New modalities: Innovations in hit identification

Innovations in hit identification (Hit ID) are transforming drug discovery by integrating AI-driven virtual screening, giga-scale library screening, and advanced biophysical techniques to accelerate lead generation. These approaches are not only enabling faster identification of high-quality hits but also expanding the druggable interactome to include targets once considered intractable. The SCI “New modalities” series comprises focussed events addressing cutting-edge topics, and this year’s online symposium brings together world-class scientists at the forefront of hit identification for drug discovery.