Trituration

Definition: A process used to purify crude chemical compounds containing solid impurities. A solvent is chosen in which the desired product is insoluble and the undesired by-products are very soluble (or vice versa). The crude material is washed with the solvent and filtered away, leaving the purified product in solid form and any impurities in solution.

ID: CMO:0002066

More about the RSC Chemical Methods Ontology (CMO)

Articles referencing this term

Single-cell transcript analysis of human embryonic stem cells
Jason D. Gibson, Caroline M. Jakuba, Nathalie Boucher, Kelly A. Holbrook, Mark G. Carter and Craig E. Nelson, Integr. Biol., 2009 , 1 , 540
DOI: 10.1039/b908276j

One-pot synthesis of substituted isoindolin-1-ones via lithiation and substitution of N′-benzyl-N,N-dimethylureas
Keith Smith, Gamal A. El-Hiti and Amany S. Hegazy, Chem. Commun., 2010 , 46 , 2790
DOI: 10.1039/b926983e