Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru, India
Jayanta Haldar completed his undergraduate training at the Presidency College, University of Calcutta and he received his Master of Science and PhD from the Indian Institute of Science, Bangalore in 2005. He then pursued his Postdoctoral Research at the Department of Chemistry, Massachusetts Institute of Technology, USA till 2009. He then joined New Chemistry Unit at JNCASR as Assistant Professor (Faculty Fellow) in 2009 and currently he is an Associate Professor. He is also associated with the School of Advanced Materials (SAMat) at JNCASR. He has received several awards and honours such as the Ramanujan Fellowship Govt. of India, CDRI Excellence in Drug Research Award in Chemistry, Chemical Research Society of India (CRSI) Bronze Medal, Sheik Saqr Career Award Fellowship, etc.
Over the past decade, his lab has been persistently undertaking a diverse set of projects in the field of Medicinal Chemistry and Chemical Biology, with the aim of tackling and preventing antimicrobial resistance and infections. His group has established various chemical strategies and invented several antimicrobial solutions through rationally designed semi-synthetic antibiotics and new synthetic drug-candidates with novel mechanisms of action. Haldar group has adopted innovative approaches to target drug-resistant bacteria through development of new class of glycopeptide-antibiotics and metallo-β-lactamase inhibitors. Recently, his group has also developed antimicrobial peptide (AMP) mimics which can cure complex biofilm-related infections and engineered small-molecular antibiotic adjuvants which can, in combination, resensitize multiple classes of obsolete antibiotics ubiquitously, for tackling the most critical drug-resistant Gram-negative superbugs. As a part of the preventive strategy, Dr. Haldar’s group has engineered antimicrobial paints that prevent catheters/implant-associated infection and surgical-sealants that prevent/cure eye infections and promote wound-healing. Group has also developed antimicrobial coatings on Personal Protective Equipment (PPE) which can prevent the spread of bacterial, fungal and respiratory viral infections.