Design and Development

This intensive course is intended for scientists working in the field, and the presentations will be given by senior scientists from industry and academia. The number of participants is limited to 35, to allow in depth discussion.

Course Outline

In the last ten years there have been significant developments in the field of designing small molecule protein degraders both as chemical tools and clinical candidates. These degraders can offer major advantages over small molecule inhibitors as a therapeutic strategy by achieving more complete target inhibition and by expanding the potentially druggable proteome. This course aims to provide opportunities for in depth discussions on the key aspects of PROTAC design and development for medicinal chemists. It will finish with a series of medicinal chemistry case studies, including the discovery of clinical small molecule protein degraders.

Deadlines

• Mar 10 2023
  Early bird registration deadline

  

Useful links

• Further event details More information about the event

Speakers

• Dr Chun-wa Chung GlaxoSmithKline, United Kingdom

  https://www.linkedin.com/in/chun-wa-chung-5b8120b/?originalSubdomain=uk
• Professor Alessio Ciulli University of Dundee, United Kingdom

  https://www.dundee.ac.uk/people/alessio-ciulli
• Dr Suzanne O'Connor University of Dundee, United Kingdom

  https://www.linkedin.com/in/suzanne-o-connor/?originalSubdomain=uk
• Dr Danette Daniels Foghorn Therapeutics, United States

  https://www.linkedin.com/in/danette-daniels-she-her-45648924/
• Dr Ingo Hartung Merck KGaA, Germany

  https://www.linkedin.com/in/ingo-hartung-4145326/?originalSubdomain=de
• Dr Andrea Testa Amphista Therapeutics, United Kingdom

  https://amphista.com/portfolio-item/andrea-testa/

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Venue

Castle Oud Poelgeest

Castle Oud Poelgeest, Poelgeesterweg 1, Oegstgeest, 2341 NM, Netherlands

Useful links

• Venue information More information about the venue

Committee

• Professor Alessio Ciulli University of Dundee, United Kingdom

  https://www.dundee.ac.uk/people/alessio-ciulli
• Dr Suzanne O'Connor University of Dundee, United Kingdom

  https://www.linkedin.com/in/suzanne-o-connor/?originalSubdomain=uk
• Professor Laura Heitman University of Leiden, Netherlands

  https://www.universiteitleiden.nl/en/staffmembers/laura-heitman#tab-1

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Contact information

LD Organisation
Rue Michel de Ghelderode 33/02
BE B-1348 Louvain-la-Neuve
+32 (0)10 45 47 77
Contact us by email

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