Urea cycle


Definition: The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate.

ID: GO:0000050

Synonyms:

Articles referencing this term

Systems biology of antibiotic production by microorganisms
J. Stefan Rokem, Anna Eliasson Lantz and Jens Nielsen, Nat. Prod. Rep., 2007 , 24 , 1262
DOI: 10.1039/b617765b

A genome-scale, constraint-based approach to systems biology of human metabolism
Monica L. Mo, Neema Jamshidi and Bernhard Ø. Palsson, Mol. BioSyst., 2007 , 3 , 598
DOI: 10.1039/b705597h

Genome-scale reconstruction of the metabolic network in Yersinia pestis, strain 91001
Ali Navid and Eivind Almaas, Mol. BioSyst., 2009 , 5 , 368
DOI: 10.1039/b818710j

A synthetic metabolite-based mammalian inter-cell signaling system
Wilfried Weber, Marco Schuetz, Nicolas Dénervaud and Martin Fussenegger, Mol. BioSyst., 2009 , 5 , 757
DOI: 10.1039/b902070p

Mitochondrial proteomics and its application in biomedical research
Cristina Ruiz-Romero and Francisco J. Blanco, Mol. BioSyst., 2009 , 5 , 1130
DOI: 10.1039/b906296n

The powerful law of the power law and other myths in network biology
Gipsi Lima-Mendez and Jacques van Helden, Mol. BioSyst., 2009 , 5 , 1482
DOI: 10.1039/b908681a

Metabolic profiling of the fission yeast S. pombe: quantification of compounds under different temperatures and genetic perturbation
Tomáš Pluskal, Takahiro Nakamura, Alejandro Villar-Briones and Mitsuhiro Yanagida, Mol. BioSyst., 2010 , 6 , 182
DOI: 10.1039/b908784b

Genome-scale metabolic network analysis and drug targeting of multi-drug resistant pathogen Acinetobacter baumannii AYE
Hyun Uk Kim, Tae Yong Kim and Sang Yup Lee, Mol. BioSyst., 2010 , 6 , 339
DOI: 10.1039/b916446d


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