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Communication

Chem. Commun., 2008, 169 - 171, DOI: 10.1039/b715602b

Chain-like assembly of gold nanoparticles on artificial DNA templates via click chemistry

Monika Fischler, Alla Sologubenko, Joachim Mayer, Guido Clever, Glenn Burley, Johannes Gierlich, Thomas Carell and Ulrich Simon

We present a new type of azide-functionalized gold nanoparticle and their coupling to an alkyne-modified DNA duplex using the copper(I)-catalyzed Huisgen cycloaddition (click chemistry), resulting in a chain-like assembly of nanoparticles on the DNA template.

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