Chemistry World Entrepreneur of the Year Award 2016 Winner

Simon Hirst
Simon Hirst


Simon Hirst received this award for entrepreneurship in UK Life Sciences industry and for founding Sygnature Discovery. The company provides advanced scientific research into medicinal drug discovery programmes for pharmaceutical and biotechnology companies worldwide. Growth has been rapid and sustainable and Sygnature now employs over 160 staff and continues to expand its expertise. To date Sygnature scientists are named inventors on over 50 patents.


Sygnature was founded by Dr Hirst in 2004. Simon is a medicinal chemist by training with 26 years of experience in the pharmaceutical industry. Simon is the driving force behind the commercial success of the business, the strategic direction of the organisation and the architect of Sygnature's growing reputation within the pharmaceutical industry. Over the past 12 years, the size and scope of projects placed with Sygnature have grown in size and complexity and therefore value. This is a testament to the ability of the team of over 130 scientists that Simon has created to undertake top class research and development work. 

About the company

Sygnature is the UK's largest independent provider of integrated drug discovery expertise. Capabilities include, medicinal chemistry, in vitro bioscience, computational chemistry, DMPK and protein crystallography. The mission is to accelerate new medicines into development to treat patients with debilitating diseases such as cancer, respiratory disease and Alzheimer's.

Related Links

Link icon Dr Hirst's website
Sygnature Discovery

External links will open in a new browser window