Applied Interpretation of LC-MS Mass Spectra

This classroom-based course provides an introduction to mass spectral interpretation, covering all the fundamental tools and rules when examining high quality full-scan LC-MS data.

Delegates will benefit from a greater understanding of how to interpret the mass spectra produced by Electrospray Ionisation (ESI) and Atmospheric Pressure Chemical Ionisation (APCI).

From learning to quickly recognise from the spectrum if the analyte is aliphatic or aromatic in nature; to learning to interpret the number of carbon atoms, heteroatoms and degree of unsaturation; and understand isotopes, isomers, logical losses, cleavages and rearrangements to produce a mass spectral fingerprint of the compound.

The course uses a combination of classroom-based presentations to introduce the theory with a high proportion of tutor-supported tutorial exercises on LC-MS spectral data to facilitate and reinforce the learning process.

If you wish to learn the fundamentals of LC-MS mass spectral interpretation for the identification of unknowns or to enhance your understanding of fragmentation patterns, to assist in accurate identification when using library search programs, then this course is for you.

Prerequisites

This course is recommended for those who have a good background in organic chemistry and at least six months experience as a LC-MS operator, and is interested in structural elucidation of compounds amenable to analysis by LC-MS.

Additional information

Includes: lunch and refreshments; hardcopy of the training manual in colour, practical exercises and answers; certificate of attendance; ability to discuss own problems.

Can also be delivered as a onsite/in-house, offsite or online course.