Alkyne-azide click reaction

Definition: A [3+2] cycloaddition reaction between an azide and an alkyne to give a 1,2,3-triazole, needing only heat to proceed.

ID: RXNO:0000269


More about the RSC Name Reaction Ontology (RXNO)

Articles referencing this term

Click chemistry as a route to surface functionalization of polymer particles dispersed in aqueous media
Craig Edward Evans and Peter Alfred Lovell, Chem. Commun., 2009 , 2305
DOI: 10.1039/b821758k

Modular synthesis of biologically active phosphatidic acid probes using click chemistry
Matthew D. Smith, Christopher G. Sudhahar, Denghuang Gong, Robert V. Stahelin and Michael D. Best, Mol. BioSyst., 2009 , 5 , 962
DOI: 10.1039/b901420a

Prenyltransferase substrate binding pocket flexibility and its application in isoprenoid profiling
Youli Xiao, Miranda Machacek, Kent Lee, Tomohisha Kuzuyama and Pinghua Liu, Mol. BioSyst., 2009 , 5 , 913
DOI: 10.1039/b902370d

Immunotherapy for cancer: synthetic carbohydrate-based vaccines
Therese Buskas, Pamela Thompson and Geert-Jan Boons, Chem. Commun., 2009 , 5335
DOI: 10.1039/b908664c

Magnetic peptide nucleic acids for DNA targeting
Giuseppe Prencipe, Stefano Maiorana, Paolo Verderio, Miriam Colombo, Paola Fermo, Enrico Caneva, Davide Prosperi and Emanuela Licandro, Chem. Commun., 2009 , 6017
DOI: 10.1039/b911449a

1,2,3-Triazole-boranes: stable and efficient reagents for ketone and aldehyde reductive amination in organic solvents or in water
Wenyan Liao, Yunfeng Chen, Yuxiu Liu, Haifeng Duan, Jeffrey L. Petersen and Xiaodong Shi, Chem. Commun., 2009 , 6436
DOI: 10.1039/b915361f

Thiol-ene “click” reactions and recent applications in polymer and materials synthesis
Andrew B. Lowe, Polym. Chem., 2010 , 1 , 17
DOI: 10.1039/b9py00216b

Sequential double click reactions: a highly efficient post-functionalization method for optoelectronic polymers
Yongrong Li and Tsuyoshi Michinobu, Polym. Chem., 2010 , 1 , 72
DOI: 10.1039/b9py00238c

Aminonaphthalimide-based imidazolium podands for turn-on fluorescence sensing of nucleoside polyphosphates
Dehui Wang, Xiaolin Zhang, Cheng He and Chunying Duan, Org. Biomol. Chem., 2010 , 8 , 2923
DOI: 10.1039/c004148c