Issue 10, 1997

Enantioselective synthesis of homoallylic alcohols using (E)-but-2-enyl-trichlorosilane and chiral diamines

Abstract

Condensation of aromatic aldehydes and (E)-but-2-enyl- trichlorosilane in the presence of (S)-(+)-4-(2-methylpropyl)-2-(2-pyridinyl)-2-oxazoline gives the corresponding homoallylic alcohols in excellent anti-diastereoselectivity (>99%) and good enantioselectivity (36–74%).

Article information

Article type
Paper

Chem. Commun., 1997, 919-920

Enantioselective synthesis of homoallylic alcohols using (E)-but-2-enyl-trichlorosilane and chiral diamines

R. M. Angell, A. G. M. Barrett, D. Christopher Braddock, S. Swallow and B. D. Vickery, Chem. Commun., 1997, 919 DOI: 10.1039/A701244F

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