PhD MA CChem MRSC
I have 30 years’ experience of drug metabolism, pharmacokinetics, pharmacodynamics and bioanalysis in both discovery and development in the pharmaceutical industry (in Europe and USA), including both NCEs and biologics. I am well placed to offer expert analysis and advice in DMPK, and help clients find solutions to their problems in a wide variety of situations.
I use a variety of software to solve problems in modelling and simulation for PK and PK/PD profiles, and for prediction of human PK from in vitro and physical chemistry data.
In the real world of discovery support and pre-clinical development, many things happen which fall outside text-book descriptions. With a substantial knowledge of chemistry, physiology, animal behaviour and analytical methodology, I can offer sensible explanations for unexpected observations and ways to investigate and solve the problems that arise.