Strand invasion

Definition: The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.

ID: GO:0042148

Synonyms:

Articles referencing this term

Effect of terminal amino acids on the stability and specificity of PNA–DNA hybridisation
Nicole C. Silvester, G. R. Bushell, Debra J. Searles and Christopher L. Brown, Org. Biomol. Chem., 2007 , 5 , 917
DOI: 10.1039/b615567g

Bioinspired functional block copolymers
Hans G. Börner and Helmut Schlaad, Soft Matter, 2007 , 3 , 394
DOI: 10.1039/b615985k

Moving marks: Dynamic histone modifications in yeast
Jocelyn E. Krebs, Mol. BioSyst., 2007 , 3 , 590
DOI: 10.1039/b703923a

Single molecule studies of homologous recombination
Ilya J. Finkelstein and Eric C. Greene, Mol. BioSyst., 2008 , 4 , 1094
DOI: 10.1039/b811681b

Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(ii) macrocycle
Ta-Sheng Andrew Tseng and Judith N. Burstyn, Chem. Commun., 2008 , 6209
DOI: 10.1039/b812183d

Strand invasion of conventional PNA to arbitrary sequence in DNA assisted by single-stranded DNA binding protein
Takumi Ishizuka, Kosuke Otani, Jun Sumaoka and Makoto Komiyama, Chem. Commun., 2009 , 1225
DOI: 10.1039/b813975j

Alternate dab-aegPNAs: synthesis, nucleic acid binding studies and biological activity
Giovanni N. Roviello, Domenica Musumeci, Andrea De Cristofaro, Domenica Capasso, Sonia Di Gaetano, Enrico M. Bucci and Carlo Pedone, Mol. BioSyst., 2010 , 6 , 199
DOI: 10.1039/b910278g