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Letter
New J. Chem., 2007, 31, 193 - 195, DOI: 10.1039/b616085a
Bis-8-hydroxyquinoline ligands as potential anti-Alzheimer agents
Céline Deraeve, Marguerite Pitié, Honoré Mazarguil and Bernard Meunier
A strategy based on the use of a tetradentate ligand containing two linked 8-hydroxyquinolines allowed a significant increase in the ability to protect against
-amyloid peptide precipitation in the presence of Cu(II), Zn(II) and Fe(III) when compared to clioquinol, a 8-hydroxyquinoline derivative active in vivo.
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