Reactivity of an antimetastatic organometallicruthenium compound with metallothionein-2: relevance to the mechanism of action†
Abstract
The reaction of metallothionein-2 (MT-2) with the organometallic antitumour compound
* Corresponding authors
a
Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland
E-mail:
paul.dyson@epfl.ch, angela.casini@epfl.ch
Fax: (+41) 21 6939865
Tel: (P. D.) +41 21 6939854
b Department of Biochemistry, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland
c Department of Chemistry, University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino, Italy
The reaction of metallothionein-2 (MT-2) with the organometallic antitumour compound
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