Biginelli reaction

Definition: A three-component coupling of a beta-keto ester, an aldehyde and urea to give a 3,4-dihydropyrimidinone.

ID: RXNO:0000236


More about the RSC Name Reaction Ontology (RXNO)

Articles referencing this term

From one to three: a serine derivate manipulated homochiral metal-organic framework
Miao Wang, Ming-Hua Xie, Chuan-De Wu and Yan-Guang Wang, Chem. Commun., 2009 , 2396
DOI: 10.1039/b823323c

Chemo-/regioselective synthesis of 6-unsubstituted dihydropyrimidinones, 1,3-thiazines and chromones via novel variants of Biginelli reaction
Jie-Ping Wan and Yuan-Jiang Pan, Chem. Commun., 2009 , 2768
DOI: 10.1039/b901112a