Our ChemSci Pick of the Week demonstrates the scalable synthesis of metal-organic-frameworks (MOFs) using ultrasonic or acoustic frequencies – rather than solvent-based approaches.
The team of researchers from McGill University, Canada, showed that scale-up from milligrams to 25g was straightforward using the mechanochemical technique which does not require milling media.
They demonstrated the use of their liquid-assisted resonant acoustic mixing (LA-RAM) methodology for the synthesis of three- and two-dimensional MOFs based on Zn(II), Co(II) and Cu(II), including a mixed ligand system.
Importantly, the LA-RAM approach also allowed the synthesis of the ZIF-L framework that has never been previously obtained in a mechanochemical environment, as well as its Co(II) analogue.
Straightforward scale-up from milligrams to at least 25g was demonstrated using the metastable framework ZIF-L as the model.
This work could lead to an alternative to less laborious and environmentally toxic solvent-based processes.