MRC Laboratory of Molecular Biology, Cambridge, UK
M. Madan Babu is a Programme Leader at the MRC Laboratory of Molecular Biology, Cambridge, UK. His research group aims to gain a detailed understanding of how regulation is achieved at distinct levels of organization in cellular systems with the ultimate objective of deriving general principles of living systems at a molecular level. To this end, his group develops approaches to analyze, integrate, mine and extract knowledge from multiple large-scale omics datasets to uncover complex patterns, thereby making new discoveries.
Specifically, his group investigates regulation at three levels of organization: molecules, processes and genomes. At the molecular level, they aim to discover novel features of regulatory and signalling proteins such as G protein-coupled receptors. At the process level, they aim to understand how the different regulatory mechanisms contribute to cellular homeostasis. At the genome level, they study the interplay between regulation and genome evolution.
Madan's work has been recognized with national and international awards including the most recent Blavatnik Awards Life Sciences Laureate (2018), ISCB Innovator Award (2018), Francis Crick Medal and Lecture from the Royal Society (2015), Protein Society Young Investigator Award (2014), Lister Prize (2014), Biochemical Society of UK’s Colworth Medal (2013), Royal Society of Chemistry’s Molecular BioSystems Award (2011), British Genetics Society’s Balfour Award (2011), and the EMBO Young Investigator Award (2010). Madan is an elected member of EMBO (2016) and a Fellow of the Royal Society of Chemistry (2017).