2023 Chemistry Biology Interface open Prize: Khorana Prize Winner
Professor Tom Brown, University of Oxford
Awarded for major contributions in the nucleic acid field, including the synthesis of biocompatible artificial DNA, and molecular tools for genetic analysis and diagnostics.
Professor Brown’s research involves the use of chemical synthesis to make analogues of nucleic acids that can be used in biological and biomedical applications. These include genetic analysis and diagnostics to identify mutations that can lead to disease, and forensic analysis and therapeutic applications. His research group are developing methods to get small nucleic acid strands efficiently into cells where they can interact with the genetic machinery. This will have implications for the treatment of diseases that are resistant to current therapies.
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