Fundamentals of GC-MS

Course overview

A course designed to highlight the powerful possibilities of GC analysis with spectral detection. Tuning and tune reports will be explained, and instruction given in the use of tune reports as a powerful diagnostic tool. The functionality of the MS will be discussed in detail including principles of the quadrupole mass filter. Ion detection devices will be detailed, and the use of electron and chemical ionization sources will be investigated with applicability to practical situations. General interpretation strategies will also be considered to provide a well rounded fundamental knowledge.

Session 1 | Runtime - 90 min

• Introduction to GC-MS
• What Can GC-MS Do for Us?
• Carrier Gas Purity and Flow Control
• Sample Introduction
• Column Selection and Interfacing

Session 2 | Runtime - 112 min

• Ion Source Anatomy
• Electron Ionization
• Gas Phase Chemistry
• Autotuning
• Source Parameter Optimisation
• Chemical Ionisation
• Ion Source Problems
• Obtaining Representative Spectra
• Library Searching
• Basic Interpretation

Session 3 | Runtime - 65 min

• Mass Analysers Introduction
• Mass Analyser Definitions
• Quadrupoles
• Ion Traps
• ToF
• FT-MS Orbitraps

Session 4 | Runtime - 85 min

• Introduction to GC-MS/MS Data Interpretation
• GC-MS/MS – Why?
• Nature of GC-MS Data
• Interpretation

Each video session is accompanied by supporting modules from CHROMacademy and we will use the animations within CHROMacademy to clearly illustrate the science and processes that are being discussed. All four sessions should be completed in order to gain the full training. The final assessment must be completed in order to gain your certificate of completion.

Course Delivery & Duration

• 4 video sessions each session is between 1-2 hours long
• Tutor supported with access to our chromatography experts
• Supporting training material
• Course assessment with certificate

Our CHROMacademy tutors will deliver four video training sessions which you can access on demand. They will provide online support and tutoring where necessary.

Prerequisites

This course has been designed for anyone who is new to GC-MS or those wishing to understand more about the practicalities of GC-MS analysis.

Additional information

Sign up for 1-year CHROMacademy Premier Membership ($469.00 / £349.00 / €419.00 per year) and you get access to this course and FIVE other video courses - as well as hundreds of multi-media online modules in analytical science.