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Communication

Chem. Commun., 2008, 3771 - 3773, DOI: 10.1039/b807039c


Polymerase chain reaction-based biochemical logic gate coupled with cell-free transcription–translation of green fluorescent protein as a report gate

Takahiko Nojima, Takatoki Yamamoto, Hiroshi Kimura and Teruo Fujii


Polymerase chain reaction-based biochemical logic gates were designed for AND, OR, NOT, and AND–NOT operations, whose output signal is reported by coupled cell-free transcription–translation of green fluorescent protein.

Graphical abstract image for this article  (ID: b807039c)