Joseph Chatt Award 2012 Winner
For his major contributions to the development and application of ENDOR spectroscopy for elucidating mechanisms of catalysis by metalloenzymes.
About the Winner
Brian Hoffman is Professor of Chemistry at Northwestern University. His research interests include electron paramagnetic resonance and electron-nuclear double resonance (ENDOR) of metalloenzymes; long-range electron transfer within protein complexes; and new porphyrazine metallomacrocycles. These days, a major focus of his ENDOR studies is enzymes with diatomic substrates, O2 for oxidations (eg. cytochromes P450, Nitric Oxide Synthase), and most especially reduction of N2 to NH3 (nitrogenase). He has authored more than 500 technical publications.
Brian obtained his B.S. degree in chemistry from the University of Chicago in 1962 and his Ph.D. from California Institute of Technology in 1966. In 1966-67 he held a NAS-NRC postdoctoral fellowship at Massachusetts Institute of Technology. He joined Northwestern as an Assistant Professor in 1967, was Associate Professor from 1971 to 1974 and was promoted to full professor in 1974.
Professor Hoffman's honors and awards include: Alfred P. Sloan Fellow (1971-73); National Institutes of Health Career Development Award (1972-77); Fellow, American Association for the Advancement of Science; Dow Research Professor of Chemistry (1990-1992); Bruker Prize for ESR, Royal Society of Chemistry (1997); Gold Medal International EPR Society (IES) (1999); Fellow of the American Academy of Arts & Sciences (2002); Member of the National Academy of Sciences (2006); Zavoisky Prize from the Russian Academy of Sciences (2007); Charles E. and Emma H. Morrison Professor of Chemistry (2007); Frontiers in Biological Chemistry Award, Max Planck Society (2008); Fellow of the International Society of Magnetic Resonance (ISMAR) (2009); Alfred Bader Award in Bioinorganic or Bioorganic Chemistry (2012).
Professor Hoffman's Webpage
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