Friedel-Crafts acylation

Definition: A carbon-carbon coupling reaction between an arene and a carbonyl compound (usually an acyl halide) to give an aryl ketone. The reaction is catalysed by a Lewis acid.

ID: RXNO:0000045


More about the RSC Name Reaction Ontology (RXNO)

Articles referencing this term

Anti-Markovnikov hydroarylation of styrenes catalyzed by an in situ generated ruthenium complex
Rémi Martinez, Jean-Pierre Genet and Sylvain Darses, Chem. Commun., 2008 , 3855
DOI: 10.1039/b806121a

Cymantrene conjugation modulates the intracellular distribution and induces high cytotoxicity of a cell-penetrating peptide
Ines Neundorf, Jan Hoyer, Katrin Splith, Robert Rennert, Harmel W. Peindy N’Dongo and Ulrich Schatzschneider, Chem. Commun., 2008 , 5604
DOI: 10.1039/b812799a

Controlled ring-opening polymerisation of cyclic esters: polymer blocks in self-assembled nanostructures
Andrew P. Dove, Chem. Commun., 2008 , 6446
DOI: 10.1039/b813059k

A thermal 6π electrocyclization strategy towards taiwaniaquinoids. First enantiospecific synthesis of (−)-taiwaniaquinone G
Enrique Alvarez-Manzaneda, Rachid Chahboun, Eduardo Cabrera, Esteban Alvarez, Ali Haidour, Jose Miguel Ramos, Ramón Alvarez-Manzaneda, Mohammed Hmamouchi and Hakima Es-Samti, Chem. Commun., 2009 , 592
DOI: 10.1039/b816812a

Preparation of a novel poly(vinylsulfonic acid)-grafted solid phase acid catalyst and its use in esterification reactions
Teruyuki Okayasu, Kei Saito, Hiroyuki Nishide and Milton T. W. Hearn, Chem. Commun., 2009 , 4708
DOI: 10.1039/b823177j

Vapor-phase silylation for the construction of monomeric silica puncheons in the interlayer micropores of Al-MWW layered precursor
Satoshi Inagaki and Takashi Tatsumi, Chem. Commun., 2009 , 2583
DOI: 10.1039/b823524d

Novel highly proton conductive sulfonated poly(p-phenylene) from 2,5-dichloro-4-(phenoxypropyl)benzophenone as proton exchange membranes for fuel cell applications
Surasak Seesukphronrarak and Akihiro Ohira, Chem. Commun., 2009 , 4744
DOI: 10.1039/b908140b

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DOI: 10.1039/c002558e

Facile synthesis and strong antiproliferative activity of disubstituted diphenylmethylidenyl-[3]ferrocenophanes on breast and prostate cancer cell lines
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DOI: 10.1039/c0md00026d

Synthesis and biological evaluation of N-(4-phenylthiazol-2-yl)cinnamamide derivatives as novel potential anti-tumor agents
Yong Luo, Yongxia Zhu, Kai Ran, Zhihao Liu, Ningyu Wang, Qiang Feng, Jun Zeng, Lidan Zhang, Bing He, Tinghong Ye, Shirui Zhu, Xiaolong Qiu and Luoting Yu, Med. Chem. Commun., 2015 , 6 , 1036
DOI: 10.1039/c4md00573b