Baylis-Hillman reaction

Definition: A carbon-carbon coupling of an aldehyde to an activated alkene in the presence of a nucleophilic base to give an alpha-hydroxyalkylated compound.

ID: RXNO:0000076


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Articles referencing this term

Asymmetric catalytic aza-Morita–Baylis–Hillman reaction (aza-MBH): an interesting functional group-caused reversal of asymmetric induction
Min Shi, Ming-Juan Qi and Xu-Guang Liu, Chem. Commun., 2008 , 6025
DOI: 10.1039/b814500h

Direct enantioselective aldol reactions catalyzed by a proline–thiourea host–guest complex
Ömer Reis, Serkan Eymur, Barbaros Reis and Ayhan S. Demir, Chem. Commun., 2009 , 1088
DOI: 10.1039/b817474a

Mass spectrometric screening of chiral catalysts and catalyst mixtures
Constanze Annelie Müller, Christian Markert, Antje Maria Teichert and Andreas Pfaltz, Chem. Commun., 2009 , 1607
DOI: 10.1039/b822382c

Chemo-/regioselective synthesis of 6-unsubstituted dihydropyrimidinones, 1,3-thiazines and chromones via novel variants of Biginelli reaction
Jie-Ping Wan and Yuan-Jiang Pan, Chem. Commun., 2009 , 2768
DOI: 10.1039/b901112a

Oxidative coupling of amines and ketones by combined vanadium- and organocatalysis
Abhishek Sud, Devarajulu Sureshkumar and Martin Klussmann, Chem. Commun., 2009 , 3169
DOI: 10.1039/b901282f

Recent extensions of the Morita–Baylis–Hillman reaction
Guang-Ning Ma, Jia-Jun Jiang, Min Shi and Yin Wei, Chem. Commun., 2009 , 5496
DOI: 10.1039/b909405a