Receptor-mediated endocytosis

Definition: An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.

ID: GO:0006898

Synonyms:

Articles referencing this term

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Jian Yang, Jonathan Gunn, Shivang R. Dave, Miqin Zhang, Y. Andrew Wang and Xiaohu Gao, Analyst, 2008 , 133 , 154
DOI: 10.1039/b700091j

Polymeric nanovehicles for anticancer drugs with triggering release mechanisms
Kyung T. Oh, Haiqing Yin, Eun Seong Lee and You Han Bae, J. Mater. Chem., 2007 , 17 , 3987
DOI: 10.1039/b707142f

Effective and efficient sensitisation of terbium luminescence at 355 nm with cell permeable pyrazoyl-1-azaxanthone macrocyclic complexes
Craig P. Montgomery, David Parker and Laurent Lamarque, Chem. Commun., 2007 , 3841
DOI: 10.1039/b709805g

Potential roles of abundant extracellular chaperones in the control of amyloid formation and toxicity
Mark R. Wilson, Justin J. Yerbury and Stephen Poon, Mol. BioSyst., 2008 , 4 , 42
DOI: 10.1039/b712728f

A general map of iron metabolism and tissue-specific subnetworks
Valerie Hower, Pedro Mendes, Frank M. Torti, Reinhard Laubenbacher, Steven Akman, Vladmir Shulaev and Suzy V. Torti, Mol. BioSyst., 2009 , 5 , 422
DOI: 10.1039/b816714c

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Giuseppe Digilio, Valeria Catanzaro, Franco Fedeli, Eliana Gianolio, Valeria Menchise, Roberta Napolitano, Concetta Gringeri and Silvio Aime, Chem. Commun., 2009 , 893
DOI: 10.1039/b820593k

‘Two is better than one’—probes for dual-modality molecular imaging
Lucy E. Jennings and Nicholas J. Long, Chem. Commun., 2009 , 3511
DOI: 10.1039/b821903f

Retracted article: Shell-cross-linked stable multifunctional polymeric vesicles as magnetic resonance imaging contrast agents and drug nanocarriers
Xiaoqiang Yang, Jamison J. Grailer, Srikanth Pilla, Douglas A. Steeber, Shaoqin Gong, Yinghua Chen and Guihua Chen, Mol. BioSyst., 2009
DOI: 10.1039/b903719e

Integration column: Biofunctional polymeric nanoparticles for spatio-temporal control of drug delivery and biomedical applications
Dominique A. Rothenfluh and Jeffrey A. Hubbell, Integr. Biol., 2009 , 1 , 446
DOI: 10.1039/b907627c

Global signatures of protein and mRNA expression levels
Raquel de Sousa Abreu, Luiz O. Penalva, Edward M. Marcotte and Christine Vogel, Mol. BioSyst., 2009 , 5 , 1512
DOI: 10.1039/b908315d

Investigation of microsphere-mediated cellular delivery by chemical, microscopic and gene expression analysis
Lois M. Alexander, Salvatore Pernagallo, Alessandra Livigni, Rosario M. Sánchez-Martín, Joshua M. Brickman and Mark Bradley, Mol. BioSyst., 2010 , 6 , 399
DOI: 10.1039/b914428e

Simultaneous multiple element detection by particle beam/hollow cathode-optical emission spectroscopy as a tool for metallomic studies: Determinations of metal binding with apo-transferrin
C. Derrick Quarles, Jr., Julia L. Brumaghim and R. Kenneth Marcus, Metallomics, 2010 , 2 , 154
DOI: 10.1039/b916073f

Nanotechnology for in vitro neuroscience
Daniel R. Cooper and Jay L. Nadeau, Nanoscale, 2009 , 1 , 183
DOI: 10.1039/b9nr00132h

Quantum dot-based theranostics
Yi-Ping Ho and Kam W. Leong, Nanoscale, 2010 , 2 , 60
DOI: 10.1039/b9nr00178f